Paid Clinical Trials in Ohio

Ohio has 3,476 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,476 clinical trials

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

13 locations incl. Phoenix

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting

Apply to this trial

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

39 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting

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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for Alzheimers Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07177352·Phase 3·Recruiting

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AI-Augmented Motivational Interviewing Training for Primary Care

for Multiple Chronic Conditions

2 locations incl. Dayton

Sponsor: Wright State University

Sex: All·Age: 21+

Code: NCT06597123·Not Yet Recruiting

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for Prostate Cancer

25 locations incl. Palo Alto

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06855277·Phase 3·Recruiting

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Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

for Preterm Delivery

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 14+·Accepts healthy volunteers

Code: NCT06980025·Phase 3·Recruiting

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Engaging Mental Health Services for Preschoolers at Risk

for Mental Health Disorder

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18+

Code: NCT07054554·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion Alone or in Combination With Oral, IV, Subcutaneous Daratumumab; Lenalidomide; Dexamethasone; Carfilzomib

for Multiple Myeloma

Drug: Daratumumab

8 locations incl. Denver

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06892522·Phase 1, Phase 2·Recruiting

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A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

for Breast Neoplasms

53 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06966700·Phase 3·Recruiting

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Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

for Colorectal Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07044362·Recruiting

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E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

332 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting

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The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

12 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting

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Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

for Atrial Fibrillation (AF)

12 locations incl. Jonesboro

Sponsor: Vektor Medical

Sex: All·Age: 22+

Code: NCT06935591·Recruiting

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A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function

for Semen Quality

4 locations incl. North Hollywood

Sponsor: ReproNovo Aps

Sex: Male·Age: 18 - 49

Code: NCT06993155·Phase 2·Recruiting

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

28 locations incl. Homewood

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

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A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

49 locations incl. Birmingham

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 12+

Code: NCT07007637·Phase 3·Enrolling By Invitation

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

37 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting

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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

35 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting

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Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

Drug: Empagliflozin

3 locations incl. Baltimore

Sponsor: Gustavo A Heresi, MD, MS

Sex: All·Age: 18+

Code: NCT06992440·Phase 2·Enrolling By Invitation

Prospective, Open-label, Non-significant Risk, Multicenter Study Comparing the Polyp Detection of the Study Device to That of the Colonoscopy Reference

for Colonic Polyps

11 locations incl. Chula Vista

Sponsor: Capso Vision, Inc.

Sex: All·Age: 45 - 75

Code: NCT07089615·Recruiting

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A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

for Inflammatory Bowel Disease (IBD)

46 locations incl. Birmingham

Sponsor: Mirador Therapeutics, Inc.

Sex: All·Age: 18 - 80

Code: NCT07113522·Phase 2·Recruiting

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Improving Sleep Health Outcomes for Family Caregivers

for Family Caregivers

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07513246·Recruiting

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An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

for Colorectal Cancer

13 locations incl. Los Angeles

Sponsor: NGM Biopharmaceuticals, Inc

Sex: All·Age: 18+

Code: NCT07033026·Phase 2·Recruiting

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Evaluating the Real World Performance of an AI Based Lung Nodule Detection Tool

for Lung Nodule

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06597968·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor Malignancies

15 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06994806·Phase 1·Recruiting

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Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

for Allergy

56 locations incl. Birmingham

Sponsor: DBV Technologies

Sex: All·Age: 1 - 3

Code: NCT07003919·Phase 3·Recruiting

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Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

for Refractory Angina

1 location in Cincinnati

Sponsor: XyloCor Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT07048808·Phase 2·Recruiting

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Quantitative Ultrasound(DeepUSFF) vs MRI-PDFF for Liver Fat Assessment in MASLD

for Metabolic Dysfunction-Associated Steatotic Liver Disease

1 location in Boardman

Sponsor: Seoul National University Hospital

Sex: All·Age: 18+

Code: NCT07192159·Recruiting

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Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

for Nausea

12 locations incl. Scottsdale

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18+

Code: NCT06464926·Recruiting

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

149 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting

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Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)

for Hidradenitis Suppurativa

Drug: Ruxolitinib

59 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06959225·Phase 3·Recruiting

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A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: Pegcetacoplan

68 locations incl. Gilbert

Sponsor: Apellis Pharmaceuticals, Inc.

Sex: All·Age: 60+

Code: NCT07215390·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting

Apply to this trial

Cognitive Assessment Tools for Huntington's Disease.

for Huntington Disease

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 30 - 65

Code: NCT06546488·Recruiting

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Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)

for Aneurysm

10 locations incl. Tucson

Sponsor: Stryker Neurovascular

Sex: All·Age: 18 - 80

Code: NCT06872684·Recruiting

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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

52 locations incl. Peoria

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06972446·Phase 2·Recruiting

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Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma

for Cutaneous Sarcoma

3 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07007273·Phase 2·Recruiting

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A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

for Dystrophic Epidermolysis Bullosa

5 locations incl. Rancho Santa Margarita

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 6 Months+

Code: NCT07016750·Phase 3·Recruiting

Apply to this trial