Solid tumor Clinical Trials in Detroit, MI
As of June 2026, 62 paid clinical trials are recruiting for Solid tumor in Detroit, Michigan. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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62 clinical trials for Solid tumor
·Clear filters·↓ Download CSVMetformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
The Vanguard Study: Testing a New Way to Screen for Cancer
A Study of ZL-1310 in Participants With Selected Solid Tumors
Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors
A Phase 1 Study of BHV-1530 in Advanced Solid Tumors
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors
Study of SGR-3515 In Participants With Advanced Solid Tumors.
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
A Study of DB-1310 in Advanced/Metastatic Solid Tumors
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
A Study of ASP1002 in Adults for Treatment of Solid Tumors
To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation
Study of SGN1 in Patients With Advanced Solid Tumor
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment
A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination
JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
Study of CHS-114 in Participants With Advanced Solid Tumors
About research studies in Detroit
Detroit has approximately 810 recruiting research studies across a wide range of therapeutic areas. Michigan hosts University of Michigan Health, Henry Ford Health, and Corewell Health, running trials across oncology, neurology, and cardiology with a strong focus on precision medicine.
Top Research Study Locations in Detroit
Researchers run research studies in Detroit, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Hospital | Acute Myeloid Leukemia, Melanoma, Anatomic Stage II Breast Cancer AJCC v8 | 151 |
| Karmanos Cancer Institute | Advanced Solid Tumor, Endometrial Cancer, Ovarian Cancer | 89 |
| Henry Ford Health System | Advanced Solid Tumor, Brain Tumor, Breast Cancer | 86 |
| Henry Ford Health | Heart Failure, Advanced Solid Tumor, Amyotrophic Lateral Sclerosis | 54 |
| Wayne State University/Karmanos Cancer Institute | Malignant Solid Neoplasm, Stage III Hypopharyngeal Carcinoma AJCC v8, Stage III Laryngeal Cancer AJCC v8 | 45 |
| Children's Hospital of Michigan | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Down Syndrome | 45 |
| Henry Ford Health Saint John Hospital | Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8 | 43 |
| Wayne State University | Infant, Low Birth Weight, Infant, Newborn, Infant, Premature | 26 |
| Barbara Ann Karmanos Cancer Institute | Breast Cancer, Non-small Cell Lung Cancer, Breast Neoplasms | 23 |
| Henry Ford Cancer Institute | Metastatic Solid Tumor, Acute Leukemia, Acute Myeloid Leukemia | 13 |
| John D. Dingell VA Medical Center, Detroit, MI | Obstructive Sleep Apnea, Sleep Apnea, Sleep Disordered Breathing | 11 |
| GSK Investigational Site | Neoplasms, Colonic Neoplasms, Hepatitis B | 9 |
| Henry Ford | ADHF, Atrial Fibrillation (AF), Brain Tumor - Metastatic | 7 |
| Henry Ford Health Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Karmanos Cancer Center | Breast Neoplasms, Endometrial Cancer, Limited-stage Small Cell Lung Cancer (LS-SCLC) | 6 |
| Tolan Park Medical Building | PTSD, Polysubstance Abuse, Adolescence | 6 |
| Henry Ford St. John Hospital | Atrial Fibrillation, Cardiovascular Diseases, Coronary Artery Disease (CAD) | 5 |
| Ascension Saint John Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Cardiotoxicity, Elevated CA15-3 or CEA or CA27-29 | 4 |
| Ascension St. John Hospital | High-Risk Percutaneous Coronary Intervention, Pulmonary Embolism, Rectal Cancer | 4 |
| Clinical Trial Site | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency, Advanced Breast Cancer | 4 |
| Detroit Medical Center | Diabetes (DM), Diabetic Ketoacidosis, Gastric Emptying | 4 |
| Detroit Receiving Hospital | Traumatic Brain Injury, Lumbar Spinal Stenosis, Status Epilepticus | 4 |
| Henry Ford Cancer - Detroit (Brigitte Harris Cancer Pavilion) | Advanced Melanoma, KRAS G12C-mutated Solid Tumors, Lung Cancer, KRAS, NRAS, HRAS-mutated NSCLC | 4 |
| Henry Ford Cancer Center | Locally Advanced Solid Tumor, Hemoglobinopathy, Metastatic Solid Tumor | 4 |
| Barbara Ann Karmanos Cancer Hospital dba Karmanos Cancer Center | Advanced Solid Tumor, Cutaneous Melanoma, Endometrial Carcinoma (EC) | 3 |
Active & Upcoming Studies in Detroit (2026)
Recruiting trials in Detroit grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (367 active studies)
- A Study of the TheraBionic P1 Device in Breast Cancer · Barbara Ann Karmanos Cancer Institute
- Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer · Phase 1, Phase 2 · University of Michigan Rogel Cancer Center
Cardiovascular (48 active studies)
- Light Utilization COX-Inhibitory Device Therapy for Infant Cardiac Arrest (LUTICA Study). The LUCID Device is Used in the Treatment of Ischemic Brain Reperfusion Injury Caused by Cardiac Arrest in Pediatric Patients. · Mitovation, Inc
- A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation · Phase 2 · Bayer
Neurology & pain (32 active studies)
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers · VA Office of Research and Development
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment · Phase 4 · VA Office of Research and Development
Mental health & behavior (11 active studies)
- Peer-Delivered Behavioral Activation in a CCBHC · Wayne State University
- Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery · Phase 1 · Wayne State University
Diabetes & metabolic (10 active studies)
- Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System · Insulet Corporation
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Pediatric (6 active studies)
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
- A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). · Phase 2, Phase 3 · Cytokinetics
HIV / STI (5 active studies)
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
- Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples · Hunter College of City University of New York
Eye & vision (4 active studies)
- Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · Henry Ford Health System
- Community Based Treatment for (ComBaT) Glaucoma · University of Michigan
Vaccines (3 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- Predictors of Post-COVID-19 Clinical and Cognitive Consequences · VA Office of Research and Development
Common conditions studied in Detroit
- Advanced Solid Tumor (19 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (18 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Endometrial Cancer (18 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (14 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Multiple Myeloma (14 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ovarian Cancer (14 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
Leading research sponsors in Detroit
- Henry Ford Health System
- National Cancer Institute (NCI)
- AstraZeneca
- NRG Oncology
- Wayne State University
Local regulations and guidelines
Clinical trials in Michigan are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Michigan research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Detroit. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Detroit
Hipa.ai aggregates every recruiting study in Detroit from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Detroit?
There are approximately 810 recruiting clinical trials in Detroit, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Detroit pay participants?
Most recruiting trials in Detroit compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Detroit?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Detroit?
The most common conditions under active study in Detroit include Advanced Solid Tumor (19), Breast Cancer (18), Endometrial Cancer (18), Acute Myeloid Leukemia (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Detroit?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Detroit on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Detroit?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Detroit?
Recruiting research sites in Detroit include Henry Ford Hospital, Karmanos Cancer Institute, Henry Ford Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Detroit right now?
The largest active categories in Detroit are Cancer & tumors (367), Cardiovascular (48), Neurology & pain (32). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.