Paid Clinical Trials in Michigan

Michigan has 2,328 paid clinical trials enrolling now across cities including Ann Arbor, Detroit and Grand Rapids. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Michigan include University of Michigan Health and Henry Ford Health, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,328 clinical trials

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Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

116 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04743141·Phase 3·Recruiting

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for Low-grade Glioma

14 locations incl. San Francisco

Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All·Age: 6 Months - 25

Code: NCT04775485·Phase 2·Recruiting

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A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

for Ovarian Neoplasms

Drug: Niraparib

13 locations incl. Tucson

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT04641247·Phase 2·Recruiting

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Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for Propionic Acidemia

15 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: All ages

Code: NCT04159103·Phase 1, Phase 2·Recruiting

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Longitudinal Oral Microbiome Sampling for BE

for Barrett Esophagus

2 locations incl. Ann Arbor

Sponsor: Columbia University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05133102·Recruiting

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Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

for Locally Advanced or Metastatic Non-Small Cell Lung Cancer

13 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT04686305·Phase 1·Recruiting

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Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

for Advanced Solid Tumor Cancer

Drug: ABBV-CLS-484

15 locations incl. Tucson

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18+

Code: NCT04777994·Phase 1·Recruiting

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

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Fenofibrate for Prevention of DR Worsening

for Diabetic Retinopathy

66 locations incl. Glendale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18 - 80

Code: NCT04661358·Phase 3·Recruiting

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

31 locations incl. Phoenix

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting

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Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

for Rotator Cuff Tears

10 locations incl. Iowa City

Sponsor: University of Michigan

Sex: All·Age: 40 - 85

Code: NCT04831164·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

620 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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KIDney Injury in Times of COVID-19 (KIDCOV)

for SARS-CoV Infection

3 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04705766·Recruiting

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Exercise Effects on Adipose Tissue Structure and Function

for Obesity

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 40

Code: NCT04812314·Recruiting

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Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

for Plasma Cell Myeloma

642 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT04566328·Phase 3·Recruiting

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Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old

for Migraine Disorders

15 locations incl. Birmingham

Sponsor: Upsher-Smith Laboratories

Sex: All·Age: 6 - 11

Code: NCT04748601·Phase 4·Recruiting

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

163 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting

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REVEAL Biomarkers of Engraftment After Alternative Donor HSCT

for Primary Graft Failure

4 locations incl. Atlanta

Sponsor: University of Oklahoma

Sex: All·Age: 4 - 80

Code: NCT03541889·Phase 1·Recruiting

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ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)

for Acute Respiratory Distress Syndrome

76 locations incl. Birmingham

Sponsor: University of Michigan

Sex: All·Age: 14 Days - 20

Code: NCT05388708·Recruiting

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A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

for Hematological Malignancies

Drug: Talquetamab

14 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04634552·Phase 2·Recruiting

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Assessment of the Utility of the Pantheris Small Vessel (SV) System

for Peripheral Arterial Disease

2 locations incl. Grand Rapids

Sponsor: Avinger, Inc.

Sex: All·Age: 18+

Code: NCT04793581·Recruiting

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Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)

for Alzheimer Dementia

5 locations incl. Atlanta

Sponsor: Brent Forester

Sex: All·Age: 40+

Code: NCT03926520·Recruiting

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Isatuximab in Combination With Novel Agents in RRMM - Master Protocol

for Plasma Cell Myeloma Refractory

5 locations incl. Atlanta

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT04643002·Phase 1, Phase 2·Recruiting

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Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for Retroperitoneal Sarcoma

109 locations incl. Birmingham

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All·Age: 18+

Code: NCT04031677·Phase 3·Recruiting

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The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

10 locations incl. San Diego

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting

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Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)

for Radiotracer

1 location in Ann Arbor

Sponsor: Benjamin Viglianti

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04532489·EARLY_Phase 1·Recruiting

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Randomized Study in Children and Adolescents With Migraine: Acute Treatment

for Pediatric Migraine

169 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04649242·Phase 3·Recruiting

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Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

for Locally Advanced Pancreatic Adenocarcinoma

Drug: Peposertib

44 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04172532·Phase 1, Phase 2·Recruiting

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Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

for Sleep Disordered Breathing

1 location in Detroit

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04118387·Phase 4·Recruiting

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Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

416 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04402788·Phase 2, Phase 3·Recruiting

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

331 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting

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Groningen International Study on Sentinel Nodes in Vulvar Cancer-III

for Vulvar Cancer

21 locations incl. Orange

Sponsor: University Medical Center Groningen

Sex: Female·Age: 18+

Code: NCT05076942·Phase 2·Recruiting

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for Advanced Lung Non-Squamous Non-Small Cell Carcinoma

Drug: Bevacizumab

603 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04181060·Phase 3·Recruiting

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Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

for Carpal Tunnel Syndrome

1 location in Detroit

Sponsor: Henry Ford Health System

Sex: All·Age: 18+

Code: NCT04737239·Recruiting

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Secukinumab Open Label Roll-over Extension Protocol

for Autoimmunity, Inflammation

Drug: Secukinumab

28 locations incl. Fullerton

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 6 - 100

Code: NCT04638647·Phase 4·Recruiting

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A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

for Advanced Solid Tumors

Drug: Cemiplimab

21 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04626635·Phase 1, Phase 2·Recruiting

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

55 locations incl. Huntsville

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting

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Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

for Heart Failure With Preserved Ejection Fraction (HFpEF

20 locations incl. Birmingham

Sponsor: Axon Therapies, Inc.

Sex: All·Age: 40+

Code: NCT04592445·Recruiting

Apply to this trial