Paid Clinical Trials in Hillsborough, NC
As of June 2026, 19 paid clinical trials are recruiting in Hillsborough, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Hillsborough offers studies at sites including University of North Carolina-Hillsborough Campus for conditions such as Becker Muscular Dystrophy, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Hillsborough
Trials by drug in Hillsborough
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19 clinical trials
↓ Download CSVEfficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
Shield Post-Approval Study Protocol
Oral Ketorolac for IUD Pain Reduction
Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
CureDuchenne Link®: A Resource for Research
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
About research studies in Hillsborough
Hillsborough has approximately 19 recruiting research studies across a wide range of therapeutic areas. North Carolina hosts Duke University Medical Center, UNC Health, and Wake Forest Baptist Health, with strong programs in oncology, cardiovascular disease, and translational research anchored by Research Triangle Park.
Top Research Study Locations in Hillsborough
Researchers run research studies in Hillsborough, NC at 13 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of North Carolina-Hillsborough Campus | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 6 |
| Rare Disease Research, LLC | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, DM1, DMD | 2 |
| Rare Disease Research | Angelman Syndrome | 1 |
| Rare Disease Research Center | Becker Muscular Dystrophy, Duchenne Muscular Dystrophy | 1 |
| Rare Disease Research NC, LLC | Spinal Muscular Atrophy (SMA) | 1 |
| Rare Disease Research, LLC NC | Becker Muscular Dystrophy | 1 |
| UNC Hospitals - Hillsborough Campus | Lumbar Spinal Stenosis | 1 |
| UNC Hospitals Hillsborough Campus | Pneumonia | 1 |
| University Of North Carolina Health Care - Hillsborough Campus | Multiple Myeloma | 1 |
| University of North Carolina - Hillsborough Campus | IUD Insertion Pain | 1 |
| University of North Carolina Hospitals - Hillsborough Campus | Cutaneous Melanoma, Stage II | 1 |
| University of North Carolina Hospitals at Hillsborough | Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma | 1 |
| University of North Carolina at Chapel Hill | Colo-rectal Cancer | 1 |
Active & Upcoming Studies in Hillsborough (2026)
Recruiting trials in Hillsborough grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (8 active studies)
- Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma · Phase 1 · AbbVie
- Shield Post-Approval Study Protocol · Guardant Health, Inc.
Neurology & pain (1 active study)
- Oral Ketorolac for IUD Pain Reduction · Phase 2 · University of North Carolina, Chapel Hill
Pediatric (1 active study)
Common conditions studied in Hillsborough
- Becker Muscular Dystrophy (2 active studies). Recruiting Becker Muscular Dystrophy studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Esophageal Adenocarcinoma (1 active study). Recruiting Advanced Esophageal Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Gastric Adenocarcinoma (1 active study). Recruiting Advanced Gastric Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Gastroesophageal Junction Adenocarcinoma (1 active study). Recruiting Advanced Gastroesophageal Junction Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Anatomic Stage I Breast Cancer AJCC v8 (1 active study). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (1 active study). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Hillsborough
- Dyne Therapeutics
- Pfizer
- AbbVie
- Alliance for Clinical Trials in Oncology
- CureDuchenne
Local regulations and guidelines
Clinical trials in North Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. North Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Hillsborough. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Hillsborough
Hipa.ai aggregates every recruiting study in Hillsborough from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Hillsborough?
There are approximately 19 recruiting clinical trials in Hillsborough, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Hillsborough pay participants?
Most recruiting trials in Hillsborough compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Hillsborough?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Hillsborough?
The most common conditions under active study in Hillsborough include Becker Muscular Dystrophy (2), Advanced Esophageal Adenocarcinoma (1), Advanced Gastric Adenocarcinoma (1), Advanced Gastroesophageal Junction Adenocarcinoma (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Hillsborough?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Hillsborough on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Hillsborough?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Hillsborough?
Recruiting research sites in Hillsborough include University of North Carolina-Hillsborough Campus, Rare Disease Research, LLC, Rare Disease Research, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Hillsborough right now?
The largest active categories in Hillsborough are Cancer & tumors (8), Neurology & pain (1), Pediatric (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.