Paid Clinical Trials in Philadelphia, PA

As of June 2026, 2,086 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,086 clinical trials

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Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

for Migraine

35 locations incl. Flagstaff

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70

Code: NCT06972056·Phase 4·Recruiting

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A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

for Developmental and Epileptic Encephalopathy 1

6 locations incl. La Jolla

Sponsor: Praxis Precision Medicines

Sex: All·Age: 2 - 65

Code: NCT07010471·Phase 3·Recruiting

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Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

for Urothelial Carcinoma

2 locations incl. Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07043972·Phase 2·Recruiting

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An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-sensitive Prostate Cancer

Drug: JSB462

21 locations incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT06991556·Phase 2·Recruiting

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Intravesical Treatment of Bladder Cancer at Home, Multi-modal Treatment Support

for Bladder Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07048496·Recruiting

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Radiation Free Study

for Aortic Aneurysm

4 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT06549348·Recruiting

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Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

for Diabetic Foot Ulcer

8 locations incl. Santa Rosa

Sponsor: Cellution Biologics

Sex: All·Age: 18+

Code: NCT07014176·Phase 4·Recruiting

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TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

39 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting

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Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)

for Geriatric Assessment

3 locations incl. Princeton

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 70+

Code: NCT06870617·Recruiting

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Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

for Preterm Delivery

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 14+·Accepts healthy volunteers

Code: NCT06980025·Phase 3·Recruiting

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OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition

for Malignant Pleural Mesothelioma

1 location in Philadelphia

Sponsor: Oncotelic Inc.

Sex: All·Age: 18+

Code: NCT05425576·Phase 2·Not Yet Recruiting

FIT-ATOMIC Exercise Feasibility Trial

for Neuroinflammatory Diseases

2 locations incl. La Jolla

Sponsor: The Hospital for Sick Children

Sex: All·Age: 11 - 25

Code: NCT06870968·Not Yet Recruiting

Non-invasive and Continuous Blood Pressure Monitoring

for Blood Pressure

1 location in Philadelphia

Sponsor: Vena Vitals

Sex: All·Age: 18+

Code: NCT06887465·Not Yet Recruiting

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

for Amyotrophic Lateral Sclerosis (ALS)

15 locations incl. Phoenix

Sponsor: Brainstorm-Cell Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06973629·Phase 3·Not Yet Recruiting

Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity

for Primary Sjögren's Syndrome

Drug: IMVT-1402

29 locations incl. Covina

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 74

Code: NCT06979531·Phase 2·Recruiting

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Dental Implant Healing With TNF-Alpha Inhibitors

for Edentulism

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06538870·Recruiting

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Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

for Atrial Fibrillation (AF)

12 locations incl. Jonesboro

Sponsor: Vektor Medical

Sex: All·Age: 22+

Code: NCT06935591·Recruiting

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

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Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

for Sickle Cell Disease (SCD)

2 locations incl. Atlanta

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 50

Code: NCT06665997·Phase 4·Recruiting

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Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

for Preterm Birth

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 16 - 55

Code: NCT06826859·Phase 1, Phase 2·Recruiting

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

37 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting

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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

35 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting

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Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

for Allergy

56 locations incl. Birmingham

Sponsor: DBV Technologies

Sex: All·Age: 1 - 3

Code: NCT07003919·Phase 3·Recruiting

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A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

13 locations incl. Los Angeles

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting

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Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

for Nausea

12 locations incl. Scottsdale

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18+

Code: NCT06464926·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

59 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06959225·Phase 3·Recruiting

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

55 locations incl. Sheffield

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06961214·Phase 3·Recruiting

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A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: Pegcetacoplan

68 locations incl. Gilbert

Sponsor: Apellis Pharmaceuticals, Inc.

Sex: All·Age: 60+

Code: NCT07215390·Phase 2·Recruiting

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PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma

for Refractory Neuroblastoma

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 1+

Code: NCT07007117·Phase 1·Recruiting

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

24 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting

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Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

for Locally Advanced Pancreatic Adenocarcinoma

7 locations incl. Scottsdale

Sponsor: EXACT Therapeutics AS

Sex: All·Age: 18+

Code: NCT06850623·Phase 2·Recruiting

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ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

for Aortic Regurgitation

27 locations incl. Burlingame

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: All ages

Code: NCT06608823·Recruiting

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Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

for Childhood Astrocytoma

20 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 22

Code: NCT06894979·Phase 1·Recruiting

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AERA Pediatrics Registry

for Dysfunction of Eustachian Tube

6 locations incl. Palo Alto

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: Up to 18

Code: NCT07071298·Recruiting

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An Observational Study of Individuals With Isolated Dystonia

for Isolated/Primary Dystonia That Affects More Than One Region of the Body

29 locations incl. Scottsdale

Sponsor: Vima Therapeutics

Sex: All·Age: 12 - 65

Code: NCT07111663·Recruiting

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Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

for Phantom Pain Following Amputation of Lower Limb

3 locations incl. Philadelphia

Sponsor: Albert Einstein Healthcare Network

Sex: All·Age: 18 - 100

Code: NCT07044323·Recruiting

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Neonatal Platelet Transfusion Threshold Trial

for Thrombocytopenia

20 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 1 Hour - 48 Hours·Accepts healthy volunteers

Code: NCT06676904·Recruiting

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Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

for Post-ligation Cardiac Syndrome

19 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 3 Months

Code: NCT06679855·Phase 3·Recruiting

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VIZ ACCESS HCM - Multi-Site Registry

for Hypertrophic Cardiomyopathy

3 locations incl. Atlanta

Sponsor: Viz.ai, Inc.

Sex: All·Age: 18+

Code: NCT07103057·Recruiting

Apply to this trial