Dementia care Clinical Trials in Matthews, NC
As of June 2026, 5 paid clinical trials are recruiting for Dementia care in Matthews, North Carolina. Dementia care research evaluates disease-modifying anti-amyloid antibodies, cognitive-enhancing drugs, and supportive care interventions for Alzheimer's disease and related cognitive disorders. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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5 clinical trials for Dementia care
·Clear filters·↓ Download CSVA Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
About research studies in Matthews
Matthews has approximately 24 recruiting research studies across a wide range of therapeutic areas. North Carolina hosts Duke University Medical Center, UNC Health, and Wake Forest Baptist Health, with strong programs in oncology, cardiovascular disease, and translational research anchored by Research Triangle Park.
Top Research Study Locations in Matthews
Researchers run research studies in Matthews, NC at 11 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Novant Health Cancer Institute - Matthews | Anatomic Stage II Breast Cancer AJCC v8, Advanced Lung Non-Squamous Non-Small Cell Carcinoma, Anaplastic Large Cell Lymphoma, ALK-Negative | 10 |
| Levine Cancer Institute - Union West | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 8 |
| Matthews Radiation Oncology Center | Anaplastic Large Cell Lymphoma, ALK-Negative, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 7 |
| AMC Research, LLC - Flourish - PPDS | Alzheimer Disease, Psychosis Associated With Alzheimer's Disease | 2 |
| AMC Research, LLC | Alzheimer's Disease, Early Alzheimer's Disease | 2 |
| Alzheimer's Memory Center - AMC Research | AD, Alzheimer Disease, Cognitive Impairment | 1 |
| Flourish Research | Alzheimer's Disease, Amyloid Plaque, Beta-Amyloid | 1 |
| GSK Investigational Site | Alzheimer's Disease | 1 |
| Levine Cancer Institute | Metastatic Breast Cancer | 1 |
| Metrolina Eye Associates | Cataract | 1 |
| Novant Health Matthews Med Ctr | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Matthews (2026)
Recruiting trials in Matthews grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (14 active studies)
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
- Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response · Phase 3 · Canadian Cancer Trials Group
Neurology & pain (2 active studies)
- A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4) · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015) · Cognito Therapeutics, Inc.
Eye & vision (1 active study)
- Unity VCS: A Comparison Study Evaluating Corneal Clarity and Thickness · Metrolina Eye Associates, PLLC
Common conditions studied in Matthews
- Alzheimer's Disease (3 active studies). Recruiting Alzheimer's Disease studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Alzheimer Disease (2 active studies). Alzheimer's research investigates anti-amyloid antibodies, tau-targeted therapies, and lifestyle interventions aimed at slowing cognitive decline.
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- AD (1 active study). Recruiting AD studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Lung Non-Squamous Non-Small Cell Carcinoma (1 active study). Recruiting Advanced Lung Non-Squamous Non-Small Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Amyloid Plaque (1 active study). Recruiting Amyloid Plaque studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Matthews
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- AC Immune SA
Local regulations and guidelines
Clinical trials in North Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. North Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Matthews. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Matthews
Hipa.ai aggregates every recruiting study in Matthews from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Matthews?
There are approximately 24 recruiting clinical trials in Matthews, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Matthews pay participants?
Most recruiting trials in Matthews compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Matthews?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Matthews?
The most common conditions under active study in Matthews include Alzheimer's Disease (3), Alzheimer Disease (2), Anatomic Stage II Breast Cancer AJCC v8 (2), AD (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Matthews?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Matthews on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Matthews?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Matthews?
Recruiting research sites in Matthews include Novant Health Cancer Institute - Matthews, Levine Cancer Institute - Union West, Matthews Radiation Oncology Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Matthews right now?
The largest active categories in Matthews are Cancer & tumors (14), Neurology & pain (2), Eye & vision (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.