Clinical Trials at Thomas Jefferson University

As of June 2026, 108 paid clinical trials are recruiting at Thomas Jefferson University, located at 111 S 11TH ST, SUITE 8270, PHILADELPHIA, PA 19107-4824, phone (215) 955-4038 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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108 clinical trials at Thomas Jefferson University

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

71 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting

Apply to this trial

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419777·Recruiting

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Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

for Gestational Diabetes

2 locations incl. Rochester

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06419803·Recruiting

Apply to this trial

Reducing Urban Cervical Cancer Disparities

for Cervical Cancer

3 locations incl. New Brunswick

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06416150·Recruiting

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Long-term Safety and Tolerability of BHV-7000

for Focal Epilepsy

115 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06443463·Phase 2·Enrolling By Invitation

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for Metastatic Colorectal Cancer

Drug: Bevacizumab

26 locations incl. Chandler

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT06252649·Phase 3·Recruiting

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

50 locations incl. Gilbert

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting

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Group Coaching Study for Life Goals

for Students

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07083713·Enrolling By Invitation

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

33 locations incl. Tucson

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting

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A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

for Glioblastoma

Drug: Niraparib

32 locations incl. Birmingham

Sponsor: Ivy Brain Tumor Center

Sex: All·Age: 18+

Code: NCT06388733·Phase 3·Recruiting

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IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for Advanced Melanoma

Drug: Nivolumab

37 locations incl. Tucson

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT06112314·Phase 3·Recruiting

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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

59 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06329401·Phase 2·Recruiting

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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

61 locations incl. Phoenix

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting

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SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. New Haven

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting

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The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

for Myasthenia Gravis

11 locations incl. Aurora

Sponsor: Ad scientiam

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05564936·Recruiting

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

for Multiple Myeloma

Drug: Talquetamab

49 locations incl. Clovis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06208150·Phase 3·Recruiting

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BLOCK-SAH - PPF-Block for Post-SAH Headache

for Subarachnoid Hemorrhage, Aneurysmal

11 locations incl. Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 85

Code: NCT06008795·Phase 2·Recruiting

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Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

for Chronic Subdural Hematoma

15 locations incl. Coral Gables

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT06181994·Recruiting

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

for Esophageal Stricture

34 locations incl. Birmingham

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561114·Phase 3·Recruiting

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A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

for Carcinoma, Non-small-Cell Lung

7 locations incl. Newnan

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06116786·Phase 1·Recruiting

Apply to this trial

The PEERLESS II Study

for Pulmonary Embolism

50 locations incl. Birmingham

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06055920·Recruiting

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LATe Cerclage in High-risk Pregnancies (LATCH)

for Premature Birth

2 locations incl. Charlotte

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06036446·Recruiting

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Assessing Patient Satisfaction and Confidence After Use of Educational Video to Augment Surgical Consent for Thyroid Surgery

for Thyroid Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06918223·Recruiting

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

33 locations incl. Scottsdale

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting

Apply to this trial

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

49 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting

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A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

for Type 1 Diabetes Mellitus With Hypoglycemia

38 locations incl. Birmingham

Sponsor: Zucara Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT05762107·Phase 2·Recruiting

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study

for Intra Cerebral Hemorrhage

26 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: All ages

Code: NCT05611918·Enrolling By Invitation

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

32 locations incl. Irvine

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting

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An Open-label Study of XEN1101 in Epilepsy

for Focal Epilepsy

53 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05718817·Phase 3·Enrolling By Invitation

Cannabis Use and Outcomes in Black and White Patients With Cancer

for Cancer

3 locations incl. Buffalo

Sponsor: State University of New York at Buffalo

Sex: All·Age: 21 - 99

Code: NCT06037681·Recruiting

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

11 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

30 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting

Apply to this trial

Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

10 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting

Apply to this trial

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

for H3 K27M

67 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05580562·Phase 3·Recruiting

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FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

Apply to this trial

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

Apply to this trial