Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,661 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,663 clinical trials

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A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for Huntington Disease

5 locations incl. Boston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 65

Code: NCT06826612·Phase 1, Phase 2·Recruiting

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Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi

for Melanoma

1 location in Pittsburgh

Sponsor: John Kirkwood

Sex: All·Age: 18+

Code: NCT06599619·Recruiting

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SNV4818 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

5 locations incl. Los Angeles

Sponsor: Pikavation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06736704·Phase 1, Phase 2·Recruiting

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Communication About Sexual Health in Gynecologic Cancer

for Gynecologic Cancers

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18+

Code: NCT06904339·Recruiting

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Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention

for Opioid Use Disorder

3 locations incl. Pittsburgh

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06843213·Recruiting

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A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

for Sickle Cell Disease

Drug: Etavopivat

50 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 12+

Code: NCT06612268·Phase 3·Recruiting

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Transitional Care Program for Fluid Overload in Cirrhosis

for Cirrhosis, Liver

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06174272·Recruiting

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for AIDS-Related Diffuse Large B-cell Lymphoma

6 locations incl. Duarte

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05077527·Phase 1·Recruiting

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Airway Data Collection With the Entarik Feeding Tube System

for Healthy

1 location in Philadelphia

Sponsor: Theranova, L.L.C.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06760572·Recruiting

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A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

for Chronic Migraine

Drug: Atogepant

31 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 12 - 17

Code: NCT06810505·Phase 3·Recruiting

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Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

for Bacterial Infection

10 locations incl. Torrance

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06709521·Phase 4·Recruiting

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A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors

for Advanced Solid Tumors

Drug: Bevacizumab

4 locations incl. Los Angeles

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06730750·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01

for Diabetic Retinopathy

8 locations incl. Beverly Hills

Sponsor: Vantage Biosciences Ltd

Sex: All·Age: 18+

Code: NCT06770933·Phase 2·Recruiting

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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

for Primary Open Angle Glaucoma

24 locations incl. Glendale

Sponsor: AbbVie

Sex: All·Age: 45+

Code: NCT06822738·Phase 3·Recruiting

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Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

for Aphasia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85

Code: NCT06842745·Phase 2·Recruiting

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A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

for Thrombocytopenia, Neonatal Alloimmune

Drug: Nipocalimab

12 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT06533098·Phase 3·Recruiting

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A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

for Neurofibromatosis Type 1

14 locations incl. Birmingham

Sponsor: Healx Limited

Sex: All·Age: 12+

Code: NCT06541847·Phase 2·Recruiting

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This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.

for Peripheral Nerve Injury Upper Limb

18 locations incl. Orlando

Sponsor: Neuraptive Therapeutics Inc.

Sex: All·Age: 18 - 80

Code: NCT06616025·Phase 3·Recruiting

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Non-Contact Low-Frequency Ultrasound Vs Standard LaLonde Protocol for Fingertip Injury Wound Healing

for Non-contact Low Frequency Ultrasound

1 location in Bethlehem

Sponsor: St. Luke's Hospital, Pennsylvania

Sex: All·Age: 18+

Code: NCT06813430·Recruiting

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A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: Remibrutinib

24 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06744920·Phase 3·Recruiting

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Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

for Cardiac Failure

7 locations incl. Aurora

Sponsor: Inova Health Care Services

Sex: All·Age: Up to 18

Code: NCT06532890·Recruiting

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Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer

for Ovary Cancer

2 locations incl. Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female·Age: 18+

Code: NCT06617923·Phase 2·Recruiting

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Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for Castration-Resistant Prostate Carcinoma

107 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632977·Phase 2·Recruiting

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REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

71 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting

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Robotic Rehabilitation of the Upper Limb in Subacute Stroke

for Stroke

1 location in Elkins Park

Sponsor: IRCCS San Raffaele Roma

Sex: All·Age: 18 - 85

Code: NCT06839482·Recruiting

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Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

for Oncologic Surgery

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 18 - 89

Code: NCT06731998·Recruiting

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

72 locations incl. Decatur

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting

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North American Comfilcon A Clinical Study

for Astigmatism

4 locations incl. Berkeley

Sponsor: CooperVision International Limited (CVIL)

Sex: All·Age: 8 - 75

Code: NCT06902584·Recruiting

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

19 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting

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A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

for Lung Cancer

14 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06618287·Phase 1, Phase 2·Recruiting

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A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for Pyoderma Gangrenosum

19 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06624670·Phase 3·Recruiting

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Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

for Chronic Lymphocytic Leukaemia

3 locations incl. Charlotte

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06651970·Phase 4·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for KRAS G12C Mutation

11 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06720987·Phase 1·Recruiting

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A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

for Anemia, Sickle Cell

4 locations incl. Wilmington

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 21

Code: NCT06290401·Recruiting

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Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

34 locations incl. Birmingham

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

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Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for Extensive-stage Small-cell Lung Cancer

32 locations incl. Tucson

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712355·Phase 3·Recruiting

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Non-Invasive Preeclampsia Screening and Biobank

for Preeclampsia (PE)

21 locations incl. Glendale

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06643741·Recruiting

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Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program

for Chronic Stress

5 locations incl. Harrisburg

Sponsor: Penn State University

Sex: All·Age: 11+·Accepts healthy volunteers

Code: NCT05789446·Recruiting

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Study of Olutasidenib and Temozolomide in HGG

for High Grade Glioma

11 locations incl. Aurora

Sponsor: Rigel Pharmaceuticals

Sex: All·Age: 12 - 39

Code: NCT06161974·Phase 2·Recruiting

Apply to this trial