Transcranial Alternating Current Stimulation (tACS) in Aphasia
Part of paid clinical trials in Milwaukee, Wisconsin.
- Sponsor
- Medical College of Wisconsin
- Study ID
- NCT04375722
- Status
- Recruiting
Conditions
- Aphasia
- Stroke
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 85 Years
- Healthy Volunteers
- Accepted
Interventions
- tACS — DEVICEActive or Sham tACS will be applied.
Study Details
This study will assess the effects of transcranial alternating current stimulation (tACS) on language recovery after stroke as well as healthy language functions.
Key Dates
- Start date
- Jan 4, 2020
- Status verified
- May 2025
- Primary completion
- Jan 31, 2030
- Completion
- Dec 31, 2030
Study Design
- Enrollment
- 50 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: tACS 10 Hz low frequencyAll participants in a within-subject design will receive high-Definition-tACS, delivered via a battery operated alternating current stimulator (Soterix) using two 3x1 center-surround montages. Targets of stimulation will be localized based on the 10-10 International EEG system with center electrodes placed at a frontal and a temporoparietal site. The current is turned on and increased in a ramplike fashion over approximately 30 seconds. Participants will undergo tACS with frequencies ranging from 4-40Hz for 20-minutes with 2 milliampere (mA) peak-to-peak intensity. For sham stimulation, tACS is turned off after the first 30 seconds.
Primary Outcome Measure
tACS changes in language performance verbal STM tasks [ Time Frame: Changes monitored over pre, during and immediately after 20 minutes of tACS ]
Central Contacts
- Sidney Schoenrock, MA414-955-7579
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 |
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