Paid Clinical Trials in Kentucky

Kentucky has 1,052 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,052 clinical trials

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Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

for Acute Respiratory Distress Syndrome

15 locations incl. Irvine

Sponsor: BioAegis Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05947955·Phase 2·Recruiting

Apply to this trial

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

for Coronary Artery Disease

18 locations incl. Glendale

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06399705·Phase 3·Recruiting

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Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Intermediate Risk Non-Muscle Invasive Bladder Cancer

Drug: Nadofaragene Firadenovec

49 locations incl. Mobile

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06510374·Phase 3·Recruiting

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Harm Reduction for Smokers With Mental Illness

for Tobacco Dependence

2 locations incl. Louisville

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 21+

Code: NCT06543407·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

76 locations incl. Anniston

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

221 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting

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Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

37 locations incl. Baltimore

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting

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A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for Breast Cancer

165 locations incl. Daphne

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06492616·Phase 3·Recruiting

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Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting

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Combination Therapy for Recurrent Ovarian Cancer

for Recurrent Ovarian Cancer

1 location in Louisville

Sponsor: Sham Sunder Kakar

Sex: Female·Age: 18+

Code: NCT05610735·Phase 1, Phase 2·Recruiting

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A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer

for Platinum-resistant Ovarian Cancer

17 locations incl. Scottsdale

Sponsor: Cybrexa Therapeutics

Sex: Female·Age: 18+

Code: NCT06315491·Phase 2·Recruiting

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A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

for Gram-negative Bacterial Infection

11 locations incl. Orange

Sponsor: Pfizer

Sex: All·Age: Up to 39 Weeks

Code: NCT06462235·Phase 2·Recruiting

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

37 locations incl. Mobile

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting

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Gastroparesis Registry 4

for Gastroparesis

6 locations incl. Scottsdale

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85

Code: NCT05846802·Recruiting

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Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

for Gastroesophageal Junction

8 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06469944·Phase 1, Phase 2·Recruiting

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

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REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

for Coronary Artery Disease

18 locations incl. Glendale

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06399692·Phase 3·Recruiting

Apply to this trial

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

167 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting

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Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for Metastatic Dedifferentiated Liposarcoma

245 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06422806·Phase 3·Recruiting

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Cannabis and Opioid Use Disorder

for Opioid Use Disorder

1 location in Lexington

Sponsor: University of Kentucky

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT05729932·Phase 1·Recruiting

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A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

104 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting

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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

168 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting

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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

64 locations incl. Dothan

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting

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A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

for Lupus Erythematosus, Systemic

19 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06581198·Phase 2·Recruiting

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A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

for Pulmonary Hypertension

31 locations incl. Phoenix

Sponsor: Tectonic Therapeutic

Sex: All·Age: 18 - 83

Code: NCT06616974·Phase 2·Recruiting

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Primary Subtalar Arthrodesis for Calcaneal Fractures

for Calcaneus Fracture

17 locations incl. Orange

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06249126·Recruiting

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LMN-201 for Prevention of C. Difficile Infection Recurrence

for Clostridioides Difficile Infection

16 locations incl. Escondido

Sponsor: Lumen Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05330182·Phase 2, Phase 3·Recruiting

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Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage

for Postpartum Hemorrhage

19 locations incl. Birmingham

Sponsor: KOKO Medical Inc.

Sex: Female·Age: 18+

Code: NCT06452355·Recruiting

Apply to this trial

Military Health and Nutrition Examination Study

for Hypertension

3 locations incl. Fort Campbell

Sponsor: Pennington Biomedical Research Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06380322·Recruiting

Apply to this trial

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Sacramento

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06352359·Phase 1·Recruiting

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A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

for Multiple Myeloma

50 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT06413498·Phase 3·Recruiting

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Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for Refractory Differentiated Thyroid Gland Carcinoma

301 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06475989·Phase 3·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: Upadacitinib

30 locations incl. Little Rock

Sponsor: AbbVie

Sex: All·Age: 2 - 11

Code: NCT06461897·Phase 3·Recruiting

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Precision Lung Cancer Survivorship Care Intervention

for Lung Cancer

1 location in Lexington

Sponsor: Jerod L Stapleton, PhD

Sex: All·Age: 18+

Code: NCT05857995·Recruiting

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Modeling Tobacco Regulatory Impacts in Appalachia Using the Experimental Tobacco Marketplace

for Tobacco Use

1 location in Lexington

Sponsor: Mikhail N Koffarnus

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06234722·Enrolling By Invitation

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

101 locations incl. Birmingham

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting

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Hearing Healthcare Assessment in Rural Communities

for Hearing Loss, Adult-Onset

9 locations incl. Campbellsville

Sponsor: Matthew Bush, MD

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05786794·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

266 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting

Apply to this trial

A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

40 locations incl. Phoenix

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting

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Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

for Gastroesophageal Junction

8 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06445972·Phase 1, Phase 2·Recruiting

Apply to this trial