Clinical Trials at University of Pennsylvania

As of June 2026, 377 paid clinical trials are recruiting at University of Pennsylvania, located at Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, phone (215) 898-8001 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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377 clinical trials at University of Pennsylvania

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Nerve Transfer to Improve Function in High Level Tetraplegia

for Cervical Spinal Cord Injury

9 locations incl. Stanford

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06288763·Recruiting

Apply to this trial

A Global Study of the PETAL Consortium

for T-Cell and NK-Cell Neoplasm

10 locations incl. Duarte

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06067347·Recruiting

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Prostate Tissue BioBank

for Prostate Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Male·Age: 18+

Code: NCT06659614·Recruiting

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

18 locations incl. Los Angeles

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting

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A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for Neoplasms

11 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06150157·Phase 1·Recruiting

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Transforming Hemodialysis-Related Vascular Access Education

for Chronic Kidney Disease

3 locations incl. Baltimore

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05997875·Recruiting

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

for Esophageal Stricture

34 locations incl. Birmingham

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561114·Phase 3·Recruiting

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Evaluation of the GORE® Ascending Stent Graft

for Aortic Aneurysm, Thoracic

41 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05800743·Enrolling By Invitation

A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

for Hematologic Malignancy

17 locations incl. Duarte

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT06208878·Enrolling By Invitation

[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

for Breast Cancer

Drug: Ribociclib

6 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05870579·Phase 1·Recruiting

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TmCD19-IL18 in CD19+ Cancers

for Non Hodgkin Lymphoma

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05989204·Phase 1·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

for Cervical Cancer

3 locations incl. Voorhees Township

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05758688·Phase 2·Recruiting

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Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

for Becker Muscular Dystrophy

24 locations incl. Little Rock

Sponsor: Edgewise Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06066580·Phase 2·Enrolling By Invitation

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

33 locations incl. Scottsdale

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting

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Integrating Brain, Neurocognitive, and Computational Tools in OUD

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60

Code: NCT06136247·Recruiting

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Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

for Prodromal Parkinsons Disease

2 locations incl. New Haven

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+

Code: NCT07265596·Phase 2·Recruiting

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Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

for Ewing Sarcoma

Drug: Cabozantinib

4 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 - 40

Code: NCT06156410·Phase 1·Recruiting

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The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

for Aortoiliac Occlusive Disease

26 locations incl. Little Rock

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05811364·Recruiting

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A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

for Subacute Cutaneous Lupus Erythematosus

13 locations incl. Birmingham

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT06044337·Phase 3·Enrolling By Invitation

FES BPET-DBT in Newly Diagnosed Breast Cancer

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05659797·EARLY_Phase 1·Recruiting

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A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

for Obesity

3 locations incl. New York

Sponsor: University of Pittsburgh

Sex: All·Age: 25 - 59

Code: NCT05748158·Recruiting

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Left vs Left Randomized Clinical Trial

for Heart Failure

57 locations incl. Gilbert

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting

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Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for Surgery-Complications

20 locations incl. Little Rock

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05991453·Recruiting

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Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea

for Obstructive Sleep Apnea of Adult

9 locations incl. Aurora

Sponsor: Cryosa, Inc.

Sex: All·Age: 22 - 70

Code: NCT06008626·Recruiting

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Excision of Lymph Node Trial (EXCILYNT) (Mel69)

for Melanoma

7 locations incl. Atlanta

Sponsor: Craig L Slingluff, Jr

Sex: All·Age: 18+

Code: NCT05839912·Recruiting

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Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana

for Cervical Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05952141·Recruiting

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A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumors

11 locations incl. Los Angeles

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05836324·Phase 1·Recruiting

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Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15

for Tauopathies

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT06032026·EARLY_Phase 1·Recruiting

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CW2IP2: Imaging and Diagnostic Assessments

for Tauopathies

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT06083467·Recruiting

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting

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Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

for Familial Adenomatous Polyposis

17 locations incl. Scottsdale

Sponsor: Recursion Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05552755·Phase 1, Phase 2·Recruiting

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Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

for Sickle Cell Disease

9 locations incl. Birmingham

Sponsor: RTI International

Sex: All·Age: 18+

Code: NCT06385886·Recruiting

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Human Learning of New Structured Information Across Time and Sleep

for Learning

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05910762·Recruiting

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Phase IB/II of CPX-351 for Relapse Prevention in AML

for Acute Myeloid Leukemia (AML) in Remission

3 locations incl. Washington D.C.

Sponsor: Georgetown University

Sex: All·Age: 18+

Code: NCT04990102·Phase 1, Phase 2·Recruiting

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

26 locations incl. Tucson

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

59 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

11 locations incl. Los Angeles

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting

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A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

3 locations incl. North Little Rock

Sponsor: Brexogen Inc.

Sex: All·Age: 18+

Code: NCT06055361·Phase 1·Recruiting

Apply to this trial