Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT02437396
Status
Recruiting
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Conditions

  • Gaucher Disease Type I
  • Inflammation
  • Oxidative Stress

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Study Details

The objective of this study is to evaluate oxidative stress and/or inflammation in patients with Gaucher disease type I using a series of biomarkers and correlate with measurements of currently used diagnostic biomarkers.

Key Dates

Start date
Oct 31, 2015
Status verified
Mar 2026
Primary completion
Jun 28, 2026
Completion
Jun 28, 2026

Study Design

Enrollment
34 participants (estimated)

Arms

  • Arm: Treatment naive GD1
    Type 1 Gaucher disease subjects who are naive to any treatment
  • Arm: Treated GD1
    Type 1 Gaucher disease who are stable on therapy (on the specific ERT and/or SRT and specific dose for at least 2 years)
  • Arm: Healthy Volunteers (No longer recruiting)
    Age matched healthy controls. No new participants will be enrolled to this arm.

Primary Outcome Measure

Change in Plasma C5a Concentration [ Time Frame: 6 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaMinneapolisMinnesota55455
Reena Kartha, PhD
[email protected]
612-626-2436
Reena Kartha, PhD (PRINCIPAL_INVESTIGATOR)

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