Patient-Reported Outcomes and Quality of Life in Adult and Pediatric Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma (NLPHL)
Part of paid clinical trials in Palo Alto, California.
- Sponsor
- St. Jude Children's Research Hospital
- Study ID
- NCT06098430
- Status
- Recruiting
Conditions
- Nodular Lymphocyte-Predominant Hodgkin Lymphoma
Eligibility Criteria
- Sex
- ALL
- Age
- 8 Years - N/A
- Healthy Volunteers
- Not accepted
Study Details
There is a pressing need to measure patient-reported symptoms in patients of all ages diagnosed with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). This study aims to measure longitudinal symptom burden and treatment tolerability utilizing validated patient-reported outcomes (PROs) instruments. Primary Objective: * To develop the data collection infrastructure required to prospectively collect longitudinal electronic patient-reported outcomes (PROs) survey instruments in adult and pediatric patients diagnosed with NLPHL. Secondary Objective: * To examine differences in baseline and longitudinal changes in PROs based on disease characteristics, disease status, and treatment strategies among adult and pediatric patients diagnosed with NLPHL.
Key Dates
- Start date
- Apr 4, 2024
- Status verified
- May 2026
- Primary completion
- Dec 31, 2026
- Completion
- Jan 31, 2028
Study Design
- Enrollment
- 100 participants (estimated)
Primary Outcome Measure
Estimates of response rates [ Time Frame: At baseline, 3, 6, 9, and 12 months ]
Central Contacts
- Valerie Crabtree, PhD888-226-4343
- Jessi Rogers Blake, BSN,RN,CCRP901-595-4108
Locations (7)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Stanford University Medical Center | Palo Alto | California | 94304 | Michael Binkley, MD (PRINCIPAL_INVESTIGATOR) |
| University of Colorado Hospital | Aurora | Colorado | 80045 | Ajay Major, MD, MBA (PRINCIPAL_INVESTIGATOR) |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Angela Feraco, MD (PRINCIPAL_INVESTIGATOR) |
| Hackensack University Medical Center | Hackensack | New Jersey | 08837 | Burton Appel, MD, MBA (PRINCIPAL_INVESTIGATOR) |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Christopher Forlenza, MD (PRINCIPAL_INVESTIGATOR) |
| University of Rochester Medical Center | Rochester | New York | 14642 | Jamie Flerlage, MD, MS (PRINCIPAL_INVESTIGATOR) |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | Valerie Crabtree, PhD (PRINCIPAL_INVESTIGATOR) Anna Jones, PhD (PRINCIPAL_INVESTIGATOR) Matthew Rees, MD (PRINCIPAL_INVESTIGATOR) |