Paid Clinical Trials in Naples, FL

As of June 2026, 103 paid clinical trials are recruiting in Naples, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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103 clinical trials

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

86 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting

Apply to this trial

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

for Soft Tissue Lesion

10 locations incl. Gilbert

Sponsor: Galvanize Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05851430·Recruiting

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Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

55 locations incl. Sheffield

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 80

Code: NCT06961214·Phase 3·Recruiting

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RESTORE TRIAL: A Phase 2 Study Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)

for Alcohol Liver Disease

Drug: Pemvidutide

42 locations incl. Peoria

Sponsor: Altimmune, Inc.

Sex: All·Age: 18 - 75

Code: NCT07009860·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for Multiple Sclerosis Spasticity

15 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18 - 70

Code: NCT06782490·Phase 2·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

32 locations incl. Mobile

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting

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Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

for Cervical Cancer

92 locations incl. Phoenix

Sponsor: Pfizer

Sex: Female·Age: 18+

Code: NCT06952660·Phase 4·Recruiting

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A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

for Parkinson Disease

Drug: LY4006896

12 locations incl. Los Alamitos

Sponsor: Eli Lilly and Company

Sex: All·Age: 30 - 85·Accepts healthy volunteers

Code: NCT06809400·Phase 1·Recruiting

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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

66 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting

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A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

19 locations incl. La Jolla

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06227910·Phase 3·Recruiting

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Patients With Congenital Myasthenic Syndrome Will be Treated With Mesenchymal Stem Cell Exosome Solution

for Congenital Myasthenic Syndrome

2 locations incl. Naples

Sponsor: The Foundation for Orthopaedics and Regenerative Medicine

Sex: All·Age: 18+

Code: NCT07226726·Phase 1·Recruiting

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Efficacy and Safety of Leadless Pacemakers Versus Left Bundle Area Pacing - A Preliminary Exploration

for Pacemaker Implantation

2 locations incl. Naples

Sponsor: NCH Healthcare System, Inc. dba Naples Comprehensive Health and dba NCH

Sex: All·Age: 18+

Code: NCT06690333·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

153 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

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A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

for Alzheimer Disease

Drug: LY4006895

11 locations incl. Los Alamitos

Sponsor: Eli Lilly and Company

Sex: All·Age: 45 - 85·Accepts healthy volunteers

Code: NCT06657768·Phase 1·Recruiting

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J-Valve Transfemoral Pivotal Study

for Aortic Valve Regurgitation

34 locations incl. Scottsdale

Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC

Sex: All·Age: 18+

Code: NCT06455787·Recruiting

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A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for Alzheimer Disease

Drug: KarXT

98 locations incl. Chandler

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT06585787·Phase 3·Recruiting

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LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

for Metabolic Dysfunction Associated Steatohepatitis (MASH)

Drug: Survodutide

165 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06632444·Phase 3·Recruiting

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Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

for Heart Failure With Preserved Ejection Fraction

8 locations incl. Naples

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 18+

Code: NCT05839730·Recruiting

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A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for Lung Diseases, Interstitial

16 locations incl. Los Angeles

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06572384·Phase 3·Recruiting

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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

168 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting

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LMN-201 for Prevention of C. Difficile Infection Recurrence

for Clostridioides Difficile Infection

16 locations incl. Escondido

Sponsor: Lumen Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05330182·Phase 2, Phase 3·Recruiting

Apply to this trial

SuperSaturated Oxygen Comprehensive Observational Registry

for STEMI - ST Elevation Myocardial Infarction

25 locations incl. Fountain Valley

Sponsor: TherOx

Sex: All·Age: 18 - 80

Code: NCT06438315·Recruiting

Apply to this trial

Endocardial Mapping With the CoreMap EP Mapping System

for Persistent Atrial Fibrillation

2 locations incl. Naples

Sponsor: CoreMap Inc.

Sex: All·Age: 18 - 80

Code: NCT06529978·Recruiting

Apply to this trial

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

for Depressive Disorder, Major

Drug: Seltorexant

84 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT06559306·Phase 3·Recruiting

Apply to this trial

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

87 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting

Apply to this trial

A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

for Atrial Fibrillation

43 locations incl. Phoenix

Sponsor: Biosense Webster, Inc.

Sex: All·Age: 18 - 80

Code: NCT06455098·Recruiting

Apply to this trial

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

for Heart Failure

Drug: Empagliflozin

95 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06424288·Phase 3·Recruiting

Apply to this trial

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

84 locations incl. Huntsville

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting

Apply to this trial

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

for Cerebral Amyloid Angiopathy

34 locations incl. Los Angeles

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 30+

Code: NCT06393712·Phase 2·Recruiting

Apply to this trial

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

for Atrial Fibrillation

7 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06436924·Recruiting

Apply to this trial

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for Aortic Stenosis

Drug: Pelacarsen

37 locations incl. Huntsville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 80

Code: NCT05646381·Phase 2·Recruiting

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

29 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting

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The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

for Paroxysmal Atrial Fibrillation

21 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06324201·Recruiting

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

234 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

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Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

53 locations incl. Sun City

Sponsor: Gilead Sciences

Sex: All·Age: 18 - 75

Code: NCT06029972·Phase 2·Recruiting

Apply to this trial

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for NASH With Fibrosis

Drug: Efruxifermin

205 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06215716·Phase 3·Recruiting

Apply to this trial

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for Aortic Valve Insufficiency

32 locations incl. Newport Beach

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172973·Recruiting

Apply to this trial