Paid Clinical Trials in Ohio

Ohio has 3,476 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,476 clinical trials

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A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer

for Small Cell Lung Cancer

6 locations incl. Orange

Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Sex: All·Age: 18 - 75

Code: NCT06592638·Phase 1·Recruiting

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A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors Cancer

11 locations incl. Los Angeles

Sponsor: Nimbus Wadjet, Inc.

Sex: All·Age: 18 - 99

Code: NCT06898450·Phase 1, Phase 2·Recruiting

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NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

10 locations incl. Huntsville

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06911112·Phase 3·Recruiting

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Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy

for Miscarriage in First Trimester

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18 - 55

Code: NCT07088510·Recruiting

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A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

for Colitis Ulcerative

19 locations incl. Sun City

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06867094·Phase 2·Recruiting

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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

for Type 2 Diabetes

Drug: Semaglutide

25 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06897475·Phase 2·Recruiting

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

for Ulcerative Colitis

100 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 80

Code: NCT06581328·Phase 4·Recruiting

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Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for Metastatic Head and Neck Squamous Cell Carcinoma

177 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06589804·Phase 3·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

85 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06890598·Phase 3·Recruiting

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

60 locations incl. Tucson

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting

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CLOSM Trial: Groin Closure Using Layered Option for Suture Material

for Vascular Diseases

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT06990425·Recruiting

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Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for Advanced Solid Tumor

Drug: AI-081

19 locations incl. Birmingham

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06635785·Phase 1, Phase 2·Recruiting

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

55 locations incl. Bakersfield

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting

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Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

for Graft Vs Host Disease

3 locations incl. Tampa

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT06450925·Phase 2·Recruiting

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Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

for Acute Stress Reaction

9 locations incl. Birmingham

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 55

Code: NCT06636786·Phase 2·Recruiting

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ALPCO Calprotectin CLIA Assay - Measurement of Calprotectin Levels in Human Stool

for Inflammatory Bowel Disease (Crohn&#39

3 locations incl. Miami

Sponsor: American Laboratory Products Company

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT06810518·Recruiting

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A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for HR+ Breast Cancer

14 locations incl. La Jolla

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07029399·Phase 1·Recruiting

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Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for Non Small Cell Lung Cancer

15 locations incl. Scottsdale

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06810544·Phase 1, Phase 2·Recruiting

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A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors

for Triple Negative Locally Advanced Non-resectable Breast Cancer

6 locations incl. Los Angeles

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06827613·Phase 1, Phase 2·Recruiting

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A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair

for Peripheral Nerve Injuries

6 locations incl. San Francisco

Sponsor: Auxilium Biotechnologies

Sex: All·Age: 18 - 80

Code: NCT06529835·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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A Study of Navenibart in Participants With Hereditary Angioedema

for Hereditary Angioedema (HAE)

Drug: navenibart

19 locations incl. Birmingham

Sponsor: Astria Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06842823·Phase 3·Enrolling By Invitation

Studying the Health Perceptions and Social Behaviors of Graduate Students at the Ohio State University for the Development of Effective Oral Nicotine Pouch Addictive Risk Communication

for Tobacco-Related Carcinoma

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07346092·Recruiting

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Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for Ovarian Cancer

Drug: Bevacizumab

28 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: Female·Age: 18+

Code: NCT06819007·Phase 3·Recruiting

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A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for Psoriasis

Drug: Tirzepatide

40 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06857942·Phase 4·Recruiting

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Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents

for Bipolar Disorder (BD)

4 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 12 - 21

Code: NCT06920940·Recruiting

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

27 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting

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Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for Relapsed/Refractory KMT2A-r Acute Leukemia

11 locations incl. Los Angeles

Sponsor: PedAL BCU, LLC

Sex: All·Age: 0 - 21

Code: NCT06376162·Phase 1·Recruiting

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Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

for Bradycardia

7 locations incl. Avondale

Sponsor: VDI Technologies

Sex: All·Age: 18+

Code: NCT06641362·Recruiting

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Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

6 locations incl. Boston

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

for Chronic Obstructive Pulmonary Disease (COPD)

67 locations incl. Foley

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06883305·Phase 3·Recruiting

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An Open-Label Study of Azetukalner in Major Depressive Disorder

for Major Depressive Disorder

63 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06922110·Phase 3·Enrolling By Invitation

Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

31 locations incl. Tucson

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07032662·Phase 2·Recruiting

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A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

for Plasma Cell Myeloma Refractory

34 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06356571·Phase 2·Recruiting

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Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies

for Solid Tumor

2 locations incl. Columbus

Sponsor: Jabez Bioscience, Inc

Sex: All·Age: 18+

Code: NCT06801002·Phase 1·Recruiting

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

16 locations incl. Gilbert

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting

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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

92 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting

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Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

194 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting

Apply to this trial