Clinical Trials at Thomas Jefferson University

As of June 2026, 108 paid clinical trials are recruiting at Thomas Jefferson University, located at 111 S 11TH ST, SUITE 8270, PHILADELPHIA, PA 19107-4824, phone (215) 955-4038 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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108 clinical trials at Thomas Jefferson University

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

68 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting

Apply to this trial

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

for Diabetes

27 locations incl. Phoenix

Sponsor: Marinella Temprosa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05704309·Enrolling By Invitation

A Study of EP0031 in Patients With Advanced RET-altered Malignancies

for Advanced Solid Tumor

Drug: EP0031

18 locations incl. Los Angeles

Sponsor: Ellipses Pharma

Sex: All·Age: 18+

Code: NCT05443126·Phase 1, Phase 2·Recruiting

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Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

for Myelofibrosis

2 locations incl. Philadelphia

Sponsor: Karen Ballen, MD

Sex: All·Age: 18 - 75

Code: NCT05233618·Phase 1·Recruiting

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Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

for Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

18 locations incl. Birmingham

Sponsor: Electra Therapeutics Inc.

Sex: All·Age: 6+

Code: NCT05416307·Phase 2, Phase 3·Recruiting

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A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

for HER2-positive Advanced Solid Tumor

Drug: DB-1303/BNT323

35 locations incl. Cerritos

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05150691·Phase 1, Phase 2·Recruiting

Apply to this trial

Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery

for Disorder

4 locations incl. Portland

Sponsor: Unity Health Toronto

Sex: All·Age: 18 - 65

Code: NCT04754022·Recruiting

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

15 locations incl. Huntington Beach

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

for Peripheral Vascular Diseases

52 locations incl. Jonesboro

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT04674969·Recruiting

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Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

54 locations incl. Birmingham

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting

Apply to this trial

Adherus™ Dural Sealant in Spinal Procedures

for Spinal Duraplasty

14 locations incl. Duarte

Sponsor: Stryker Craniomaxillofacial

Sex: All·Age: 18 - 75

Code: NCT04498026·Enrolling By Invitation

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

25 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting

Apply to this trial

Stroke Thrombectomy and Aneurysm Registry

for Stroke

54 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting

Apply to this trial

Whole Exome Sequencing and Whole Genome Sequencing for Nonimmune Fetal/Neonatal Hydrops

for Nonimmune Fetal Hydrops

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 16 - 55

Code: NCT03911531·Recruiting

Apply to this trial

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for Functional Mitral Regurgitation

75 locations incl. Gilbert

Sponsor: Cardiac Dimensions, Inc.

Sex: All·Age: 18+

Code: NCT03142152·Recruiting

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Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

for Leukemia, Lymphocytic, Chronic, B-Cell

84 locations incl. Birmingham

Sponsor: Juno Therapeutics, a Subsidiary of Celgene

Sex: All·Age: 18+

Code: NCT03331198·Phase 1, Phase 2·Recruiting

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Systemic Hypothermia in Acute Cervical Spinal Cord Injury

for Spinal Cord Injury, Acute

7 locations incl. Phoenix

Sponsor: University of Miami

Sex: All·Age: 18 - 70

Code: NCT02991690·Recruiting

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

48 locations incl. Birmingham

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting

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Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis

for Multiple Sclerosis

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT03032601·Enrolling By Invitation

CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

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JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

for Non-Small Cell Lung Cancer

40 locations incl. La Jolla

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT02468024·Phase 3·Recruiting

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ALS/MND Natural History Study Data Repository

for ALS

14 locations incl. Loma Linda

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

44 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

16 locations incl. Birmingham

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting

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Maternal Newborn Health Registry

for Pregnancy Outcome Trends in Low-resource Geographic Areas

8 locations incl. Birmingham

Sponsor: NICHD Global Network for Women's and Children's Health

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01073475·Recruiting

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Spinal Cord Injury Registry - North American Clinical Trials Network

for Spinal Cord Injury

13 locations incl. Miami

Sponsor: Robert G. Grossman, MD

Sex: All·Age: 18+

Code: NCT00178724·Recruiting

Apply to this trial