Paid Clinical Trials in Iowa City, IA

As of June 2026, 591 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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591 clinical trials

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

32 locations incl. Huntsville

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting

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Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for Small Cell Lung Carcinoma

4 locations incl. Iowa City

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07006727·Phase 1·Recruiting

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A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

for Chronic Lymphocytic Leukemia (CLL)

13 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07221500·Phase 2·Recruiting

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EnDOvascular Therapy for Late WiNdow IschEmic Stroke Patients Selected bY AutoMatic Plain ComputErized Tomography

for Stroke Acute

1 location in Iowa City

Sponsor: Santiago Ortega Gutierrez

Sex: All·Age: 18 - 80

Code: NCT07001852·Recruiting

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Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

for Adverse Childhood Experience

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT07244809·Recruiting

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A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel

for Multiple Myeloma

5 locations incl. San Francisco

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 80

Code: NCT07149857·Phase 2·Recruiting

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T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas

for Malignant Glioma

1 location in Iowa City

Sponsor: John M. Buatti

Sex: All·Age: 21+

Code: NCT07447531·Recruiting

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

20 locations incl. Orange

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting

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Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

for Acute Myeloid Leukemia (AML)

42 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07007312·Phase 3·Recruiting

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Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy

for Factor VIII Deficiency

4 locations incl. Los Angeles

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT06941870·Phase 4·Recruiting

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IH, Brain Health, and T2D

for Type 2 Diabetes

1 location in Iowa City

Sponsor: Darren P Casey

Sex: All·Age: 60 - 85·Accepts healthy volunteers

Code: NCT07173543·Recruiting

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Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

18 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting

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A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

for Spinal Muscular Atrophy

Drug: Apitegromab

14 locations incl. Phoenix

Sponsor: Scholar Rock, Inc.

Sex: All·Age: Up to 2

Code: NCT07047144·Phase 2·Recruiting

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A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

50 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting

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Using Xe MRI to Guide Radiation Therapy for Lung Cancer

for Imaging Techniques

1 location in Iowa City

Sponsor: Sean Fain

Sex: All·Age: 18 - 80

Code: NCT06925295·Phase 2·Recruiting

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Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

for IgAN

11 locations incl. Doral

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06989359·Phase 2·Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy

for Gestational Diabetes Mellitus (GDM)

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06911372·Phase 1·Recruiting

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A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for Urothelial Carcinoma Bladder

9 locations incl. Duarte

Sponsor: Aktis Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07020117·Phase 1·Recruiting

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Progressive Achilles Loading Via Clinician E-support

for Achilles Tendon Pain

2 locations incl. Iowa City

Sponsor: Ruth Chimenti

Sex: All·Age: 18 - 60

Code: NCT06736795·Recruiting

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Harnessing Communication Preferences

for Intellectual Disability

2 locations incl. Athens

Sponsor: Joel E. Ringdahl

Sex: All·Age: 2 - 90

Code: NCT07278544·Recruiting

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A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

17 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06948318·Phase 3·Recruiting

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Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

for COPD Acute Exacerbation

22 locations incl. Birmingham

Sponsor: Connect Biopharm LLC

Sex: All·Age: 40 - 80

Code: NCT06940154·Phase 2·Recruiting

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Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)

for Asthma Acute

18 locations incl. Palo Alto

Sponsor: Connect Biopharm LLC

Sex: All·Age: 12 - 75

Code: NCT06940141·Phase 2·Recruiting

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Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for Multiple Myeloma, Newly Diagnosed

11 locations incl. Birmingham

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 19+

Code: NCT06974786·Phase 2·Recruiting

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Adenosine vs Diltiazem for Treatment of SVT in the ED

for Supraventricular Tachycardia (SVT)

1 location in Iowa City

Sponsor: Anne E. Zepeski

Sex: All·Age: 18 - 100

Code: NCT06993038·Phase 4·Recruiting

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

13 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting

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A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease

for Fabry Disease

6 locations incl. Phoenix

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 2 - 17

Code: NCT06328608·Phase 2, Phase 3·Recruiting

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A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

31 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting

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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

for Colon Adenocarcinoma

Drug: Calderasib

26 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06997497·Phase 3·Recruiting

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AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

Drug: Rituximab

31 locations incl. Tuscaloosa

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

for Ulcerative Colitis

21 locations incl. Escondido

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06975722·Phase 2·Recruiting

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Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for Prostate Cancer

25 locations incl. Palo Alto

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06855277·Phase 3·Recruiting

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SMBP Study: Improving High Blood Pressure in Older Adults With Multiple Chronic Diseases

for Hypertension

2 locations incl. Iowa City

Sponsor: Korey Kennelty

Sex: All·Age: 65+

Code: NCT06932029·Recruiting

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Robotic-Assisted Versus Manual Electrode Array Insertion

for Cochlear Implantation

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 80

Code: NCT06951594·Recruiting

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E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

332 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor Malignancies

15 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06994806·Phase 1·Recruiting

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

149 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting

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Effect of Custom Dynamic Orthoses on Forefoot Loading

for Lower Extremity Injuries

2 locations incl. Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 65

Code: NCT06710119·Recruiting

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Neonatal Platelet Transfusion Threshold Trial

for Thrombocytopenia

20 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 1 Hour - 48 Hours·Accepts healthy volunteers

Code: NCT06676904·Recruiting

Apply to this trial