Paid Clinical Trials in Iowa

Iowa has 822 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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822 clinical trials

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Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

for PDAC

18 locations incl. Scottsdale

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06922591·Phase 1, Phase 2·Recruiting

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

137 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for Prostate Cancer (Adenocarcinoma)

350 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06592924·Phase 3·Recruiting

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A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

for Malignant Neoplasm

17 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 Month - 17

Code: NCT06941272·Phase 1, Phase 2·Recruiting

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Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

for Small-cell Lung Cancer

52 locations incl. Multiple Locations

Sponsor: Addario Lung Cancer Medical Institute

Sex: All·Age: 18+

Code: NCT06486428·Recruiting

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QUANTIFY: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

for Plantar Fasciopathy

1 location in Iowa City

Sponsor: Ruth Chimenti

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06803056·Recruiting

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Motor Outcomes to Validate Evaluations in Pediatric FSHD (MOVE Peds)

for Muscular Dystrophy, Facioscapulohumeral

6 locations incl. Palo Alto

Sponsor: University of Kansas Medical Center

Sex: All·Age: 5 - 17

Code: NCT06847282·Recruiting

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

36 locations incl. Birmingham

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting

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E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

for Care Giving Burden

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT07032350·Recruiting

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A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

for Heart Failure

Drug: Empagliflozin

105 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06935370·Phase 3·Recruiting

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Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for Central Line Associated Blood Stream Infections (CLABSI)

17 locations incl. Los Angeles

Sponsor: CorMedix

Sex: All·Age: 18+

Code: NCT06822426·Phase 3·Recruiting

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Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

for LAMA2-MD \(Merosin Deficient Congenital Muscular Dystrophy, MDC1A\)

14 locations incl. Los Angeles

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 5

Code: NCT06503367·Recruiting

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Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

18 locations incl. Phoenix

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting

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Mirikizumab Real World Protocol

for Ulcerative Colitis

8 locations incl. Denver

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT06696014·Recruiting

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Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

13 locations incl. Scottsdale

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting

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Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

for Sensorineural Hearing Loss

3 locations incl. Englewood

Sponsor: Cochlear

Sex: All·Age: 18+

Code: NCT06936449·Recruiting

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A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

for Advanced Lung Cancer

16 locations incl. Phoenix

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06892548·Phase 1, Phase 2·Recruiting

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A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

for Systemic Lupus Erythematosus

7 locations incl. Anniston

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT06916806·Phase 1·Recruiting

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

54 locations incl. Birmingham

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting

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Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

40 locations incl. Ames

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06232044·Phase 1, Phase 2·Recruiting

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A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

for RSV Infection

81 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 0+·Accepts healthy volunteers

Code: NCT06866405·Phase 3·Recruiting

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

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Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

16 locations incl. Burbank

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting

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A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for Lymphoma, Large B-Cell, Diffuse

Drug: Polatuzumab Vedotin

70 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06890884·Phase 2·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for Carcinoma, Non-Small Cell Lung

Drug: Rilvegostomig

37 locations incl. La Mesa

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06868277·Phase 3·Recruiting

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Home-Based Monitoring in Parkinson's Disease

for Parkinson Disease

1 location in Iowa City

Sponsor: Jacob E. Simmering

Sex: All·Age: 50 - 110

Code: NCT06573762·Recruiting

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PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department

for Supraventricular Tachycardia (SVT)

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 100

Code: NCT07086560·Recruiting

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

243 locations incl. Jonesboro

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting

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Early Angiotensin II in the Emergency Department

for Septic Shock

1 location in Iowa City

Sponsor: Brett A Faine

Sex: All·Age: 18 - 99

Code: NCT06693726·Phase 4·Recruiting

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

18 locations incl. Torrance

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting

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Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for Metastatic Head and Neck Squamous Cell Carcinoma

177 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06589804·Phase 3·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

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ACEs, SIRT1, and Premature Vascular Aging in Humans

for Adverse Childhood Experiences

1 location in Iowa City

Sponsor: Nathaniel Jenkins

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT07073352·Recruiting

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

55 locations incl. Bakersfield

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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Chronic Lung Allograft Dysfunction MRI Study

for Chronic Lung Allograft Dysfunction Lung MRI (CLAD)

1 location in Iowa City

Sponsor: Sean Fain

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06406777·Phase 1, Phase 2·Recruiting

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Barriers and Facilitators to OTC Hearing Aids Success

for Hearing Loss, Sensorineural

2 locations incl. Iowa City

Sponsor: Yu-Hsiang Wu

Sex: All·Age: 18 - 89

Code: NCT06499805·Recruiting

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Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers

for Nephrolithiasis

1 location in Iowa City

Sponsor: Ryan L Steinberg

Sex: All·Age: 18 - 90

Code: NCT06974357·Recruiting

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Post-Filter Hematocrit

for Continuous Renal Replacement Therapy

1 location in Iowa City

Sponsor: Gwyndolyn M. Radford

Sex: All·Age: 18+

Code: NCT07293936·Recruiting

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Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

Apply to this trial