An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy

Part of paid clinical trials in Great Neck, New York.

Sponsor
Northwell Health
Study ID
NCT00859794
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
5 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • fMRI — OTHER
    Subjects will perform cognitive tasks during MRI scanning sessions to gather data about cognitive functions.
  • Neuropsychological Testing — OTHER
    Subjects will have a neuropsych evaluation as part of their standard of care for surgery. The research team is asking the subject to release their neuropsychological evaluations for analysis.
  • Additional electrode implantation — OTHER
    Subjects will typically have between 100-300 electrodes implanted as part of their surgery. Additional electrodes will be implanted that are able to record from smaller, more specific parts of the brain. This will allow for better understanding of how the brain is wired.
  • Electrical brain stimulation — OTHER
    Intracranial or extracranial electrodes will be used to deliver electrical brain stimulation (amplitude 0.5-8.0mA) or sham stimulation of between 0.4 and 3000 milliseconds during cognitive task periods.

Study Details

The overall goal of this project is to better understand the micro-physiology of human epilepsy and cognition using the intracranial electroencephalogram (iEEG), electrical brain stimulation, functional magnetic resonance imaging (fMRI), and histology.

Key Dates

Start date
Nov 30, 2007
Status verified
Jan 2024
Primary completion
Feb 28, 2029
Completion
Feb 28, 2029

Study Design

Enrollment
450 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Cognitive and Behavioral Testing
    Participants will participate in cognitive tasks where brain recordings and task performance will be monitored and recorded.

Primary Outcome Measure

Decrease in seizure frequency after epilepsy surgical treatment [ Time Frame: up to 4 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
Comprehensive Epilepsy Care CenterGreat NeckNew York11021-

Find similar trials in Great Neck, NY

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
Comprehensive Epilepsy Care Center· Great Neck, NY

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