Early Angiotensin II in the Emergency Department

Part of paid clinical trials in Iowa City, Iowa.

Sponsor
Brett A Faine
Study ID
NCT06693726
Phase
PHASE4
Status
Recruiting
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Conditions

  • Septic Shock

Eligibility Criteria

Sex
ALL
Age
18 Years - 99 Years
Healthy Volunteers
Not accepted

Interventions

  • Angiotensin II Infusion — DRUG
    Angiotensin II continuous infusion

Study Details

This pilot study will enroll 20 patients with septic shock and require emergent vasopressor support in the emergency department (ED). The primary objective of the study is to determine the feasibility of early peripheral administration of angiotensin II for treatment of septic shock in the ED

Key Dates

Start date
Apr 1, 2025
Status verified
Mar 2026
Primary completion
Aug 31, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
20 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Angiotensin II Infusion

Primary Outcome Measure

Feasibility of completing all clinical trial activities [ Time Frame: From enrollment to the end of treatment up to 6 hours after the angiotensin II infusion is initiated ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Iowa Hospitals and ClinicsIowa CityIowa52242
Brett Faine
[email protected]
3193108067

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By research site
University of Iowa Hospitals and Clinics· Iowa City, IA

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