Clinical Trials at University of Minnesota

As of June 2026, 327 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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327 clinical trials at University of Minnesota

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Total Contact Soft Cast in Diabetic Foot Ulcers

for Diabetic Foot Ulcer

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT04210089·Recruiting

Apply to this trial

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

for Brain Tumor, Recurrent

54 locations incl. Phoenix

Sponsor: GT Medical Technologies, Inc.

Sex: All·Age: All ages

Code: NCT04427384·Recruiting

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Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

for Castration Resistant Metastatic Prostate Cancer

6 locations incl. San Diego

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male·Age: 18 - 90

Code: NCT04363164·Phase 2·Recruiting

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Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

13 locations incl. Tampa

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

for Age-related Cognitive Decline

6 locations incl. San Francisco

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 55 - 89

Code: NCT04171323·Recruiting

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Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

for Peripheral Artery Disease

7 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT04228978·Recruiting

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Bupropion for the Prevention of Postpartum Smoking Relapse

for Postpartum Smoking Relapse

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT04098874·Phase 4·Recruiting

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

32 locations incl. Birmingham

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting

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Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

for Open Midline Laparotomy

30 locations incl. Phoenix

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT03911700·Recruiting

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Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

for Congenital Disorders of Glycosylation

12 locations incl. San Diego

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: All ages

Code: NCT04199000·Recruiting

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Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

for C3 Glomerulopathy

Drug: Iptacopan

5 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT03955445·Phase 3·Recruiting

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Algorithms for Programming DBS Systems for ET

for Essential Tremor

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT03984643·Recruiting

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Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women

for Hypertension

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 35 - 70·Accepts healthy volunteers

Code: NCT04439370·Recruiting

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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

98 locations incl. Birmingham

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting

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Kidney Precision Medicine Project

for Acute Kidney Failure

13 locations incl. Tucson

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting

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Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

for Colonic Neoplasms

11 locations incl. Los Angeles

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT00843375·Recruiting

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Neuromodulation and Cognitive Training in Opioid Use Disorder

for Opioid-use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 60

Code: NCT03773523·Recruiting

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Post-contracture Release Radiation for Dupuytren's Disease

for Dupuytren's Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT04122313·Recruiting

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

18 locations incl. Gilbert

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

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Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

for Hodgkin Lymphoma

Drug: Ruxolitinib

6 locations incl. Chicago

Sponsor: Veronika Bachanova

Sex: All·Age: 18+

Code: NCT03681561·Phase 1, Phase 2·Recruiting

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North American Prodromal Synucleinopathy Consortium

for REM Sleep Behavior Disorder

9 locations incl. Sun City

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT03623672·Enrolling By Invitation

Advanced Materials Science in XLIF Study

for Degenerative Disc Disease

15 locations incl. Hartford

Sponsor: NuVasive

Sex: All·Age: 18 - 80

Code: NCT03649490·Enrolling By Invitation

Circuit-Based Deep Brain Stimulation for Parkinson's Disease; Udall Clinical Core

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT03021031·Enrolling By Invitation

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

for Malignant Peripheral Nerve Sheath Tumors

9 locations incl. Tampa

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages

Code: NCT03141021·Recruiting

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The Myelin Disorders Biorepository Project

for Leukodystrophy

23 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting

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Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

for Parkinson's Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 89

Code: NCT05557864·Recruiting

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Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

12 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

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Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

for Gaucher Disease Type I

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT02437396·Recruiting

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Imaging Biomarkers in ALS

for Amyotrophic Lateral Sclerosis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT02567136·Recruiting

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

75 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting

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Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

for Focal Segmental Glomerulosclerosis

12 locations incl. Loma Linda

Sponsor: Kaneka Medical America LLC

Sex: All·Age: Up to 21

Code: NCT02235857·Recruiting

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ALS/MND Natural History Study Data Repository

for ALS

14 locations incl. Loma Linda

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

44 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting

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Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

23 locations incl. Birmingham

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting

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Diagnostic and Therapeutic Applications in Microarrays in Organ Transplantation

for Validation Study of Molecular Diagnostic System

10 locations incl. Birmingham

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT01299168·Recruiting

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

16 locations incl. Birmingham

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting

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Natural History and Structural Functional Relationships in Fabry Renal Disease Treatment Outcomes(Changes)in Fabry Renal Disease Study

for Fabry Disease

2 locations incl. Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 1 - 75

Code: NCT01581424·Recruiting

Apply to this trial