Clinical Trials at University of Kentucky

As of June 2026, 138 paid clinical trials are recruiting at University of Kentucky, located at University of Kentucky Research Foundation, Kinkead Hall, 201 Kinkead Hall, Lexington, KY 40508, phone (859) 257-8311 in Lexington, Kentucky. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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138 clinical trials at University of Kentucky

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Opioid Education Ventral Hernia Repair

for Ventral Hernia Repair

1 location in Lexington

Sponsor: Tori Dotson

Sex: All·Age: 18 - 85

Code: NCT07639281·Enrolling By Invitation

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

60 locations incl. Anchorage

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT06072482·Phase 4·Recruiting

Apply to this trial

Precision Medicine Approach for Osteoporosis - Follow Up Study

for Osteoporosis

1 location in Lexington

Sponsor: Paul F Netzel

Sex: Female·Age: 45+

Code: NCT06264609·Phase 4·Enrolling By Invitation

Comprehensive Connected Cancer Care (C4): Intervention Evaluation

for Cancer

1 location in Lexington

Sponsor: Timothy Mullett

Sex: All·Age: 18+

Code: NCT06326567·Recruiting

Apply to this trial

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

for Myasthenia Gravis

11 locations incl. Aurora

Sponsor: Ad scientiam

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05564936·Recruiting

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A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

for Diffuse Large B-cell Lymphoma (DLBCL)

Drug: Odronextamab

20 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06091865·Phase 3·Recruiting

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Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment

for Lung Cancer

1 location in Lexington

Sponsor: Laurie McLouth

Sex: All·Age: 18+

Code: NCT06047301·Recruiting

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Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

70 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting

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Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for Neuroendocrine Tumors Unresectable

19 locations incl. Jacksonville

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05636618·Phase 1, Phase 2·Recruiting

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Creating VIP Corps to Reduce Maternal Deaths

for Maternal Morbidity and Mortality

1 location in Lexington

Sponsor: Ann Coker

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT06089109·Recruiting

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CSTOP Now! Child Sex Trafficking Stops With You

for Child Sex Trafficking

1 location in Lexington

Sponsor: Ann Coker

Sex: All·Age: 21 - 65

Code: NCT05722769·Recruiting

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

37 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting

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Pembro With Radiation With or Without Olaparib

for Prostate Cancer

2 locations incl. Lexington

Sponsor: Zin W Myint

Sex: Male·Age: 18+

Code: NCT05568550·Phase 2·Recruiting

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Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

for Recurrent Melanoma (Skin)

Drug: Nivolumab

13 locations incl. Orange

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05655312·Phase 1, Phase 2·Recruiting

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Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

14 locations incl. Gainesville

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

26 locations incl. Tucson

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting

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REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19

for COVID-19

5 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05218083·Recruiting

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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

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Muscle Recovery After Critical Illness

for ICU Acquired Weakness

3 locations incl. Birmingham

Sponsor: Kirby Mayer

Sex: Male·Age: 18+

Code: NCT05537298·Recruiting

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A Study of EP0031 in Patients With Advanced RET-altered Malignancies

for Advanced Solid Tumor

Drug: EP0031

18 locations incl. Los Angeles

Sponsor: Ellipses Pharma

Sex: All·Age: 18+

Code: NCT05443126·Phase 1, Phase 2·Recruiting

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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

22 locations incl. Birmingham

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting

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GENOCARE: A Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care

for Colorectal Cancer

1 location in Lexington

Sponsor: Reema A. Patel

Sex: All·Age: 18+

Code: NCT05391126·Recruiting

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Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients

for Heart Failure

1 location in Lexington

Sponsor: Maya Ignaszewski

Sex: All·Age: 18+

Code: NCT05537467·Recruiting

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School Screening and Telemedicine Specialty Referral to Address Childhood Hearing Loss in Rural Kentucky

for Hearing Loss

1 location in Lexington

Sponsor: University of Arkansas

Sex: All·Age: 3 - 11·Accepts healthy volunteers

Code: NCT05513833·Recruiting

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Degenerative Cervical Myelopathy Repository

for Cervical Myelopathy

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18 - 100

Code: NCT05446259·Recruiting

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Prospective Analysis of Spinal Epidural Abscess

for Spinal Epidural Abscess

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18+

Code: NCT05464251·Recruiting

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Spinal Cord Injury Neuroprotection With Glyburide

for Acute Spinal Cord Injury

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05426681·Phase 1·Recruiting

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Abatacept in Immune Checkpoint Inhibitor Myocarditis

for Myocarditis Acute

29 locations incl. Los Angeles

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05335928·Phase 3·Recruiting

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Ultrafiltration Versus IV Diuretics in Worsening Heart Failure

for Heart Failure (for Example, Fluid Overload)

17 locations incl. Tucson

Sponsor: Nuwellis, Inc.

Sex: All·Age: 18+

Code: NCT05318105·Recruiting

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Quality Improvement Pilot

for Cancer

1 location in Lexington

Sponsor: University of Kentucky

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05415800·Enrolling By Invitation

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

25 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05316155·Phase 1, Phase 2·Recruiting

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Long-Term Follow-up Study

for Lymphoma, Non-Hodgkin

31 locations incl. Birmingham

Sponsor: Caribou Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05332054·Enrolling By Invitation

A University-Community Partnership to Reduce Exposure to Disinfection Byproducts In Appalachia

for Disinfection By-products

1 location in Lexington

Sponsor: Anna Hoover

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05172752·Recruiting

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Prospective Evaluation of Pathways for Preterm Birth

for Preterm Birth

1 location in Lexington

Sponsor: John O'Brien, MD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05246579·Recruiting

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Thoracic-Lumbar Arthrodesis- Implanet Jazz

for Spondylolisthesis

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18 - 100

Code: NCT05366140·Recruiting

Apply to this trial

Biopsy Collection and Repository Database

for Cardiovascular Diseases

1 location in Lexington

Sponsor: Kenneth S. Campbell

Sex: All·Age: 18+

Code: NCT05521503·Recruiting

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The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

for Pre-diabetes

1 location in Lexington

Sponsor: Philip Kern

Sex: All·Age: 35 - 65·Accepts healthy volunteers

Code: NCT05051436·Phase 4·Recruiting

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A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine

for Migraine

20 locations incl. New Haven

Sponsor: H. Lundbeck A/S

Sex: All·Age: 6 - 17

Code: NCT05164172·Phase 3·Recruiting

Apply to this trial