Paid Clinical Trials in North Carolina

North Carolina has 2,930 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,930 clinical trials

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A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

for Erosive Esophagitis

1 location in Wilmington

Sponsor: Phathom Pharmaceuticals, Inc.

Sex: Female·Age: 15 - 50

Code: NCT06660342·Recruiting

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Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

for Myotonic Dystrophy

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07362875·Recruiting

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PREnatal Choline and Infant Outcomes Study

for Nutrition During Pregnancy

1 location in Greenville

Sponsor: East Carolina University

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07525193·Recruiting

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Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for Central Line Associated Blood Stream Infections (CLABSI)

17 locations incl. Los Angeles

Sponsor: CorMedix

Sex: All·Age: 18+

Code: NCT06822426·Phase 3·Recruiting

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A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for Atopic Dermatitis

22 locations incl. Fountain Valley

Sponsor: Apogee Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07003425·Phase 2·Recruiting

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A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

for Severe Hemophilia A

3 locations incl. Los Angeles

Sponsor: Pfizer

Sex: Male·Age: 12 - 74

Code: NCT06703606·Phase 1·Recruiting

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Multi-session Transcranial Alternating Current Stimulation to Improve Dual-task Standing and Brain Activity in Older Adults With Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

1 location in High Point

Sponsor: High Point University

Sex: All·Age: 65 - 85

Code: NCT07097051·Phase 2·Recruiting

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Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia

for Severe Aplastic Anemia

25 locations incl. Birmingham

Sponsor: Medical College of Wisconsin

Sex: All·Age: 3 - 75

Code: NCT06517641·Phase 2·Recruiting

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Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for Amyloidosis

Drug: Acoramidis

39 locations incl. La Jolla

Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All·Age: 18 - 75

Code: NCT06563895·Phase 3·Recruiting

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CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

for Type 1 Diabetes Mellitus

30 locations incl. Tucson

Sponsor: COUR Pharmaceutical Development Company, Inc.

Sex: All·Age: 12 - 35

Code: NCT06783309·Phase 1, Phase 2·Recruiting

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

50 locations incl. Glendale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819891·Phase 3·Recruiting

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COmmunities Aligned to Reduce Concussion and Head Impact Exposure

for Concussions

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 11 - 14·Accepts healthy volunteers

Code: NCT06624202·Recruiting

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Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.

for Diabetic Foot Ulcer

1 location in Monroe

Sponsor: Samaritan Biologics

Sex: All·Age: 18+

Code: NCT06437028·Recruiting

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Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

for Pancreatic Carcinoma

118 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06807437·Phase 3·Recruiting

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Mirikizumab Real World Protocol

for Ulcerative Colitis

8 locations incl. Denver

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT06696014·Recruiting

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Urine Methylation Markers in UTUC

for Upper Tract Urothelial Cancer

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06805630·Recruiting

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Improving Parental Support in Hypospadias Care

for Hypospadias

2 locations incl. Indianapolis

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: All ages

Code: NCT06832280·Recruiting

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndromes

23 locations incl. Duarte

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06499285·Phase 3·Recruiting

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A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

16 locations incl. Scottsdale

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06747351·Phase 3·Recruiting

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Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

for Myasthaenia Gravis

23 locations incl. Tucson

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT06799247·Phase 3·Recruiting

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Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

for NSCLC (Non-small Cell Lung Cancer)

Drug: daraxonrasib

39 locations incl. Birmingham

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06881784·Phase 3·Recruiting

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Tube Size Randomized Trial During Emergency Tracheal Intubation

for Acute Respiratory Failure

7 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06939361·Enrolling By Invitation

A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

for Narcolepsy Type 2

31 locations incl. Auburn

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06952699·Phase 2·Recruiting

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H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

for Interstitial Lung Disease

1 location in Research Triangle Park

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 18 - 100

Code: NCT06325696·Phase 2·Recruiting

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Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

for Inflammatory Bowel Disease (IBD)

6 locations incl. New Orleans

Sponsor: Mercy Medical Center

Sex: All·Age: 18+

Code: NCT06750731·Recruiting

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Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications

for Surgical Drain

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06916286·Recruiting

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WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

26 locations incl. Birmingham

Sponsor: Mediar Therapeutics

Sex: All·Age: 40+

Code: NCT06967805·Phase 2·Recruiting

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Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

for Epilepsy Intractable

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06545643·Recruiting

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Nutrition OUtReach In Systems of Healthcare

for ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

4 locations incl. Stanford

Sponsor: University of Kansas Medical Center

Sex: All·Age: 8 - 80

Code: NCT06802406·Recruiting

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A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

for Systemic Lupus Erythematosus

7 locations incl. Anniston

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT06916806·Phase 1·Recruiting

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Motiva Implants® Post-Approval Study

for Breast Implant

30 locations incl. Beverly Hills

Sponsor: Motiva USA LLC

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06938399·Recruiting

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Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

for Kidney Calculi

16 locations incl. Phoenix

Sponsor: Avvio Medical

Sex: All·Age: 21+

Code: NCT06942949·Recruiting

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A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

for Solid Tumor

11 locations incl. San Francisco

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06952010·Phase 1·Recruiting

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A Study to Train a Machine Learning Algorithm for an Evaluation of the Use of Biometric Data Captured at the Wrist for the Identification of Acute Opioid Use Events and the Quantification of Opioid Withdrawal in Opioid Dependent Individuals

for Treatment for Opioid Use Disorder

4 locations incl. Wilmington

Sponsor: OpiAID

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07405398·Recruiting

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Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

for Atherosclerotic Cardiovascular Disease (ASCVD)

Drug: Inclisiran

37 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT06813911·Phase 3·Recruiting

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IBD Pregnancy Registry

for Inflammatory Bowel Disease (IBD)

1 location in Wilmington

Sponsor: CorEvitas

Sex: Female·Age: 18 - 50

Code: NCT06910553·Recruiting

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A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

9 locations incl. Rancho Mirage

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06538064·Recruiting

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Project neuroARTEMIS

for Stimulant Use

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 59

Code: NCT06814275·Recruiting

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

49 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting

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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Lymphoma

Drug: Glofitamab

16 locations incl. La Jolla

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06624085·Phase 1·Recruiting

Apply to this trial