Paid Clinical Trials in Iowa City, IA

As of June 2026, 591 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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591 clinical trials

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Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

for Dental Prosthesis

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 65 - 105

Code: NCT06406751·Enrolling By Invitation

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for Refractory Differentiated Thyroid Gland Carcinoma

301 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06475989·Phase 3·Recruiting

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Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals

for Dental Pulp Necroses

1 location in Iowa City

Sponsor: Abhishek Parolia

Sex: All·Age: 18 - 95

Code: NCT06569329·Recruiting

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Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

for Post Operative Pain

1 location in Iowa City

Sponsor: Melinda Seering

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT05868330·Phase 4·Recruiting

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The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

for Traumatic Lower Limb Injury

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 65

Code: NCT06127316·Recruiting

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Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for B-cell Acute Lymphoblastic Leukemia

17 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 6 Months - 25

Code: NCT06395103·Phase 1, Phase 2·Recruiting

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Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

for Electronic Cigarette Use

2 locations incl. Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT06489249·EARLY_Phase 1·Recruiting

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A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

51 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting

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Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

7 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT06544798·Phase 2·Enrolling By Invitation

Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

for Endothelial Function

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT06499844·EARLY_Phase 1·Recruiting

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Real-time Personalized Brain State-dependent TMS After Stroke

for Stroke

1 location in Iowa City

Sponsor: Sara Hussain

Sex: All·Age: 18+

Code: NCT06533176·Recruiting

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A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

for Peripheral Neuropathy

3 locations incl. San Francisco

Sponsor: Elpida Therapeutics SPC

Sex: All·Age: All ages

Code: NCT06151600·Recruiting

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

29 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

50 locations incl. Gilbert

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting

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Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

for Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

22 locations incl. Los Angeles

Sponsor: Servier Bio-Innovation LLC

Sex: All·Age: 18+

Code: NCT06127407·Phase 3·Recruiting

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From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

for Foot Injury

5 locations incl. San Diego

Sponsor: Jason Wilken

Sex: All·Age: 18 - 65

Code: NCT06352788·Recruiting

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Dime La VerDAD: Verify, Debunk, and Disseminate

for Influenza

4 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06417762·Recruiting

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Behavioral Economic & Staffing Strategies in the ICU

for Implementation Science

3 locations incl. Iowa City

Sponsor: University of Nebraska

Sex: All·Age: 19+

Code: NCT06184945·Recruiting

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Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

13 locations incl. San Francisco

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

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Paced Heart Rate Acceleration for Cardiac Conditioning

for Heart Failure, Systolic

1 location in Iowa City

Sponsor: Denice Hodgson-Zingman, MD

Sex: All·Age: 18 - 120

Code: NCT06332391·Recruiting

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

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Essential Amino Acid Supplementation for Femoral Fragility Fractures

for Femoral Fracture

2 locations incl. Iowa City

Sponsor: Michael C Willey

Sex: All·Age: 65+

Code: NCT06050668·Phase 2·Recruiting

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

22 locations incl. Phoenix

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting

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Spastic Paraplegia - Centers of Excellence Research Network

for Hereditary Spastic Paraplegia

11 locations incl. Miami

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06553976·Recruiting

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Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

for Metastatic Breast Cancer

29 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06324357·Phase 1, Phase 2·Recruiting

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A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

for Leukemia, Lymphocytic, Chronic, B-Cell

Drug: Ibrutinib

32 locations incl. Cerritos

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05963074·Phase 2·Recruiting

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A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

for Pediatric

Drug: Aficamten

26 locations incl. Phoenix

Sponsor: Cytokinetics

Sex: All·Age: 12 - 17

Code: NCT06412666·Phase 2, Phase 3·Recruiting

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Multi-Center Clean Air Randomized Controlled Trial in COPD

for Chronic Obstructive Pulmonary Disease (COPD)

11 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 40+

Code: NCT06376994·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

135 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting

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CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

for End-Stage Kidney Disease

8 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05931276·Phase 3·Recruiting

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Neuronal and Network Mechanisms of Electrocortical Stimulation

for Epilepsy

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT06391294·Enrolling By Invitation

Treatment Targets in Spanish and English Bilingual Speech Intervention

for Speech Sound Disorder

1 location in Iowa City

Sponsor: Philip Combiths

Sex: All·Age: 3 - 8

Code: NCT06416306·Phase 1·Recruiting

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Preventing Injured Knees From osteoArthritis: Severity Outcomes

for Osteoarthritis, Knee

9 locations incl. Atlanta

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 45

Code: NCT06096259·Phase 2·Recruiting

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177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry

for Neuroendocrine Tumors

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18+

Code: NCT06395402·Phase 2·Recruiting

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The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

for Adverse Childhood Experiences

1 location in Iowa City

Sponsor: Nathaniel Jenkins

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT06454344·Recruiting

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A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

for Atrial Fibrillation

35 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06335082·Enrolling By Invitation

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

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Concurrent TMS-fMRI

for Healthy Control

1 location in Iowa City

Sponsor: Jing Jiang

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06633913·Recruiting

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

22 locations incl. Englewood

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting

Apply to this trial