Paid Clinical Trials in Illinois

Illinois has 2,953 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,953 clinical trials

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Flow Detection in Open and Closed Shunt Valve Periods

for Hydrocephalus

1 location in Peoria

Sponsor: Rhaeos, Inc.

Sex: All·Age: All ages

Code: NCT07478926·Recruiting

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Integrating MOUD in Nonmedical Community Settings (Better Together)

for Opioid Use Disorder

4 locations incl. Washington D.C.

Sponsor: Howard University

Sex: All·Age: 16+

Code: NCT06416020·Not Yet Recruiting

Evaluation of the Rigicon Infla10® Inflatable Penile Prosthesis (IPP) for Erectile Dysfunction

for Erectile Dysfunction (ED)

7 locations incl. Coral Gables

Sponsor: Rigicon, Inc.

Sex: Male·Age: 22+

Code: NCT07273773·Recruiting

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Supporting Caregivers Following Mental Health Emergency Department Visits

for Caregiver Participation

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 10 - 17

Code: NCT07411300·Recruiting

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Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

3 locations incl. Dothan

Sponsor: AbbVie

Sex: All·Age: 40+

Code: NCT07230288·Phase 2·Recruiting

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Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

for Bipolar I Disorder

26 locations incl. Bentonville

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07494305·Phase 2·Recruiting

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ECHO Diabetes FQHC

for Diabetes

2 locations incl. Miami

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT07417865·Recruiting

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EVR and EPO for Liver Transplant Tolerance

for Liver Transplant

3 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06832189·Phase 1·Recruiting

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A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for Multiple Myeloma

11 locations incl. Goodyear

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225738·Recruiting

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A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

13 locations incl. Little Rock

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting

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A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis

for Dermatitis, Atopic

12 locations incl. Houston

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07230860·Phase 2·Recruiting

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Prospective HemorrhoIdaL EmboliSation (PILES) Registry

for Hemorrhoid

1 location in Libertyville

Sponsor: Joint & Vascular Institute

Sex: All·Age: 18+

Code: NCT07635784·Recruiting

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Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

for Non-small Cell Lung Cancer

29 locations incl. Fresno

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07195695·Phase 3·Recruiting

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Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs

for Diabetes Mellitus

3 locations incl. San Luis Obispo

Sponsor: California Polytechnic State University-San Luis Obispo

Sex: Female·Age: 18+

Code: NCT06988306·Recruiting

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Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

for Malignant Digestive System Neoplasm

58 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07215624·Recruiting

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A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

for Chronic Inducible Urticaria

26 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07266402·Phase 3·Recruiting

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Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

for Paroxysmal AF

15 locations incl. Jonesboro

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 80

Code: NCT07308847·Recruiting

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A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Searcy

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07321873·Phase 2·Recruiting

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Sleep, Dreaming, and Virtual Reality for Mental Health

for Anxiety

2 locations incl. Evanston

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07408206·EARLY_Phase 1·Recruiting

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Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones

for Choledocholithiasis

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 19 - 85

Code: NCT07418112·Phase 4·Recruiting

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Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

for Multiple Sclerosis

Drug: Frexalimab

21 locations incl. Cullman

Sponsor: Sanofi

Sex: All·Age: 18 - 60

Code: NCT07325292·Phase 3·Recruiting

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Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease

for Sickle Cell Disease

4 locations incl. Chicago

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06919224·Recruiting

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Thera-Clean® Microbubbles System in Patients With Skin Diseases

for Epidermolysis Bullosa

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 2+

Code: NCT07050810·EARLY_Phase 1·Enrolling By Invitation

A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis

for CKD

19 locations incl. Chula Vista

Sponsor: Renibus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07355062·Phase 3·Recruiting

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A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

for Chronic Idiopathic Constipation (CIC)

Drug: Tenapanor

109 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 18 - 80

Code: NCT07382167·Phase 3·Recruiting

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Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

for Help-Seeking Behavior

2 locations incl. San Francisco

Sponsor: San Francisco State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07475702·Recruiting

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Family Navigator Plus for Foster Parents

for Intervention

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06978959·Recruiting

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

38 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting

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PATH (Peer Advanced Training in Harm Reduction) to Reducing Burnout Among Peers Who Deliver Harm Reduction Services (R61 Phase Pilot)

for Burnout

1 location in Chicago

Sponsor: Chestnut Health Systems

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07218562·Phase 2·Enrolling By Invitation

Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

for Obesity With Diabetes

34 locations incl. Cullman

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284901·Phase 3·Recruiting

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Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

for Atrial Fibrillation

5 locations incl. Rockford

Sponsor: Javelin Medical

Sex: All·Age: 18+

Code: NCT05723926·Recruiting

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Assessing Post-operative Outcomes After Children's Sistrunk Procedure With or Without a Drain

for Thyroglossal Duct Cysts

5 locations incl. Los Angeles

Sponsor: University of Rochester

Sex: All·Age: 3 - 17

Code: NCT07148895·Enrolling By Invitation

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

for Acute Lymphoblastic Leukaemia

6 locations incl. Decatur

Sponsor: AstraZeneca

Sex: All·Age: 16+

Code: NCT07155226·Phase 1, Phase 2·Recruiting

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Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

for Diabetic Kidney Disease (DKD)

51 locations incl. Huntsville

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT07271186·Phase 2·Recruiting

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A Study of AZD0120 in Autoimmune Diseases

for Systemic Sclerosis

8 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07295847·Phase 1·Recruiting

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Clinical Outcome Assessment for AT & BCI

for Spinal Cord Injury

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07407725·Recruiting

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A Study in Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

8 locations incl. Monterey

Sponsor: N-Power Medicine

Sex: All·Age: 18+

Code: NCT07174388·Recruiting

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A Novel mHealth Intervention to Improve Outcomes of Children With Medical Complexity

for Children With Medical Complexity

2 locations incl. Chicago

Sponsor: University of Utah

Sex: All·Age: 1 - 18

Code: NCT06883045·Recruiting

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Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Advanced Non-Small Cell Lung Cancer

Drug: PF-08634404

184 locations incl. Bullhead City

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07222566·Phase 3·Recruiting

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Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for Lymphoma Diffuse Large B-cell

5 locations incl. Chicago

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284433·Phase 1, Phase 2·Recruiting

Apply to this trial