As of June 2026, 1,420 paid clinical trials are recruiting in Columbus, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Columbus offers studies at sites including Ohio State University Comprehensive Cancer Center for conditions such as Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer, Chronic Lymphocytic Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Columbus has approximately 1,420 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Researchers run research studies in Columbus, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ohio State University Comprehensive Cancer Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 248 |
| Nationwide Children's Hospital | High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Neuroblastoma | 228 |
| The Ohio State University | Heart Failure, Alzheimer's Disease, Mild Cognitive Impairment | 143 |
| Ohio State University | Coronary Artery Disease, Head and Neck Squamous Cell Carcinoma, Ovarian Cancer | 134 |
| The Ohio State University Wexner Medical Center | Follicular Lymphoma, Endometrial Cancer, Idiopathic Pulmonary Fibrosis | 77 |
| Riverside Methodist Hospital | Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Malignant Solid Neoplasm | 45 |
| Grant Medical Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Malignant Solid Neoplasm | 37 |
| Doctors Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 35 |
| The Mark H Zangmeister Center | Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 31 |
| Columbus Oncology and Hematology Associates Inc | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 30 |
| Mount Carmel East Hospital | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 30 |
| Ohio State University Wexner Medical Center | Endometrial Cancer, Abdominal Wound Dehiscence, Acute Respiratory Distress Syndrome | 24 |
| Mount Carmel Health Center West | Malignant Solid Neoplasm, Chronic Lymphocytic Leukemia, Melanoma | 22 |
| The Ohio State University Comprehensive Cancer Center | Cancer, Colorectal Cancer, CRC | 21 |
| Ohio State University Medical Center | Atrial Fibrillation, AL Amyloidosis, Acute Lymphoblastic Leukemia | 20 |
| OSU Wexner Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Acute Hypoxic Respiratory Failure | 14 |
| OhioHealth Research Institute | Atrial Fibrillation, Iliofemoral; Thrombosis, Acute Ischemic Stroke | 12 |
| The Ohio State University Medical Center | AADC Deficiency, Abdominal Aortic Aneurysm, Bone Marrow Transplant (BMT) | 12 |
| Ohio Health Research Institute | Aortic Dissection, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine | Pregnancy, High Risk, Preeclampsia, Gestational Hypertension | 9 |
| Clinical Trial Site | AQP4+ NMOSD, ATTR Amyloidosis, Atypical Hemolytic-Uremic Syndrome | 8 |
| Ohio State University Hospital | Acute Decompensated Heart Failure, Advanced Solid Tumor, Fracture Fixation | 8 |
| GSK Investigational Site | Gastrointestinal Neoplasms, HIV Infections, Hypereosinophilic Syndrome | 7 |
| Nationwide Children's Hosptial | Primary Immune Deficiency Disorder, Adenovirus, Congenital Cytomegaloviral (CMV) Disease | 7 |
| OhioHealth Riverside Methodist Hospital | Aortic Stenosis, Coronary Artery Disease, Mitral Valve Regurgitation | 7 |
Recruiting trials in Columbus grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Columbus from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 1,420 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Columbus include Breast Cancer (25), Acute Myeloid Leukemia (21), Ovarian Cancer (18), Chronic Lymphocytic Leukemia (17), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Columbus are Cancer & tumors (508), Cardiovascular (82), Neurology & pain (73). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.