Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

for Major Depressive Disorder

25 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06705478·Phase 2·Recruiting

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Metacognitive Strategy Training Intervention for Transition-Age Youth With Cerebral Palsy

for Cerebral Palsy (CP)

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 13 - 17

Code: NCT07424079·Not Yet Recruiting

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

for Smoking

7 locations incl. Maitland

Sponsor: RAI Services Company

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07598136·Recruiting

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Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

for Ovarian Cancer

5 locations incl. Peoria

Sponsor: Nerviano Medical Sciences

Sex: Female·Age: 18+

Code: NCT06930755·Phase 1·Recruiting

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Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for Locally Advanced Pancreatic Adenocarcinoma

274 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06998940·Phase 3·Recruiting

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A Feasibility Trial of Virtual Reality Neurofeedback for Adolescents With Migraine

for Migraine

1 location in Kansas City

Sponsor: Children's Mercy Hospital Kansas City

Sex: All·Age: 10 - 16

Code: NCT07454798·Recruiting

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Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

14 locations incl. Sacramento

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: INCA036978

22 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting

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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

115 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting

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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

202 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Not Yet Recruiting

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

for Overweight

48 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07575932·Phase 2·Recruiting

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A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for Major Depressive Disorder

27 locations incl. Gilbert

Sponsor: Definium Therapeutics US, Inc.

Sex: All·Age: 18 - 74

Code: NCT07592689·Phase 3·Recruiting

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Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis

for Liver Fibrosis

19 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07610837·Phase 2·Recruiting

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Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

3 locations incl. St Louis

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07427394·Phase 2·Recruiting

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Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

12 locations incl. Springdale

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting

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Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy

for Hypertrophic Cardiomyopathy (HCM)

Drug: Mavacamten

2 locations incl. Kansas City

Sponsor: Oregon Health and Science University

Sex: All·Age: 18 - 90

Code: NCT07600177·Phase 4·Recruiting

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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

for Colitis, Ulcerative

15 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483073·Phase 2·Recruiting

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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

for Crohn Disease

Drug: LY4395089

15 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483099·Phase 2·Recruiting

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A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults

for COVID-19

6 locations incl. Decatur

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07536308·Phase 1·Recruiting

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Intrathecal Ziconotide in Chemotherapy Induced Peripheral Neuropathy

for Chemotherapy Induced Peripheral Neuropathy (CIPN)

1 location in St Louis

Sponsor: Christian Hospital Northeast Northwest

Sex: All·Age: 18 - 100

Code: NCT07499882·Not Yet Recruiting

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

for Acute Ischemic Stroke

6 locations incl. Chicago

Sponsor: Amrou Sarraj

Sex: All·Age: 18 - 85

Code: NCT07115940·Recruiting

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Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

16 locations incl. Orange

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting

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Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

Improving Cancer Prevention and Control Through Academic-local Public Health Department Partnerships

for Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06605196·Not Yet Recruiting

Horizon Two: HR NDMM (MMRC-100)

for High Risk Newly Diagnosed Multiple Myeloma

7 locations incl. Atlanta

Sponsor: Multiple Myeloma Research Consortium

Sex: All·Age: 18+

Code: NCT07053436·Phase 2·Recruiting

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A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults

for Hearing Loss, Bilateral Sensorineural

11 locations incl. Englewood

Sponsor: Cochlear

Sex: All·Age: 18+

Code: NCT07287124·Recruiting

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52-week Open Label Safety-Tolerability Study

for Schizophrenia

23 locations incl. Chandler

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07369154·Phase 3·Not Yet Recruiting

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

4 locations incl. Atlanta

Sponsor: Dyne Therapeutics

Sex: All·Age: 16+

Code: NCT07486934·Phase 3·Recruiting

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A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for Patient-Reported Outcome Measures (PROMs)

14 locations incl. Stanford

Sponsor: Carelon Research

Sex: All·Age: 12 - 17

Code: NCT07525843·Recruiting

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A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females

for Iron Deficiencies

1 location in Saint Charles

Sponsor: Lindenwood University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07546591·Recruiting

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Talar Osteochondral Lesions With Pilon Fractures

for Pilon Fractures

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT07553221·Not Yet Recruiting

BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease

for Congenital Heart Disease (CHD)

8 locations incl. Phoenix

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582848·Not Yet Recruiting

Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

for Congenital Heart Disease (CHD)

17 locations incl. Phoenix

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582861·Not Yet Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

51 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07195734·Phase 2·Recruiting

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The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.

for Spine Surgery

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 79

Code: NCT07365800·Phase 4·Enrolling By Invitation

PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

13 locations incl. Scottsdale

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting

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Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis

for Atherosclerosis Cardiovascular Disease

4 locations incl. Beverly Hills

Sponsor: Atom Therapeutics Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07303777·Phase 2·Recruiting

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Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia

for Hypochondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT07393373·Phase 2·Enrolling By Invitation

Donidalorsen Treatment in Children With Hereditary Angioedema

for Hereditary Angioedema (HAE)

5 locations incl. Santa Monica

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 11

Code: NCT07298447·Phase 3·Recruiting

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5-Fluorouracil Response and Optimization STudy (The FROST Trial)

for Squamous Cell Carcinoma of Head and Neck

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07419464·Phase 2·Recruiting

Apply to this trial