Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

Part of paid clinical trials in Huntsville, Alabama.

Sponsor
Nutraceuticals Research Institute
Study ID
NCT06919328
Status
Recruiting
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Conditions

  • Healthy Aging

Eligibility Criteria

Sex
ALL
Age
40 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Niagen® — DIETARY_SUPPLEMENT
    nicotinamide riboside
  • NAD+ — OTHER
    Nicotinamide adenine dinucleotide
  • Placebo — OTHER
    bacteriostatic water

Study Details

This study evaluates the subjective effects of injection administration of NR on healthy adult populations.

Key Dates

Start date
Oct 31, 2024
Status verified
Apr 2025
Primary completion
Apr 30, 2025
Completion
Jun 30, 2025

Study Design

Enrollment
70 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: NR via IM injection
    100mg NR 2ml bacteriostatic water via intramuscular (IM) injection
  • Experimental: NR via subcutaneous injection
    100mg NR 2ml bacteriostatic water via subcutaneous (SQ) injection
  • Experimental: NR via IV push
    100mg NAD+ 2ml bacteriostatic water via intravenous push (IVP) injection
  • Active Comparator: NAD+ via IM injection
    100mg NAD+ in 2ml bacteriostatic water via intramuscular (IM) injection
  • Active Comparator: NAD+ via subcutaneous injection
    100mg NAD+ in 2ml bacteriostatic water via subcutaneous (SQ) injection
  • Active Comparator: NAD+ via IV push
    100mg NAD+ 2ml bacteriostatic water via intravenous push (IVP) injection
  • Placebo Comparator: placebo via IM injection
    2ml bacteriostatic water via intramuscular (IM) injection
  • Placebo Comparator: placebo via subcutaneous injection
    2ml bacteriostatic water via subcutaneous (SQ) injection
  • Placebo Comparator: placebo via IV push
    2ml bacteriostatic water via intravenous push (IVP) injection

Primary Outcome Measure

McGill Pain Questionnaire [ Time Frame: 1 minute after injection is complete ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Nutraceuticals Research InstituteHuntsvilleAlabama35801
JESSIE HAWKINS, PhD
[email protected]
2562039010

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