Oncology Clinical Trials in Oklahoma City, OK

As of June 2026, 164 paid clinical trials are recruiting for Oncology in Oklahoma City, Oklahoma. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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164 clinical trials for Oncology

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

Apply to this trial

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

134 locations incl. Goodyear

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting

Apply to this trial

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

for Non-Small Cell Lung Cancer

Drug: Durvalumab

43 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05211895·Phase 3·Recruiting

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Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure

for Acute Myeloid Leukemia

Drug: Venetoclax

4 locations incl. Clovis

Sponsor: Brian Jonas

Sex: All·Age: 18+

Code: NCT04905810·Phase 2·Recruiting

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Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

for Breast Cancer, NOS

347 locations incl. Fairbanks

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 39

Code: NCT05108298·Recruiting

Apply to this trial

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

10 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

9 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+

Code: NCT04606914·Phase 2·Recruiting

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Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

for Anatomic Stage III Breast Cancer AJCC v8

4 locations incl. Gainesville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04550494·Phase 2·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

for Breast Cancer

19 locations incl. Tucson

Sponsor: Criterium, Inc.

Sex: All·Age: All ages

Code: NCT04567420·Phase 2·Recruiting

Apply to this trial

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for Advanced Cancer

40 locations incl. Birmingham

Sponsor: Artios Pharma Ltd

Sex: All·Age: 18+

Code: NCT04657068·Phase 1, Phase 2·Recruiting

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

331 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

32 locations incl. Irvine

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

Apply to this trial

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

for Cancer

41 locations incl. Tucson

Sponsor: Tizona Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT04485013·Phase 1·Recruiting

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A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

5 locations incl. Los Angeles

Sponsor: BioInvent International AB

Sex: All·Age: 18+

Code: NCT04219254·Phase 1, Phase 2·Recruiting

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1150 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

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A Study of Sigvotatug Vedotin in Advanced Solid Tumors

for Carcinoma, Non-Small Cell Lung

Drug: sigvotatug vedotin

105 locations incl. Anchorage

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04389632·Phase 1·Recruiting

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Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

for Prostate Adenocarcinoma

Drug: Apalutamide

345 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT04134260·Phase 3·Recruiting

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A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer

for NSCLC

18 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04077099·Phase 1, Phase 2·Recruiting

Apply to this trial

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

Apply to this trial

Clinical Pre-screening Protocol for Ovarian Cancer

for Ovarian Cancer

3 locations incl. Boston

Sponsor: Allarity Therapeutics

Sex: Female·Age: 18+

Code: NCT03877796·Recruiting

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

Apply to this trial

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

Apply to this trial

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

Apply to this trial

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

for Recurrent Ovarian Cancer

Drug: Cemiplimab

11 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT03564340·Phase 1, Phase 2·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

Apply to this trial

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

for Advanced/Metastatic Solid Tumors

23 locations incl. La Jolla

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT03526835·Phase 1, Phase 2·Recruiting

Apply to this trial

Combination of TATE and PD-1 Inhibitor in Liver Cancer

for Hepatocellular Carcinoma

3 locations incl. Orange

Sponsor: Teclison Ltd.

Sex: All·Age: 18 - 80

Code: NCT03259867·Phase 2·Recruiting

Apply to this trial

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

Apply to this trial

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

for Hematopoietic and Lymphatic System Neoplasm

140 locations incl. Birmingham

Sponsor: National Cancer Institute LAO

Sex: All·Age: 2 Months+

Code: NCT02474160·Recruiting

Apply to this trial

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting

Apply to this trial

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

for Breast Cancer

9 locations incl. Scottsdale

Sponsor: Proton Collaborative Group

Sex: Female·Age: 50+

Code: NCT01766297·Phase 2·Recruiting

Apply to this trial

Conditions in Oncology (Oklahoma City, OK)

Solid tumor· 36 Non-small cell lung cancer (NSCLC)· 23 Ovarian cancer· 16 Breast cancer· 15 Endometrial cancer· 15 Acute myeloid leukemia (AML)· 13 Cancer (any)· 12 Colorectal cancer· 11 Prostate cancer· 11 Hematologic malignancy· 9 Fallopian tube cancer· 8 Head and neck cancer· 8 Pancreatic cancer· 6 Melanoma· 6 Triple-negative breast cancer· 5 Liver cancer· 5 Metastatic breast cancer· 4 Gastric cancer· 4 Bladder cancer· 4 Kidney cancer· 4 Cervical cancer· 4 Leukemia (other)· 4 Non-Hodgkin lymphoma· 4 Diffuse large B-cell lymphoma (DLBCL)· 4 Myelodysplastic syndromes (MDS)· 3 HER2-positive breast cancer· 2 HER2-negative breast cancer· 2 Lung cancer· 2 Small cell lung cancer· 2 Esophageal cancer· 2 Gastroesophageal junction cancer· 2 Uterine cancer· 2 Multiple myeloma· 2 Chronic lymphocytic leukemia (CLL)· 2 Acute lymphoblastic leukemia· 2 Hodgkin lymphoma· 2 Skin cancer· 2 Osteosarcoma· 2 Neuroblastoma· 2 Metastatic colorectal cancer· 1 Colon cancer· 1 Gastrointestinal cancer· 1 Metastatic prostate cancer· 1 Glioma· 1 Brain metastases· 1 Myeloproliferative neoplasm· 1 Mantle cell lymphoma· 1 Small lymphocytic lymphoma· 1 Burkitt lymphoma· 1 Sarcoma· 1 Mesothelioma· 1