Clinical Trials at Yale University

As of June 2026, 275 paid clinical trials are recruiting at Yale University, located at 310 CEDAR ST, 416A LAUDER HALL, NEW HAVEN, CT 06510-3218, phone (203) 785-6843 in New Haven, Connecticut. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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275 clinical trials at Yale University

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

61 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting

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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

59 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06329401·Phase 2·Recruiting

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Peru Decentralized HIV Care

for HIV

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05910268·Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

104 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

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A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for Low Grade Serous Ovarian Cancer

Drug: Avutometinib

38 locations incl. Phoenix

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT06072781·Phase 3·Recruiting

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

133 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting

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International Post-Stroke Epilepsy Research Repository

for Post Stroke Epilepsy

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06108102·Enrolling By Invitation

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

34 locations incl. Little Rock

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting

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Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping

for Moderate to Severe Asthma

3 locations incl. Scottsdale

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 75

Code: NCT06385236·Phase 4·Recruiting

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RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

21 locations incl. Orange

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting

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A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

for Ovarian Cancer

14 locations incl. Denver

Sponsor: OnCusp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06234423·Phase 1·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

490 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT04974671·Phase 2·Recruiting

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A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas

for Advanced Solid Tumors

4 locations incl. San Francisco

Sponsor: Antengene Biologics Limited

Sex: All·Age: 18+

Code: NCT06028373·Phase 1·Recruiting

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting

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Supporting Parents in Affirming Their Children's Experiences of Stigma

for Parent-Child Relations

3 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 15+

Code: NCT05919849·Phase 1·Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

536 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting

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The PEERLESS II Study

for Pulmonary Embolism

50 locations incl. Birmingham

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06055920·Recruiting

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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Investigating the Mu:Kappa Opioid Receptor Imbalance in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT05957159·EARLY_Phase 1·Recruiting

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

29 locations incl. Chandler

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

76 locations incl. Phoenix

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT05899608·Phase 3·Recruiting

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Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

237 locations incl. Little Rock

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 60+

Code: NCT05976763·Phase 3·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

for Plasma Cell Myeloma

397 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: All ages

Code: NCT05561387·Phase 3·Recruiting

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Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

for Advanced Malignant Solid Neoplasm

23 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05691491·Phase 1, Phase 2·Recruiting

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

955 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting

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Left vs Left Randomized Clinical Trial

for Heart Failure

57 locations incl. Gilbert

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting

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Empagliflozin in Patients With Cirrhosis and Ascites

for Cirrhosis

Drug: Empagliflozin

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05726032·Phase 2·Recruiting

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Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

for Depressive Disorder, Major

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 60

Code: NCT05915013·Phase 1·Recruiting

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A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial

for Acute Kidney Injury

9 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05805709·Recruiting

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A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

for Advanced or Metastatic Solid Tumor

6 locations incl. New Haven

Sponsor: Pliant Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06270706·Phase 1·Recruiting

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A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

31 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting

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Mechanisms of Diuretic Resistance in Heart Failure, Aim 2

for Heart Failure

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05753059·Phase 1·Recruiting

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Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors

for Malignant Neoplasm of Breast

7 locations incl. Duarte

Sponsor: Novian Health Inc.

Sex: Female·Age: 18+

Code: NCT03463954·Recruiting

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Expanding Medication-Assisted Therapies in Central Asia

for Opioid Use Disorder

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05579470·Recruiting

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Effects of Acute and Chronic Empagliflozin Heart Failure

for Heart Failure

Drug: Empagliflozin

2 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05553938·Phase 1·Recruiting

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Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

for HIV

2 locations incl. Birmingham

Sponsor: Yale University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05547048·Phase 4·Recruiting

Apply to this trial