A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT03307330
Status
Recruiting
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Conditions

  • Obstructive Sleep Apnea of Adult

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Study Details

Studies show that sleep apnea increases the risk of cardiovascular disease and is associated with obesity. However, it is unclear how sleep apnea affects fat tissue. Studies have shown that fat tissue is likely involved in developing cardiovascular disease. The purpose of this study is to see how sleep apnea changes fat tissue.

Key Dates

Start date
Jan 8, 2018
Status verified
Feb 2026
Primary completion
Dec 31, 2029
Completion
Dec 31, 2029

Study Design

Enrollment
120 participants (estimated)

Arms

  • Arm: Obstructive Sleep Apnea
    Obstructive sleep apnea is defined as having Apnea hypopnea index (AHI) \>=5
  • Arm: Non-Obstructive Sleep Apnea
    Non-Obstructive sleep apnea is defined as having Apnea hypopnea index (AHI) \< 5

Primary Outcome Measure

Prevalence of dual positive p16^IND4A and gamma H2AX cells in adipose tissue [ Time Frame: Day 2 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo ClinicRochesterMinnesota55901
Somers_CPL LAB
[email protected]
507-255-8794
Virend Somers, MD, Ph.D
[email protected]
507-255-1144

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By research site
Mayo Clinic· Rochester, MN

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