Heart disease Clinical Trials in Houston, TX

As of June 2026, 67 paid clinical trials are recruiting for Heart disease in Houston, Texas. Heart disease research tests new drug therapies, device-based interventions, and lifestyle programs for heart failure, atrial fibrillation, hypertension, and coronary disease — including therapies that reduce hospitalization and cardiovascular death. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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67 clinical trials for Heart disease

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for Heart Failure

20 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 29 Days - 17

Code: NCT05714085·Phase 2, Phase 3·Recruiting

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A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

184 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05636176·Phase 3·Recruiting

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

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Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

for Dyslipidemias

Drug: Bempedoic acid

3 locations incl. Los Angeles

Sponsor: Priscilla Hsue, MD

Sex: All·Age: 40+

Code: NCT05488431·Phase 2·Recruiting

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

150 locations incl. Birmingham

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting

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EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

for Heart Failure

15 locations incl. Los Angeles

Sponsor: Berlin Heart, Inc

Sex: All·Age: Up to 21

Code: NCT05610787·Enrolling By Invitation

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

for Heart Failure

12 locations incl. La Jolla

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 100

Code: NCT06425848·Recruiting

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The CONFORM Pivotal Trial

for Atrial Fibrillation

76 locations incl. Birmingham

Sponsor: Conformal Medical, Inc

Sex: All·Age: 18+

Code: NCT05147792·Recruiting

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Assessment of CCM in HF With Higher Ejection Fraction

for Heart Failure

105 locations incl. Birmingham

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT05064709·Recruiting

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Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study

for Preoperative Care

5 locations incl. Winston-Salem

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 45+

Code: NCT04973397·Recruiting

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The GUARDIAN Trial

for Blood Pressure

6 locations incl. Omaha

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 45+

Code: NCT04884802·Recruiting

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

55 locations incl. Huntsville

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines

for Cardiomyopathy

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18 - 80

Code: NCT02962661·Phase 1·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

51 locations incl. Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting

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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

for PAH

Drug: Ralinepag

48 locations incl. Phoenix

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT03683186·Phase 3·Enrolling By Invitation

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress

for Stroke

2 locations incl. Los Angeles

Sponsor: Population Health Research Institute

Sex: All·Age: 55+

Code: NCT03968393·Phase 4·Recruiting

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ATrial Tachycardia PAcing Therapy in Congenital Heart

for Atrial Arrhythmia

14 locations incl. Los Angeles

Sponsor: Ian Law

Sex: All·Age: All ages

Code: NCT03209583·Recruiting

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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for Functional Mitral Regurgitation

75 locations incl. Gilbert

Sponsor: Cardiac Dimensions, Inc.

Sex: All·Age: 18+

Code: NCT03142152·Recruiting

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Tracking Results of Ablations to Combat AF Registry Generation 2

for Atrial Fibrillation

26 locations incl. Huntsville

Sponsor: AtriCure, Inc.

Sex: All·Age: 18+

Code: NCT05111015·Recruiting

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Product Surveillance Registry

for Cardiac Rhythm Disorders

134 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting

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DeBakey Cardiovascular Magnetic Resonance Study

for Cardiovascular Diseases

1 location in Houston

Sponsor: Dipan Shah

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04281823·Recruiting

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Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

for Heart

3 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 20 - 90

Code: NCT01258231·Recruiting

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Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

113 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting

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Conditions in Heart disease (Houston, TX)

Heart failure· 31 Cardiovascular disease (general)· 15 Hypertension (high blood pressure)· 11 Atrial fibrillation· 10 Coronary artery disease· 6 Congenital heart disease· 3 Myocardial infarction (heart attack)· 2