Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease

Part of paid clinical trials in New York, New York.

Sponsor
Weill Medical College of Cornell University
Study ID
NCT05085704
Status
Recruiting
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Conditions

  • Epilepsy
  • Glucose Metabolism Disorders
  • Glucose Transport Defect
  • Glucose Transporter Protein Type 1 Deficiency Syndrome
  • Glucose Transporter Type 1 Deficiency Syndrome
  • Glut1 Deficiency Syndrome 1
  • Glut1 Deficiency Syndrome 1, Autosomal Recessive

Eligibility Criteria

Sex
ALL
Age
16 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • Magnetic resonance imaging — DEVICE
    Medical imaging technique used in radiology to form pictures of the anatomy.

Study Details

The goal is to develop methodology to monitor flux in the citric acid cycle in brain via 13C nuclear magnetic resonance (NMR) spectroscopy at 7 Tesla or 3 Tesla.

Key Dates

Start date
May 3, 2022
Status verified
May 2026
Primary completion
Jun 1, 2029
Completion
Aug 1, 2029

Study Design

Enrollment
20 participants (estimated)

Arms

  • Arm: Adolescents and adults with Glut1 deficiency
  • Arm: Normal healthy adolescents and adults

Primary Outcome Measure

Select metabolite abundance measured at 7Tfield strength [ Time Frame: Day 1, immediately after 13 C labeled isotope infusion ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Weill Cornell MedicineNew YorkNew York10065
Rocio Moron Ares, B.S.
[email protected]
212 746 3278
Juan M Pascual, M.D
[email protected]
212 746 3278
UT Southwestern Medical CenterDallasTexas75390-

Find similar trials in New York, NY

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
Weill Cornell Medicine· New York, NYUT Southwestern Medical Center· Dallas, TX

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