Clinical Trials at UT Southwestern Medical Center

As of June 2026, 184 paid clinical trials are recruiting at UT Southwestern Medical Center, located at UT Southwestern Medical Center: Research Department, 6000 Harry Hines Blvd, Dallas, TX 75235, phone (214) 633-0022 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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184 clinical trials at UT Southwestern Medical Center

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

Apply to this trial

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

18 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT05926765·Phase 2·Recruiting

Apply to this trial

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for Adenocarcinoma of Lung

6 locations incl. Beverly Hills

Sponsor: Lantern Pharma Inc.

Sex: All·Age: 18+

Code: NCT05456256·Phase 2·Recruiting

Apply to this trial

Multicomponent Intervention Study- Blood Donors With High Cholesterol

for Lipid Metabolism Disorder

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 75

Code: NCT05693701·Recruiting

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The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

for Lower Respiratory Tract Infection

8 locations incl. Jacksonville

Sponsor: MeMed Diagnostics Ltd.

Sex: All·Age: 18 - 99

Code: NCT05762302·Recruiting

Apply to this trial

Patients With and Without Phonotrauma

for Phonotrauma

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05625191·Recruiting

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Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria

for Cystic Fibrosis

7 locations incl. Denver

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 1 Month - 99

Code: NCT05686837·Enrolling By Invitation

Laryngeal Cryotherapy for Refractory Neurogenic Cough

for Upper-Airway Cough Syndrome

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT05665244·Recruiting

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PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

for Critical Limb Ischemia

30 locations incl. La Jolla

Sponsor: LimFlow, Inc.

Sex: All·Age: 18 - 95

Code: NCT05313165·Recruiting

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Duchenne Electronic Health Record Study

for Duchenne Muscular Dystrophy (DMD)

10 locations incl. Little Rock

Sponsor: The Duchenne Registry

Sex: All·Age: All ages

Code: NCT07609394·Recruiting

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Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

for Treatment Resistant Depression

1 location in Dallas

Sponsor: Nader Pouratian

Sex: All·Age: 21 - 70

Code: NCT03952962·Recruiting

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A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

for Subacute Cutaneous Lupus Erythematosus

61 locations incl. Anniston

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT05531565·Phase 2, Phase 3·Recruiting

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Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions

for Hypertension

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT05168605·Recruiting

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Preventing Cognitive Decline by Reducing BP Target Trial

for Cognitive Decline

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 70+

Code: NCT05106036·Recruiting

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Brain Injury Education and Outpatient Navigation-1stBIEN

for Brain Injuries, Traumatic

6 locations incl. Colorado Springs

Sponsor: Seattle Children's Hospital

Sex: All·Age: 3+

Code: NCT05261477·Recruiting

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

45 locations incl. Birmingham

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05338697·Recruiting

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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

35 locations incl. Birmingham

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting

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Longitudinal Bladder Cancer Study for Tumour Recurrence

for Urothelial Bladder Cancer

6 locations incl. Miami

Sponsor: Pacific Edge Limited

Sex: All·Age: 18+

Code: NCT05080998·Recruiting

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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for Gastric Adenocarcinoma

13 locations incl. Orange

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05365581·Phase 1·Recruiting

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RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

for Coronary Artery Disease

7 locations incl. Iowa City

Sponsor: MedTrace Pharma A/S

Sex: All·Age: 18+

Code: NCT05134012·Phase 3·Recruiting

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Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease

for Glut1 Deficiency Syndrome 1

2 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 16 - 80·Accepts healthy volunteers

Code: NCT05085704·Recruiting

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A-LiNK: Improving Outcomes in Autoimmune Liver Disease

for Autoimmune Hepatitis

8 locations incl. Palo Alto

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05750498·Recruiting

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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

for HER2-negative Breast Cancer

7 locations incl. Chicago

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05029999·Phase 1·Recruiting

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CLOZAPINE Response in Biotype-1

for Schizophrenia

5 locations incl. Hartford

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT04580134·Phase 4·Recruiting

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Motor Network Physiology

for Parkinson Disease

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 89

Code: NCT04957095·Recruiting

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Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for Relapsed or Refractory T Cell Lymphoma

20 locations incl. Birmingham

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT05079282·Phase 1·Recruiting

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

22 locations incl. Birmingham

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

Apply to this trial

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

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Markers of Osteoporosis in Cystic Fibrosis

for Cystic Fibrosis

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT03921060·Phase 4·Recruiting

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[18F]PT2385 PET/CT in Patients With Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in Dallas

Sponsor: Orhan Kemal Oz

Sex: All·Age: 18+

Code: NCT04989959·Phase 1·Recruiting

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A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

24 locations incl. Paradise Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting

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Ultra-fractionated Radiotherapy for Rectal Cancer

for Rectal Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT04677413·Phase 1·Recruiting

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DALY II USA/ MB-CART2019.1 for DLBCL

for Refractory Diffuse Large B Cell Lymphoma (DLBCL)

23 locations incl. Gilbert

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT04792489·Phase 2·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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Handoffs and Transitions in Critical Care - Understanding Scalability

for Patient Handoff

5 locations incl. Baltimore

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04571749·Enrolling By Invitation

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

for Motor Function

16 locations incl. Scottsdale

Sponsor: Guerbet

Sex: All·Age: 18 - 64

Code: NCT04373564·Phase 4·Recruiting

Apply to this trial

Youth Depression and Suicide Research Network

for Depression

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 8 - 20

Code: NCT04572321·Enrolling By Invitation

Converting HR+ Breast Cancer Into an Individualized Vaccine

for Breast Cancer

8 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18 - 90

Code: NCT03804944·Phase 2·Recruiting

Apply to this trial

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

Apply to this trial