Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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CE-STAND: Cervical Epidural STimulation After Neurologic Damage

for Spinal Cord Injury

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT06410001·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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Long-Term Open-Label Extension Study of Oral Levosimendan

for Pulmonary Hypertension Associated With HFpEF

5 locations incl. Chicago

Sponsor: Tenax Therapeutics, Inc.

Sex: All·Age: All ages

Code: NCT07436689·Phase 3·Enrolling By Invitation

MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial

for Adult Obesity

Drug: Semaglutide

15 locations incl. Birmingham

Sponsor: Eccogene

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07505303·Phase 2·Not Yet Recruiting

A Standardized Counseling Approach to Preoperative Education in Transmasculine Individuals Receiving Gender-affirming Surgery

for Hysterectomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07324967·Recruiting

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A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects

for Exocrine Pancreatic Insufficiency

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07285863·Phase 4·Recruiting

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Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting

for Respiratory Distress Syndrome, Newborn

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 32 Weeks - 41 Weeks·Accepts healthy volunteers

Code: NCT07344714·Recruiting

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A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for Type 1 Diabetes

Drug: Adalimumab

11 locations incl. San Francisco

Sponsor: City of Hope Medical Center

Sex: All·Age: 9 - 20

Code: NCT07061574·Phase 1, Phase 2·Recruiting

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A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

9 locations incl. Mobile

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218341·Phase 4·Recruiting

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A Study Of Heart Disease Using AI-Enabled Electrocardiography And Focused Cardiac Ultrasound

for Heart Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 15+

Code: NCT07351656·Recruiting

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A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure

for Lyme Disease

19 locations incl. Pikesville

Sponsor: Tarsus Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07562087·Phase 2·Recruiting

Apply to this trial

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

52 locations incl. Tucson

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting

Apply to this trial

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

for Spinal Cord Injuries

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07210411·Recruiting

Apply to this trial

Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

for Persistent Post Concussion Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07246993·Recruiting

Apply to this trial

Clinical Decision Support With Continuous Glucose Monitoring Data for Managing Type 2 Diabetes

for Type 2 Diabetes

1 location in Minneapolis

Sponsor: HealthPartners Institute

Sex: All·Age: 18 - 75

Code: NCT07394075·Enrolling By Invitation

A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses

for Moral Injury

3 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT07455370·Enrolling By Invitation

Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling

for Chronic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07103135·Phase 1·Recruiting

Apply to this trial

Assessing Immune Dysfunction in Sepsis

for Sepsis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07154615·Recruiting

Apply to this trial

Steroid Treatment for Severe Acute Respiratory Infection (STAR) Trial

for Hypoxemia

1 location in Minneapolis

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT07199192·Phase 4·Not Yet Recruiting

Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

1 location in Brooklyn Park

Sponsor: Airiver Medical, Inc.

Sex: All·Age: 18+

Code: NCT07290140·Not Yet Recruiting

The Black Immigrant Project

for Dementia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07546708·Recruiting

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A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

for Liver Cirrhosis

Drug: BI 3802876

26 locations incl. Chandler

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 75

Code: NCT07325526·Phase 2·Recruiting

Apply to this trial

Percept Transitions in FOG and PD

for Freezing of Gait

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75

Code: NCT06848205·Recruiting

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Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy

for Autoimmune Disorders

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT07103746·Phase 2·Recruiting

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Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for Advanced Hepatocellular Carcinoma

107 locations incl. Berkeley

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT07166406·Phase 3·Recruiting

Apply to this trial

A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation

for Cardiomyopathy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07308704·Recruiting

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Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

for Schizophrenia

Drug: KarXT

45 locations incl. Bryant

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07379827·Recruiting

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Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

for Relapsed Small Cell Lung Cancer

11 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06681220·Phase 1, Phase 2·Recruiting

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A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

for Catecholaminergic Polymorphic Ventricular Tachycardia

4 locations incl. Boston

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 7+

Code: NCT07148089·Phase 1·Recruiting

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A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

48 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting

Apply to this trial

Evaluation of a Novel Drain Stripping Device for Reducing Surgical Drain Complications

for Surgical Drain

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07119112·Enrolling By Invitation

Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury

for Spinal Cord Injury

1 location in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 18 - 84

Code: NCT07384052·Phase 1·Recruiting

Apply to this trial

Enhancing Brain And Mental Health Through Breathing Practice

for Depressive Disorder

2 locations incl. Albert Lea

Sponsor: Mayo Clinic

Sex: All·Age: 12 - 17

Code: NCT07369752·Recruiting

Apply to this trial

A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis

for Neurotrophic Keratitis

3 locations incl. Carmel

Sponsor: TearSolutions, Inc.

Sex: All·Age: 18+

Code: NCT07568730·Phase 2·Recruiting

Apply to this trial

Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

for Post Traumatic Stress Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18 - 40

Code: NCT07485231·Recruiting

Apply to this trial

RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)

for Unipolar Depression

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 65

Code: NCT07266545·Phase 4·Recruiting

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The Effect of Centralization on Medial Meniscal Extrusion for Medial Meniscus Posterior Root Tear Repair

for Meniscus Tear

3 locations incl. West Vail

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 65

Code: NCT07388290·Enrolling By Invitation

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

for Pancreatic Cancer

14 locations incl. Fullerton

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07409272·Phase 3·Recruiting

Apply to this trial

Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

for Breast Cancer

2 locations incl. Rochester

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07340541·Phase 2·Recruiting

Apply to this trial

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy

18 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07210723·Phase 2, Phase 3·Recruiting

Apply to this trial