Clinical Trials at Texas Children's Hospital

As of June 2026, 120 paid clinical trials are recruiting at Texas Children's Hospital, located at 6621 FANNIN ST, HOUSTON, TX 77030-2303, phone (832) 824-1000 in Houston, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

120 clinical trials at Texas Children's Hospital

·Clear filters·↓ Download CSV

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

23 locations incl. Los Angeles

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting

Apply to this trial

Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells

for T-cell Acute Lymphoblastic Lymphoma

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 75

Code: NCT03690011·Phase 1·Recruiting

Apply to this trial

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

8 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting

Apply to this trial

A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for Low-grade Glioma

14 locations incl. San Francisco

Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All·Age: 6 Months - 25

Code: NCT04775485·Phase 2·Recruiting

Apply to this trial

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for Langerhan's Cell Histiocytosis

12 locations incl. Phoenix

Sponsor: Carl Allen

Sex: All·Age: All ages

Code: NCT04079179·Phase 2·Recruiting

Apply to this trial

Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia

for Propionic Acidemia

15 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: All ages

Code: NCT04159103·Phase 1, Phase 2·Recruiting

Apply to this trial

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

10 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting

Apply to this trial

VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

for Autoimmune Diseases

4 locations incl. Louisville

Sponsor: University of Louisville

Sex: All·Age: 0 - 60

Code: NCT03953768·Recruiting

Apply to this trial

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

Apply to this trial

TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

for Viral Infection

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: All ages

Code: NCT04013802·Phase 1·Recruiting

Apply to this trial

ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)

for Acute Respiratory Distress Syndrome

76 locations incl. Birmingham

Sponsor: University of Michigan

Sex: All·Age: 14 Days - 20

Code: NCT05388708·Recruiting

Apply to this trial

Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

for Congenital Heart Disease in Children

9 locations incl. Los Angeles

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04604418·Recruiting

Apply to this trial

Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas

for Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 - 75

Code: NCT04288726·Phase 1·Recruiting

Apply to this trial

HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

18 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting

Apply to this trial

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

for Diffuse Intrinsic Pontine Glioma

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 Months - 25

Code: NCT04099797·Phase 1·Recruiting

Apply to this trial

Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block

for Heart Block Complete

12 locations incl. Phoenix

Sponsor: The Hospital for Sick Children

Sex: Female·Age: 16 - 50

Code: NCT04559425·Recruiting

Apply to this trial

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

for Bronchopulmonary Dysplasia

26 locations incl. Little Rock

Sponsor: OHB Neonatology Ltd.

Sex: All·Age: 0 Hours - 24 Hours

Code: NCT03253263·Phase 2·Recruiting

Apply to this trial

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

for Malignant Solid Tumors

3 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT03739827·Recruiting

Apply to this trial

A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or Casimersen in Routine Clinical Practice

for Duchenne Muscular Dystrophy

20 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06606340·Enrolling By Invitation

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

37 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting

Apply to this trial

A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

for Chondral Defect

12 locations incl. Palo Alto

Sponsor: Vericel Corporation

Sex: All·Age: 10 - 17

Code: NCT03588975·Phase 3·Recruiting

Apply to this trial

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

Apply to this trial

Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane

for Pediatric Anesthesia

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 Month - 36 Months·Accepts healthy volunteers

Code: NCT03384563·Phase 4·Recruiting

Apply to this trial

GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma

for Neuroblastoma

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 21

Code: NCT03294954·Phase 1·Recruiting

Apply to this trial

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

for T-cell Acute Lymphoblastic Lymphoma

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 75

Code: NCT03081910·Phase 1·Recruiting

Apply to this trial

CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

for Hodgkin's Lymphoma

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 12 - 75

Code: NCT02917083·Phase 1·Recruiting

Apply to this trial

A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects

for Benign Centrally-Located Intracranial Tumors

3 locations incl. Washington D.C.

Sponsor: InSightec

Sex: All·Age: 5 - 22

Code: NCT03028246·Recruiting

Apply to this trial

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

for Aortic Aneurysm

14 locations incl. Newport Beach

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04005976·Recruiting

Apply to this trial

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

61 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting

Apply to this trial

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

for Langerhans Cell Histiocytosis

11 locations incl. Palo Alto

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 21

Code: NCT02670707·Phase 3·Recruiting

Apply to this trial

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

52 locations incl. Phoenix

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting

Apply to this trial

Simple Bone Cysts in Kids

for Bone Cyst

11 locations incl. Birmingham

Sponsor: The Hospital for Sick Children

Sex: All·Age: 2 - 21

Code: NCT02193841·Phase 3·Recruiting

Apply to this trial

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

for Non-Hodgkin Lymphoma

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 75

Code: NCT01853631·Phase 1·Recruiting

Apply to this trial

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

for Hodgkin's Disease

3 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: All ages

Code: NCT01555892·Phase 1·Recruiting

Apply to this trial

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

for Legg Calve Perthes Disease

28 locations incl. Birmingham

Sponsor: Texas Scottish Rite Hospital for Children

Sex: All·Age: 1 - 18

Code: NCT02040714·Enrolling By Invitation

Ex Vivo T-Cell Depletion of Mobilized Peripheral Blood Stem Cells Via CD34-Selection

for Stem Cell Transplant

2 locations incl. Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 70

Code: NCT01189786·Recruiting

Apply to this trial

Natural History Study of SCID Disorders

for Severe Combined Immunodeficiency (SCID)

39 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT01186913·Enrolling By Invitation

HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

for Pediatric Hydrocephalus

11 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: Up to 18

Code: NCT00670735·Recruiting

Apply to this trial

The Pediatric Anesthesia Quality Improvement Project

for Surgery

37 locations incl. Phoenix

Sponsor: The Society for Pediatric Anesthesia

Sex: All·Age: Up to 21

Code: NCT00674388·Recruiting

Apply to this trial

Childhood Cancer Survivor Study

for Cancer

30 locations incl. Birmingham

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting

Apply to this trial