Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

for Adenoid Cystic Carcinoma

8 locations incl. Boston

Sponsor: Rgenta Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06462183·Phase 1·Recruiting

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Intensive Pediatric Group Intervention

for Cerebral Palsy

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 7 - 17

Code: NCT06527469·Enrolling By Invitation

Empagliflozin Reversal of Arterial StiffnEss in Aging

for Aging

Drug: Empagliflozin

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 60 - 80·Accepts healthy volunteers

Code: NCT06506422·Phase 2, Phase 3·Recruiting

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Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for B-cell Acute Lymphoblastic Leukemia

17 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 6 Months - 25

Code: NCT06395103·Phase 1, Phase 2·Recruiting

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Promoting Improved Functioning Among People Experiencing Stressful Situations

for Acute Stress Reaction

5 locations incl. Belmont

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 50

Code: NCT06482567·Recruiting

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Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

for Metastatic Pancreatic Neuroendocrine Tumor

9 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687123·Phase 1·Recruiting

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A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

101 locations incl. Birmingham

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting

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Study to Understand Novel Biomarkers in Researching Dementia

for Alzheimer Disease

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06547099·Recruiting

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A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

for Metastatic HER2-positive Breast Cancer

48 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06435429·Phase 3·Recruiting

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Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for Biliary Tract Cancer

Drug: Rilvegostomig

48 locations incl. Scottsdale

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT06467357·Phase 3·Recruiting

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Efficacy and Safety of a Ketogenic Diet in Type 1 Diabetes

for Diabetes Mellitus, Type 1

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 65

Code: NCT06503809·Recruiting

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Thrive Intervention in Schools

for Childhood Mental Disorder

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 3 - 7

Code: NCT06139874·Enrolling By Invitation

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

266 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting

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A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

51 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting

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A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)

for Septic Shock

6 locations incl. Chandler

Sponsor: Vivacelle Bio

Sex: All·Age: 18+

Code: NCT06072430·Phase 3·Recruiting

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Study of XB010 in Subjects With Solid Tumors

for Locally Advanced or Metastatic Solid Tumors

15 locations incl. Irvine

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06545331·Phase 1·Recruiting

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Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)

for PSMA PET-Positive Castration-Resistant Prostate Cancer

9 locations incl. San Diego

Sponsor: Convergent Therapeutics

Sex: Male·Age: 18+

Code: NCT06549465·Phase 2·Recruiting

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A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

32 locations incl. Tucson

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06428019·Phase 3·Recruiting

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Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

7 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT06544798·Phase 2·Enrolling By Invitation

Feasibility and Success Trial of Remote Patient Monitoring in Heart Failure

for Congestive Heart Failure

4 locations incl. Kansas City

Sponsor: Saint Luke's Health System

Sex: All·Age: 18 - 80

Code: NCT05900362·Not Yet Recruiting

TruGraf Liver Gene Expression Serial Test

for Autoimmune Liver Disease

2 locations incl. St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06061341·Enrolling By Invitation

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

for Head and Neck Squamous Cell Carcinoma

29 locations incl. Duarte

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06163534·Recruiting

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Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

for Obesity

1 location in Columbia

Sponsor: Bettina Mittendorfer

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06335771·Recruiting

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Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

54 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06380751·Phase 3·Recruiting

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DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for Gestational Diabetes Mellitus

21 locations incl. Tuscaloosa

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT06445946·Phase 4·Recruiting

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Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

for Excessive Sleepiness

Drug: Solriamfetol

38 locations incl. Cullman

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06568367·Phase 3·Recruiting

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Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

for Obesity

1 location in Columbia

Sponsor: Bettina Mittendorfer

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06571474·Recruiting

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Remote Sensing for ADRD-Specific Activities Identification in Older Adults

for Alzheimer Disease and Related Dementias (ADRD)

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07120347·Recruiting

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A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

for Advanced Solid Tumor

11 locations incl. Irvine

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06147037·Phase 1·Recruiting

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LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for Metastatic Non-small Cell Lung Cancer

35 locations incl. Birmingham

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06216301·Phase 3·Recruiting

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Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

for Acute Ischemic Stroke

15 locations incl. Scottsdale

Sponsor: Basking Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06226805·Phase 2·Recruiting

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Long-term Safety and Tolerability of BHV-7000

for Focal Epilepsy

115 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06443463·Phase 2·Enrolling By Invitation

Investigations of Reproductive Cancers in Women

for Uterine Cancer

16 locations incl. Birmingham

Sponsor: PinkDx, Inc.

Sex: Female·Age: 45 - 100

Code: NCT06527157·Recruiting

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A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

for Recurrent Ovarian Cancer

12 locations incl. Los Angeles

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06365853·Phase 2·Recruiting

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Embedded Palliative Care in the MICU

for Critical Illness

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06574672·Recruiting

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The APS Phenotyping Study

for ARDS

20 locations incl. Fresno

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06521502·Recruiting

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Study of Enhanced Programming Stimulation with the Enterra® Therapy System

for Gastroparesis

6 locations incl. Tampa

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18 - 70

Code: NCT06560307·Recruiting

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

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PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

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Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for Clinical Stage III Cutaneous Melanoma AJCC v8

26 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05896839·Phase 1, Phase 2·Recruiting

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