Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT07485231
Status
Recruiting

Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 40 Years
Healthy Volunteers
Not accepted

Interventions

  • Beetroot Juice — DIETARY_SUPPLEMENT
    We will use James White Beet It sports shot (70ml), which contains 400 mg of dietary nitrate
  • Placebo Juice — DIETARY_SUPPLEMENT
    James White Nitrate Depleted Placebo ( 70 ml) will be used as a placebo

Study Details

This research study is conducted to better understand why women with post-traumatic stress disorder (PTSD) have higher risk of cardiovascular disease as they get older. This study looks at how trauma and PTSD affect blood vessels in young women by testing whether the dietary supplement beetroot juice might help improve the function of blood vessels in women suffering from PTSD.

Key Dates

Start date
Feb 18, 2026
Status verified
Apr 2026
Primary completion
May 1, 2028
Completion
May 1, 2028

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Beetroot Juice
  • Placebo Comparator: Placebo Juice

Primary Outcome Measure

Change in Flow Mediated Dilation (FMD) [ Time Frame: Month 2 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaMinneapolisMinnesota55455
Ida-Arlaine Fonkoue, MD, PhD, MsCR
612-626-2520

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