Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Albert Einstein Healthcare Network
Study ID
NCT07044323
Status
Recruiting
Apply to this trial

Conditions

  • Amputation
  • Phantom Pain Following Amputation of Lower Limb

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Active Virtual Reality Treatment — BEHAVIORAL
    The self-administered active VR treatment will consist of 8 twice-weekly sessions, each approximately 1 hour in duration, during which subjects will participate in a variety of Virtual Reality active games that require leg movements while receiving high-quality visual feedback of the missing lower leg.

Study Details

After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).

Key Dates

Start date
Jun 16, 2025
Status verified
Aug 2025
Primary completion
May 31, 2026
Completion
May 31, 2026

Study Design

Enrollment
44 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Home-based treatment
    Self-administered Active Virtual Reality treatment

Primary Outcome Measure

Changes in pain intensity [ Time Frame: pre each intervention (8 sessions); immediately after each intervention (8 session); baseline, pre-intervention; immediately after the end of the intervention; 1 week after the end of the intervention; 8 weeks after the end of the intervention. ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Jefferson Moss Rehabilitation Research InstitutePhiladelphiaPennsylvania19027
Rand Williamson
[email protected]
215-663-6321
University of PennsylvaniaPhiladelphiaPennsylvania19122
Elisabetta Ambron
[email protected]
215-573-4336
University of WashingtonSeattleWashington98195
Jing-Sheng Li
[email protected]
215-663-6321

Find similar trials in Philadelphia, PA

By research site
Jefferson Moss Rehabilitation Research Institute· Philadelphia, PAUniversity of Pennsylvania· Philadelphia, PAUniversity of Washington· Seattle, WA

Related Studies