Laryngeal Cryotherapy for Refractory Neurogenic Cough

Part of paid clinical trials in Dallas, Texas.

Sponsor
University of Texas Southwestern Medical Center
Study ID
NCT05665244
Status
Recruiting

Conditions

  • Upper-Airway Cough Syndrome

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Laryngeal cryotherapy — PROCEDURE
    Laryngeal cryotherapy is the therapeutic freezing of tissue in the throat to numb the overactive sensory nerves in the throat. This technique is believed to reduce cough symptoms in this study.
  • Cryoprobe — DEVICE
    Cryoprobe is FDA approved for use for the destruction of unwanted tissue along the respiratory tract

Study Details

This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure

Key Dates

Start date
Dec 26, 2022
Status verified
Jan 2026
Primary completion
Feb 28, 2027
Completion
Feb 28, 2027

Study Design

Enrollment
28 participants (estimated)

Arms

  • Arm: Upper airway cough syndrome

Primary Outcome Measure

Improved quality of life of patients suffering from chronic cough [ Time Frame: 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UT Southwestern Medical CenterDallasTexas75235
Shumon Dhar, MD
Paula Arellano-Cruz
2146488096

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