Paid Clinical Trials in Huntsville, AL

As of June 2026, 90 paid clinical trials are recruiting in Huntsville, Alabama. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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90 clinical trials

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

72 locations incl. Decatur

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting

Apply to this trial

Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

34 locations incl. Birmingham

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for Staphylococcus Aureus

43 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06749457·Phase 1, Phase 2·Recruiting

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

150 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting

Apply to this trial

A Clinical Registry to Demonstrate the Safety and Performance of Teleflex Vascular Access Devices

for Vascular Access Device

3 locations incl. Huntsville

Sponsor: Teleflex

Sex: All·Age: All ages

Code: NCT06604039·Recruiting

Apply to this trial

Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

for Healthy Aging

1 location in Huntsville

Sponsor: Nutraceuticals Research Institute

Sex: All·Age: 40 - 65·Accepts healthy volunteers

Code: NCT06919328·Recruiting

Apply to this trial

Effects of Ashwagandha Extract on Stress Levels

for Stress

1 location in Huntsville

Sponsor: Nutraceuticals Research Institute

Sex: Female·Age: 30 - 59·Accepts healthy volunteers

Code: NCT06793891·Recruiting

Apply to this trial

A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

71 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting

Apply to this trial

A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease

for Alzheimer Disease

Drug: Donanemab

1 location in Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 60+

Code: NCT06566170·Recruiting

Apply to this trial

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

for Migraine

16 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 70

Code: NCT06602479·Phase 2·Recruiting

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Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

for Migraine

Drug: Ubrogepant

103 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06417775·Phase 3·Recruiting

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EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

41 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting

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A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

51 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting

Apply to this trial

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

87 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting

Apply to this trial

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

for Cardiovascular Risk

Drug: Ziltivekimab

208 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06118281·Phase 3·Recruiting

Apply to this trial

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

84 locations incl. Huntsville

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting

Apply to this trial

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

166 locations incl. Alexander City

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting

Apply to this trial

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for Aortic Stenosis

Drug: Pelacarsen

37 locations incl. Huntsville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 80

Code: NCT05646381·Phase 2·Recruiting

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

234 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

Apply to this trial

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

77 locations incl. Birmingham

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting

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A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

91 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06119581·Phase 3·Recruiting

Apply to this trial

Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

178 locations incl. Alexander City

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting

Apply to this trial

Long-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Migraine

for Migraine Prophylaxis

Drug: Atogepant

35 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05707949·Phase 3·Enrolling By Invitation

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

184 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05636176·Phase 3·Recruiting

Apply to this trial

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

for Major Depressive Disorder

24 locations incl. Huntsville

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18 - 65

Code: NCT05850689·Phase 3·Recruiting

Apply to this trial

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for Episodic Migraine

Drug: Atogepant

42 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05711394·Phase 3·Recruiting

Apply to this trial

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

for Waldenstrom Macroglobulinemia

7 locations incl. Huntsville

Sponsor: BeiGene

Sex: All·Age: 18+

Code: NCT05640102·Recruiting

Apply to this trial

Hybrid Type I Effectiveness-Implementation Trial of a Social Network Support Intervention

for HIV Seropositivity

7 locations incl. Birmingham

Sponsor: University of Chicago

Sex: All·Age: 18 - 49·Accepts healthy volunteers

Code: NCT05723653·Recruiting

Apply to this trial

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

Apply to this trial

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for Atherosclerotic Cardiovascular Disease in Patients With ESKD

Drug: Clazakizumab

164 locations incl. Decatur

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT05485961·Phase 2, Phase 3·Recruiting

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Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

for Major Depressive Disorder

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 10 - 24·Accepts healthy volunteers

Code: NCT05437588·Recruiting

Apply to this trial

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

Apply to this trial

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

for Proteinuric Kidney Disease

227 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 10 - 65

Code: NCT05312879·Phase 2, Phase 3·Recruiting

Apply to this trial

Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17)

for Migraine

Drug: Ubrogepant

109 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05127954·Phase 3·Enrolling By Invitation

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for Migraine

Drug: Ubrogepant

125 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05125302·Phase 3·Recruiting

Apply to this trial

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

for Type 2 Diabetes Mellitus

79 locations incl. Huntsville

Sponsor: Prokidney

Sex: All·Age: 30 - 80

Code: NCT05099770·Phase 3·Recruiting

Apply to this trial

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

Apply to this trial

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

Apply to this trial

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

for Heart Failure, Congestive

1 location in Huntsville

Sponsor: Heart Center Research, LLC

Sex: All·Age: 19+

Code: NCT06218199·Phase 4·Recruiting

Apply to this trial