Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for Solid Tumors

7 locations incl. Denver

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT06386146·Phase 1, Phase 2·Recruiting

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TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

for Tricuspid Regurgitation

36 locations incl. Phoenix

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18+

Code: NCT06137807·Recruiting

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ECMO ABI Detection With Hyperfine

for Acute Brain Injury

1 location in Kansas City

Sponsor: Children's Mercy Hospital Kansas City

Sex: All·Age: 0 Days - 17

Code: NCT06469801·Recruiting

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Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

2 locations incl. St Louis

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT06179303·Phase 2·Recruiting

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A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

for Cancer

6 locations incl. Los Angeles

Sponsor: Angiex, Inc.

Sex: All·Age: 18+

Code: NCT06440005·Phase 1·Recruiting

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Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

for Advanced Lung Non-Small Cell Carcinoma

318 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 70+

Code: NCT06096844·Phase 3·Recruiting

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PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

13 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting

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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

for Inflammatory Bowel Diseases

25 locations incl. Lancaster

Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Sex: All·Age: 18 - 85

Code: NCT06226883·Phase 2·Recruiting

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A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

17 locations incl. Irvine

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting

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Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for Metastatic Colorectal Cancer

Drug: Bevacizumab

26 locations incl. Chandler

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT06252649·Phase 3·Recruiting

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Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

for Metastatic Nasopharyngeal Carcinoma

Drug: Relatlimab

83 locations incl. Dublin

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06029270·Phase 2·Recruiting

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A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

for Hepatocellular Carcinoma

Drug: Atezolizumab

60 locations incl. Tucson

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06096779·Phase 2·Recruiting

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Galleri® in the Medicare Population.

for Cancer

61 locations incl. Fort Smith

Sponsor: GRAIL, Inc.

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT05673018·Recruiting

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A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Drug: riliprubart

27 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290128·Phase 3·Recruiting

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

29 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting

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Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity

for Spasticity, Cerebral or Spinal Condition

18 locations incl. Downey

Sponsor: Pacira Pharmaceuticals, Inc

Sex: All·Age: 18+

Code: NCT06340451·Recruiting

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Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery

for Resectable Intrahepatic Cholangiocarcinoma

Drug: Durvalumab

58 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06050252·Phase 2·Recruiting

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Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients

for Brain Tumor, Primary

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 8 - 21

Code: NCT06185686·Recruiting

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A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF)

for Heart Failure

Drug: Finerenone

8 locations incl. Fairhope

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06024746·Phase 3·Recruiting

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Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

for Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

22 locations incl. Los Angeles

Sponsor: Servier Bio-Innovation LLC

Sex: All·Age: 18+

Code: NCT06127407·Phase 3·Recruiting

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Continuation Protocol for Obstructive Sleep Apnea (OSA)

for OSA

93 locations incl. Birmingham

Sponsor: Apnimed

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06566820·Phase 3·Enrolling By Invitation

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

117 locations incl. Goodyear

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting

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Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

for Spinal Fusion

1 location in Kansas City

Sponsor: Nichole Doyle

Sex: All·Age: 10 - 21·Accepts healthy volunteers

Code: NCT06067893·Phase 4·Enrolling By Invitation

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

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LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment

for Syphilis Infection

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06391125·Phase 3·Recruiting

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

17 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting

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CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

for Trauma

15 locations incl. Tucson

Sponsor: Jason Sperry

Sex: All·Age: 18 - 90

Code: NCT05958342·Phase 2·Recruiting

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Global Paradise System US Post Approval Study

for Hypertension

39 locations incl. Sacramento

Sponsor: ReCor Medical, Inc.

Sex: All·Age: 18+

Code: NCT06297291·Recruiting

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A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

for Carcinoma, Pancreatic Ductal

26 locations incl. Fayetteville

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06447662·Phase 1·Recruiting

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

101 locations incl. Phoenix

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting

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TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

for Cancer

31 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT06207032·Recruiting

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

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ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

for Cardiovascular Risk

Drug: Ziltivekimab

208 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06118281·Phase 3·Recruiting

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No DIET Trial: Dogmatic Interruption of Enteral nuTrition

for Gastrostomy

1 location in Columbia

Sponsor: Jeffrey Coughenour

Sex: All·Age: 18+

Code: NCT06431048·Enrolling By Invitation

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for Transthyretin Amyloidosis

30 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06465810·Recruiting

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A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

61 locations incl. Mobile

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06496178·Phase 3·Recruiting

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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

for Stroke

13 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05907629·Recruiting

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Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

371 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06203600·Phase 2, Phase 3·Recruiting

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Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for Triple-Negative Breast Cancer

88 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06393374·Phase 3·Recruiting

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Early Intervention to Promote Cardiovascular Health of Mothers and Children

for Cardiovascular Health

9 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06272045·Recruiting

Apply to this trial