Paid Clinical Trials in Massachusetts

Massachusetts has 3,586 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,586 clinical trials

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Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

for Spinal Muscular Atrophy Type 3

3 locations incl. Palo Alto

Sponsor: Columbia University

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT06839469·Recruiting

Apply to this trial

TENS Unit for Analgesia During IUD Insertion

for IUD

1 location in Boston

Sponsor: Tufts Medical Center

Sex: Female·Age: 12 - 50·Accepts healthy volunteers

Code: NCT06240260·Recruiting

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A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

33 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 12+

Code: NCT06338995·Phase 3·Recruiting

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PostureCheck: A Vision-based Compensatory-posture-detection Tool for Robot-assisted Upper-limb Therapy

for Stroke

1 location in Charlestown

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 80

Code: NCT04851886·Recruiting

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Study of REM-422 in Patients With AML or Higher Risk MDS

for Myelodysplastic Syndromes

5 locations incl. Duarte

Sponsor: Remix Therapeutics

Sex: All·Age: 18+

Code: NCT06297941·Phase 1·Recruiting

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

134 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting

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Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

for Binge-Eating Disorder

Drug: Solriamfetol

45 locations incl. Encino

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 55

Code: NCT06413433·Phase 3·Recruiting

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A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

for Atrial Fibrillation

35 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06335082·Enrolling By Invitation

Protocol CAUSE-03 / CHEETAH

for Asthma

8 locations incl. Aurora

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 6 - 17·Accepts healthy volunteers

Code: NCT06136091·Recruiting

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Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

4 locations incl. Scarborough

Sponsor: Inhye Ahn

Sex: All·Age: 18+

Code: NCT06333262·Phase 2·Recruiting

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A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

for Squamous Cell Carcinoma of Head and Neck

Drug: Amivantamab

15 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06385080·Phase 1, Phase 2·Recruiting

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Evaluation of a Twenty-session Cognitive-behavioral Therapy With Anorexia Nervosa (CBT-20-AN) Among Adults (18+)

for Anorexia Nervosa

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06597305·Enrolling By Invitation

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

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A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

for Cancer

4 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 25 - 39

Code: NCT06172907·Recruiting

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A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

38 locations incl. Little Rock

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06319820·Phase 3·Recruiting

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CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State

for Perioperative/Postoperative Complications

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06133842·Recruiting

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Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

for Advanced Solid Tumor

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06302621·Phase 1·Recruiting

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

22 locations incl. Englewood

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting

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MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

for In-Stent Restenosis

28 locations incl. Birmingham

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 110

Code: NCT05908331·Recruiting

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Pivotal Trial of the Boomerang Catheter for pDVA

for Chronic Limb-Threatening Ischemia

19 locations incl. Sylmar

Sponsor: Aveera Medical, Inc.

Sex: All·Age: 18+

Code: NCT06311773·Enrolling By Invitation

Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

34 locations incl. Birmingham

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

61 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting

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PRESSURE CHECK: Find Your Path to Better Health

for Blood Pressure

4 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06122246·Recruiting

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A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for Breast Neoplasms

46 locations incl. Chandler

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312176·Phase 3·Recruiting

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Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

for Arthritis

7 locations incl. Carmel

Sponsor: Aptis Medical

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05796908·Recruiting

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

166 locations incl. Alexander City

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting

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Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking

for Epilepsy

1 location in Boston

Sponsor: Empatica, Inc.

Sex: All·Age: 6+

Code: NCT06275685·Recruiting

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Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for Non-Small Cell Lung Cancer

Drug: Rilvegostomig

63 locations incl. Anchorage

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06357533·Phase 3·Recruiting

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Mindfulness-Based fMRI Neurofeedback for Depression

for Depression in Adolescence

2 locations incl. Boston

Sponsor: Columbia University

Sex: All·Age: 13 - 18

Code: NCT05617495·Recruiting

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Language During Inhalational Induction

for Emergence Delirium

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 5 - 10

Code: NCT06324955·Recruiting

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Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for Hematologic Malignancy

5 locations incl. Duarte

Sponsor: Tr1X, Inc.

Sex: All·Age: 18+

Code: NCT06462365·Phase 1·Recruiting

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AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

for Aortic Aneurysm, Abdominal

39 locations incl. Birmingham

Sponsor: Shape Memory Medical, Inc.

Sex: All·Age: 18+

Code: NCT06029660·Recruiting

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Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

for Acne

79 locations incl. Scottsdale

Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All·Age: 18 - 45

Code: NCT06316297·Phase 1, Phase 2·Recruiting

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Patient-Reported Outcomes and Quality of Life in Adult and Pediatric Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma (NLPHL)

for Nodular Lymphocyte-Predominant Hodgkin Lymphoma

7 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 8+

Code: NCT06098430·Recruiting

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Asthma Link Effectiveness Trial

for Childhood Asthma

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 5 - 14

Code: NCT06388460·Recruiting

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Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation

for Delirium

2 locations incl. Boston

Sponsor: Penn State University

Sex: All·Age: 70+

Code: NCT05915377·Recruiting

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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

59 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06329401·Phase 2·Recruiting

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A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care

for Insomnia

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT05759065·Recruiting

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Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia

for Schizophrenia

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18 - 65

Code: NCT06174116·Phase 4·Recruiting

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Biomarkers Research in Anxiety for Validation and Efficacy

for Autism

1 location in Brookline

Sponsor: Boston Children's Hospital

Sex: All·Age: 3 - 6

Code: NCT06221176·Recruiting

Apply to this trial