Paid Clinical Trials in Massachusetts

Massachusetts has 3,584 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,584 clinical trials

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

34 locations incl. Laguna Hills

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting

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Burning Mouth Syndrome: Symptoms and Management

for Burning Mouth Syndrome

1 location in Amherst

Sponsor: University of Massachusetts, Amherst

Sex: All·Age: 18+

Code: NCT07016555·EARLY_Phase 1·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting

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REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

for Angelman Syndrome

15 locations incl. Los Angeles

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 50

Code: NCT06914609·Phase 3·Recruiting

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Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

10 locations incl. Newport Beach

Sponsor: Ensem Therapeutics

Sex: All·Age: 18+

Code: NCT06993844·Phase 1, Phase 2·Recruiting

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A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

for Facioscapulohumeral Muscular Dystrophy

14 locations incl. Orange

Sponsor: Avidity Biosciences, Inc.

Sex: All·Age: 16 - 70

Code: NCT07038200·Phase 3·Recruiting

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Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

for Agitation

53 locations incl. Homewood

Sponsor: Celgene

Sex: All·Age: 55 - 90

Code: NCT06808984·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for Autosomal Dominant Polycystic Kidney Disease

35 locations incl. Garden Grove

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18 - 55

Code: NCT06902558·Phase 2·Recruiting

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Low Oxygen Therapy to Enhance Walking Recovery After SCI.

for Spinal Cord Injuries

2 locations incl. Jacksonville

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 80

Code: NCT06521723·Recruiting

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Wearable Evaluation of Ambulatory Readings for Blood Pressure

for Normal Blood Pressure

1 location in Boston

Sponsor: Stephen Juraschek

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06610448·Recruiting

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The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium

for Delirium, Postoperative

3 locations incl. Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 60+

Code: NCT06721819·Phase 3·Recruiting

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HLA Demographics Study in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type I

5 locations incl. San Francisco

Sponsor: GentiBio, Inc

Sex: All·Age: 18 - 55

Code: NCT06860516·Recruiting

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

for Multiple Sclerosis Spasticity

15 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18 - 70

Code: NCT06782490·Phase 2·Recruiting

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Outpatient Epcoritamab as 2L in NTE R/R DLBCL

for Relapsed Large B-cell Lymphoma

Drug: Epcoritamab

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06811272·Phase 2·Recruiting

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Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

for Lymphoma

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06923397·Recruiting

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Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

for Trauma Injury

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT06812247·Recruiting

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

50 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting

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A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

for Dravet Syndrome

Drug: zorevunersen

31 locations incl. Phoenix

Sponsor: Stoke Therapeutics, Inc

Sex: All·Age: 2 - 17

Code: NCT06872125·Phase 3·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

for Solid Tumor Cancer

18 locations incl. Gilbert

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07038343·Phase 1, Phase 2·Recruiting

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The Role of Vitamin K on Knee Osteoarthritis Outcomes

for Osteo Arthritis Knee

1 location in Boston

Sponsor: Boston University

Sex: All·Age: 60+

Code: NCT06385275·Phase 1, Phase 2·Recruiting

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

32 locations incl. Mobile

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting

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Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for Non-Muscle Invasive Bladder Urothelial Carcinoma

131 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06770582·Phase 2·Recruiting

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XL092 and Cemiplimab in BRAF WT Thyroid Cancer

for Anaplastic Thyroid Cancer

Drug: Cemiplimab

2 locations incl. Boston

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06902376·Phase 1·Recruiting

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A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

for Crohn's Disease

20 locations incl. Tucson

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06958536·Phase 2·Recruiting

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Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms

for Technical Sucess

1 location in Springfield

Sponsor: Baystate Medical Center

Sex: All·Age: 18+

Code: NCT07019454·Recruiting

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Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

for Crohn Disease

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07033208·Recruiting

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Assessing Optimal XRB Initiation Points in Jail

for Opioid Use Disorder

4 locations incl. Boston

Sponsor: NYU Langone Health

Sex: Male·Age: All ages

Code: NCT06051890·Phase 4·Recruiting

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Semaglutide for Helping Opioid Recovery

for Opioid Use Disorder

Drug: Semaglutide

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06639464·Phase 2·Recruiting

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Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)

for Stenosis of Trachea

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: All ages

Code: NCT06761170·Phase 2·Recruiting

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TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

for Cystic Fibrosis (CF)

13 locations incl. Orange

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18 Months - 11

Code: NCT07048574·Recruiting

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Preventing T2DM After GDM With Immediate Postpartum Screening

for Gestational Diabetes

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06457139·Recruiting

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Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy

for Postoperative Pain

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06483659·Phase 2·Recruiting

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A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

for Venous Leg Ulcer (VLU)

14 locations incl. Fresno

Sponsor: MediWound Ltd

Sex: All·Age: 18+

Code: NCT06568627·Phase 3·Recruiting

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Assessing Tenapanor as a Treatment of CF-related Constipation.

for Cystic Fibrosis

Drug: Tenapanor

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 75

Code: NCT06810167·Phase 3·Recruiting

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Registry and Natural History of Epilepsy-Dyskinesia Syndromes

for Epilepsy-Dyskinesia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 30

Code: NCT06967727·Recruiting

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A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome

for Memory Replay

1 location in Chestnut Hill

Sponsor: Boston College

Sex: All·Age: 15 - 35

Code: NCT07008989·Recruiting

Apply to this trial