Paid Clinical Trials in Minnesota

Minnesota has 2,375 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,375 clinical trials

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MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

for Lumbar Spinal Stenosis

2307 locations incl. Athens

Sponsor: Stryker Instruments

Sex: All·Age: 18+

Code: NCT03072927·Recruiting

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A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

for Locally Advanced Solid Tumors

Drug: Repotrectinib

49 locations incl. Duarte

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT03093116·Phase 1, Phase 2·Recruiting

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Thoracic Specimen Registry

for Thoracic Diseases

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04118660·Recruiting

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INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

for Glioblastoma

12 locations incl. Birmingham

Sponsor: Patrick Wen, MD

Sex: All·Age: 18+

Code: NCT02977780·Phase 2·Recruiting

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Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural

for Anesthesia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT05514431·Enrolling By Invitation

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

for Cryoglobulinemic Vasculitis (CV)

8 locations incl. Los Angeles

Sponsor: Peter Merkel

Sex: All·Age: 5+

Code: NCT03004326·Recruiting

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Biobank for Cholestatic Liver Diseases.

for Primary Sclerosing Cholangitis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT03445585·Recruiting

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Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

for Estrogen Receptor Negative

8 locations incl. Gilbert

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 30+

Code: NCT02945579·Recruiting

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Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

for Myeloid Malignancy

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT02958462·Recruiting

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PARTNER 3 Trial - Aortic Valve-in-Valve

for Aortic Stenosis

50 locations incl. Phoenix

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT03003299·Recruiting

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A Randomized Multicenter Study for Isolated Skin Vasculitis

for Primary Cutaneous Vasculitis

12 locations incl. Kansas City

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT02939573·Phase 2·Recruiting

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The Myelin Disorders Biorepository Project

for Leukodystrophy

23 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting

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International PPB/DICER1 Registry

for Pleuropulmonary Blastoma

1 location in Minneapolis

Sponsor: Children's Hospitals and Clinics of Minnesota

Sex: All·Age: 0 Minutes - 100·Accepts healthy volunteers

Code: NCT03382158·Recruiting

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Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis

for Myelofibrosis

1 location in Minneapolis

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 55+

Code: NCT02934477·Recruiting

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Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

for Previously Untreated Relapsed Refractory Acute Myeloid Leukemia

19 locations incl. Phoenix

Sponsor: Beat AML, LLC

Sex: All·Age: 18+

Code: NCT03013998·Phase 1, Phase 2·Recruiting

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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

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Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects

for Chronic Lymphocytic Leukemia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT06536452·Recruiting

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Late Onset Alzheimer's Disease

for Alzheimer Disease

12 locations incl. Washington D.C.

Sponsor: Columbia University

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT05010603·Recruiting

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Primary Tumor Research and Outcomes Network

for Spinal Column Tumor

9 locations incl. Los Angeles

Sponsor: AO Innovation Translation Center

Sex: All·Age: All ages

Code: NCT02790983·Recruiting

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His Bundle Pacing in Bradycardia and Heart Failure

for Bradycardia

1 location in Rochester

Sponsor: Yong-Mei Cha

Sex: All·Age: 18+

Code: NCT03008291·Recruiting

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The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

for Dupuytren Contracture

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03155854·Recruiting

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Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

for Parkinson's Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 89

Code: NCT05557864·Recruiting

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Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

12 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting

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Testicular Tissue Cryopreservation in Children

for Cancer

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Male·Age: 0 - 17

Code: NCT02872532·Recruiting

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Senescence in Chronic Kidney Disease

for Chronic Kidney Disease

2 locations incl. Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 40 - 80

Code: NCT02848131·Phase 2·Enrolling By Invitation

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

for Complex Congenital Heart Defect

25 locations incl. Little Rock

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT02744677·Recruiting

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Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

for Neuroblastoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 30

Code: NCT02605421·Phase 2·Recruiting

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Prospective Research Rare Kidney Stones (ProRKS)

for Hyperoxaluria

8 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT02780297·Recruiting

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Genetic Markers of Cardiovascular Disease in Epilepsy

for Epilepsy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 50

Code: NCT02824822·Recruiting

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

61 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting

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Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

for Langerhans Cell Histiocytosis

11 locations incl. Palo Alto

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 21

Code: NCT02670707·Phase 3·Recruiting

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A Clinical Registry of Orthobiologics Procedures

for Orthopedic Disorder

30 locations incl. Phoenix

Sponsor: Regenexx, LLC

Sex: All·Age: All ages

Code: NCT03011398·Enrolling By Invitation

The Oxford Risk Factors And Non-Invasive Imaging Study

for Cardiovascular Diseases

3 locations incl. Bethesda

Sponsor: University of Oxford

Sex: All·Age: 18 - 99

Code: NCT05169333·Recruiting

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Post-Exablate Pregnancy Outcomes Registry Study: Exablate Treatment of Symptomatic Uterine Fibroids

for Uterine Fibroid

3 locations incl. Los Angeles

Sponsor: InSightec

Sex: Female·Age: 18 - 50

Code: NCT05386615·Recruiting

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

24 locations incl. Birmingham

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting

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A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy

for Progressive Supranuclear Palsy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT02605785·Recruiting

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Effect of Treatment on Activity and Muscle Function in Pediatric Patients With Scoliosis

for Scoliosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 9 - 16

Code: NCT02610855·Enrolling By Invitation

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

for Primary T-cell Immunodeficiency Disorders

2 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 - 75·Accepts healthy volunteers

Code: NCT02579967·Phase 2·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

Apply to this trial