Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

Part of paid clinical trials in Houston, Texas.

Sponsor
The University of Texas Health Science Center, Houston
Study ID
NCT01315782
Status
Not Yet Recruiting

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Conditions

  • Multi-organ Failure
  • Sepsis
  • Septic Shock
  • Severe Sepsis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This is an observational study to understand the changes in alveolar dead space in medical critically ill patients with severe infection (severe sepsis) requiring mechanical ventilation and the possibility to predict multi-organ failure. The measurement of alveolar dead space used to require sophisticated equipment and time. New ventilators have microprocessors that allow rapid mathematical calculation with minimal intervention.

Key Dates

Start date
Dec 31, 2026
Status verified
Jun 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
30 participants (estimated)

Arms

  • Arm: Multi-organ failure
    Alveolar dead space on mechanically ventilated patients with severe sepsis or septic shock.

Primary Outcome Measure

Multi-organ failure [ Time Frame: daily for 48 hours then weekly for 2 weeks. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Memorial Hermann HospitalHoustonTexas77030
Rosa M Estrada-Y-Martin, MD MSc
[email protected]
713-500-6830

Find similar trials in Houston, TX

By research site
Memorial Hermann Hospital· Houston, TX

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