A Study of BGB-11417 in Participants With Myeloid Malignanciesfor Acute Myeloid Leukemia5 locations incl. DuarteSponsor: BeiGeneSex: All·Age: 18+Code: NCT04771130·Phase 1, Phase 2·RecruitingApply to this trial
GORE® ENFORM Biomaterial Product Studyfor Hernia, Ventral9 locations incl. San DiegoSponsor: W.L.Gore & AssociatesSex: All·Age: 18+Code: NCT04718168·RecruitingApply to this trial
KRT-232 and TKI Study in Chronic Myeloid Leukemiafor Chronic Myeloid Leukemia5 locations incl. BirminghamSponsor: Kartos Therapeutics, Inc.Sex: All·Age: 18+Code: NCT04835584·Phase 1, Phase 2·RecruitingApply to this trial
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Riskfor Peripheral Arterial Disease19 locations incl. New HavenSponsor: Population Health Research InstituteSex: All·Age: 18+Code: NCT04774159·Phase 3·RecruitingApply to this trial
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinomafor Recurrent Head and Neck Squamous Cell Carcinoma178 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18 - 79Code: NCT04671667·Phase 2·RecruitingApply to this trial
Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndromefor Functional Gastrointestinal Disorders1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 10 - 18Code: NCT05212129·RecruitingApply to this trial
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trialfor Metastatic Clear Cell Renal Cell Carcinoma387 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT04510597·Phase 3·RecruitingApply to this trial
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcomafor Retroperitoneal Sarcoma109 locations incl. BirminghamSponsor: European Organisation for Research and Treatment of Cancer - EORTCSex: All·Age: 18+Code: NCT04031677·Phase 3·RecruitingApply to this trial
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trialfor Extensive Stage Lung Small Cell CarcinomaDrug: Atezolizumab416 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT04402788·Phase 2, Phase 3·RecruitingApply to this trial
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancerfor Advanced Lung Non-Squamous Non-Small Cell CarcinomaDrug: Bevacizumab604 locations incl. AnchorageSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT04181060·Phase 3·RecruitingApply to this trial
A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancersfor Advanced Solid TumorsDrug: Cemiplimab21 locations incl. Los AngelesSponsor: Regeneron PharmaceuticalsSex: All·Age: 18+Code: NCT04626635·Phase 1, Phase 2·RecruitingApply to this trial
Parkinson's Foundation PD GENEration Genetic Registryfor Parkinson's Disease54 locations incl. BirminghamSponsor: Parkinson's FoundationSex: All·Age: 18+Code: NCT04994015·RecruitingApply to this trial
Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastomafor Neuroblastoma25 locations incl. BirminghamSponsor: Giselle ShollerSex: All·Age: Up to 31Code: NCT04301843·Phase 2·RecruitingApply to this trial
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancerfor Buccal Mucosa Squamous Cell Carcinoma105 locations incl. BirminghamSponsor: NRG OncologySex: All·Age: 18+Code: NCT04333537·Phase 2, Phase 3·RecruitingApply to this trial
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancerfor Ovarian Carcinoma539 locations incl. BirminghamSponsor: NRG OncologySex: Female·Age: 35 - 50Code: NCT04251052·RecruitingApply to this trial
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adultsfor Cognitive Impairment, Mild102 locations incl. BirminghamSponsor: Duke UniversitySex: All·Age: 75+·Accepts healthy volunteersCode: NCT04262206·Phase 4·RecruitingApply to this trial
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)for Viral Infection7 locations incl. San FranciscoSponsor: New York Medical CollegeSex: All·Age: 1 Month - 79Code: NCT04197596·Phase 1, Phase 2·RecruitingApply to this trial
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])for Lung Non-Small Cell Carcinoma1150 locations incl. AnchorageSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT04267848·Phase 3·RecruitingApply to this trial
HEALEY ALS Platform Trial - Master Protocolfor Amyotrophic Lateral Sclerosis81 locations incl. PhoenixSponsor: Merit E. Cudkowicz, MDSex: All·Age: 18+Code: NCT04297683·Phase 2, Phase 3·RecruitingApply to this trial
Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trialfor Prostate AdenocarcinomaDrug: Apalutamide345 locations incl. PhoenixSponsor: NRG OncologySex: Male·Age: 18+Code: NCT04134260·Phase 3·RecruitingApply to this trial
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effectsfor Malignancy626 locations incl. AnchorageSponsor: Alliance for Clinical Trials in OncologySex: All·Age: All agesCode: NCT04242095·RecruitingApply to this trial
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)for Coronavirus Infection (COVID-19)49 locations incl. PhoenixSponsor: Duke UniversitySex: All·Age: 0 - 20·Accepts healthy volunteersCode: NCT04278404·RecruitingApply to this trial
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancerfor Neoplasms30 locations incl. BirminghamSponsor: Eli Lilly and CompanySex: All·Age: 1 - 39Code: NCT05999994·Phase 2·RecruitingApply to this trial
LinguaFlex Tongue Retractor (LTR) for the Treatment of OSA and Snoring in Adultsfor Obstructive Sleep Apnea3 locations incl. BrightonSponsor: Linguaflex, Inc.Sex: All·Age: 18+Code: NCT04129229·Enrolling By Invitation
Transcranial Alternating Current Stimulation (tACS) in Aphasiafor Aphasia1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18 - 85·Accepts healthy volunteersCode: NCT04375722·RecruitingApply to this trial
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Blockfor Heart Block Complete12 locations incl. PhoenixSponsor: The Hospital for Sick ChildrenSex: Female·Age: 16 - 50Code: NCT04559425·RecruitingApply to this trial
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)for Relapsing Multiple Sclerosis22 locations incl. Palo AltoSponsor: National Institute of Allergy and Infectious Diseases (NIAID)Sex: All·Age: 18 - 55Code: NCT04047628·Phase 3·RecruitingApply to this trial
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanomafor Cutaneous Melanoma, Stage II130 locations incl. MobileSponsor: Melanoma and Skin Cancer Trials LimitedSex: All·Age: 18+Code: NCT03860883·RecruitingApply to this trial
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trialfor Tricuspid Regurgitation73 locations incl. PhoenixSponsor: Edwards LifesciencesSex: All·Age: 18+Code: NCT04097145·RecruitingApply to this trial
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Studyfor Lower Respiratory Tract Infection49 locations incl. DuarteSponsor: Ansun Biopharma, Inc.Sex: All·Age: All agesCode: NCT03808922·Phase 3·RecruitingApply to this trial
Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemiafor B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative275 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT03739814·Phase 2·RecruitingApply to this trial
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgeryfor Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7140 locations incl. TucsonSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT03493425·Phase 2·RecruitingApply to this trial
Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)for Non-Hodgkin Lymphoma18 locations incl. GilbertSponsor: Imugene LimitedSex: All·Age: 18+Code: NCT03666000·Phase 1·RecruitingApply to this trial
Oxytocin and Fetal Heart Rate Changesfor Fetal Bradycardia Complicating Labor and Delivery2 locations incl. Iowa CitySponsor: Unyime ItukSex: Female·Age: 18 - 55·Accepts healthy volunteersCode: NCT03232918·Phase 4·RecruitingApply to this trial
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancerfor Previously Treated Non-Small Cell Lung Cancer1229 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT03851445·Phase 2, Phase 3·RecruitingApply to this trial
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Studyfor Oncology3 locations incl. PittsburghSponsor: UMC UtrechtSex: All·Age: 18+Code: NCT04075305·RecruitingApply to this trial
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastasesfor Brain Metastases73 locations incl. TucsonSponsor: Canadian Cancer Trials GroupSex: All·Age: 18+Code: NCT03550391·Phase 3·RecruitingApply to this trial
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infectionsfor Pulmonary Invasive Fungal Infections32 locations incl. Little RockSponsor: Arkansas Children's Hospital Research InstituteSex: All·Age: 120 Days - 21Code: NCT03827694·RecruitingApply to this trial
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Kneefor Chondral Defect12 locations incl. Palo AltoSponsor: Vericel CorporationSex: All·Age: 10 - 17Code: NCT03588975·Phase 3·RecruitingApply to this trial
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancerfor Breast Cancer451 locations incl. FairbanksSponsor: Canadian Cancer Trials GroupSex: Female·Age: 35+Code: NCT03488693·Phase 3·RecruitingApply to this trial