Paid Clinical Trials in Missouri

Missouri has 2,061 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,061 clinical trials

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Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

for Spinal Cord Injury

7 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06529094·Recruiting

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Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

for Diabetic Nephropathies

Drug: Sotagliflozin

13 locations incl. Stanford

Sponsor: Alessandro Doria

Sex: All·Age: 18 - 75

Code: NCT06217302·Phase 3·Recruiting

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Cognitive Rehabilitation Following Breast Cancer Treatment

for Breast Cancer Female

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 20 - 75

Code: NCT06545045·Recruiting

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

20 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

152 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

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The Role of Circadian Clock Proteins in Innate and Adaptive Immunity

for Pneumonia

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 65

Code: NCT03482245·Recruiting

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Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

19 locations incl. Duarte

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting

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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

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Uterine Preservation Via Lifestyle Transformation

for Endometrial Hyperplasia

3 locations incl. St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT05903131·Phase 2·Recruiting

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Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for Classic Follicular Lymphoma

Drug: Mosunetuzumab

267 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06337318·Phase 3·Recruiting

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A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

for Primary Myelofibrosis

13 locations incl. Palo Alto

Sponsor: Ajax Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06343805·Phase 1·Recruiting

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

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Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

58 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting

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A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for Carcinoma, Non-Small-Cell Lung

Drug: Intismeran autogene

48 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06623422·Phase 3·Recruiting

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Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

25 locations incl. Cullman

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06619860·Phase 2·Recruiting

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

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J-Valve Transfemoral Pivotal Study

for Aortic Valve Regurgitation

34 locations incl. Scottsdale

Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC

Sex: All·Age: 18+

Code: NCT06455787·Recruiting

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Laser In Situ Fenestration Study

for Aortic Aneurysm

1 location in Columbia

Sponsor: Jonathan Bath

Sex: All·Age: 18+

Code: NCT06411990·Recruiting

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Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy

for Pediatric Disorder

1 location in Kansas City

Sponsor: Children's Mercy Hospital Kansas City

Sex: All·Age: 5 - 17

Code: NCT06554288·Phase 1·Recruiting

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Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression

for Infertility

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 18+

Code: NCT06636838·Recruiting

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Nasal Obstruction With Oxymetazoline and Corticosteroids

for Nasal Obstruction

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06830109·Phase 2·Recruiting

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Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

for Hematopoietic and Lymphatic System Neoplasm

30 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06279013·Recruiting

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Focused Acceptance and Commitment Therapy (FACT)

for Pediatric Feeding Disorders

1 location in Kansas City

Sponsor: Children's Mercy Hospital Kansas City

Sex: All·Age: 18+

Code: NCT06630000·Recruiting

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

19 locations incl. Phoenix

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting

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Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

for Clonal Cytopenia of Undetermined Significance

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06240754·Phase 2·Recruiting

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A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for Non-small Cell Lung Cancer

Drug: Relatlimab

45 locations incl. Mobile

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06561386·Phase 3·Recruiting

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A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

34 locations incl. Fayetteville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06417814·Phase 3·Recruiting

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Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

for Acute Respiratory Distress Syndrome

15 locations incl. Irvine

Sponsor: BioAegis Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05947955·Phase 2·Recruiting

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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for Hypertension

33 locations incl. Birmingham

Sponsor: SoniVie Inc.

Sex: All·Age: 22 - 75

Code: NCT06559891·Recruiting

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Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

for Pediatric Recurrent Central Nervous System Tumors

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: Up to 25

Code: NCT03988283·Phase 1·Recruiting

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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

for Peripheral T-Cell Lymphoma, Not Otherwise Specified

Drug: Soquelitinib

21 locations incl. Duarte

Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06561048·Phase 3·Recruiting

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NeuroControl of Nicotine Dependence

for Nicotine Dependence

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06347055·Recruiting

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Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Intermediate Risk Non-Muscle Invasive Bladder Cancer

Drug: Nadofaragene Firadenovec

49 locations incl. Mobile

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06510374·Phase 3·Recruiting

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Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria

for Phenylketonurias

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 10 - 17

Code: NCT06560736·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

76 locations incl. Anniston

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting

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Preterm Infants Fed a Human Milk Fortifier

for Growth

14 locations incl. Phoenix

Sponsor: Abbott Nutrition

Sex: All·Age: All ages

Code: NCT05551975·Not Yet Recruiting

Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma

for Asthma

Drug: Lunsekimig

27 locations incl. Chandler

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06609239·Phase 2·Enrolling By Invitation

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

11 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

221 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting

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Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

37 locations incl. Baltimore

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting

Apply to this trial