Paid Clinical Trials in Cleveland, OH

As of June 2026, 1,352 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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1,352 clinical trials

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(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for Advanced Systemic Mastocytosis (AdvSM)

14 locations incl. Birmingham

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04996875·Phase 2·Recruiting

Apply to this trial

Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

for Cardiomyopathy

21 locations incl. Little Rock

Sponsor: Tenaya Therapeutics

Sex: All·Age: 0 - 18

Code: NCT05112237·Recruiting

Apply to this trial

RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

Apply to this trial

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

Apply to this trial

Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

28 locations incl. Laguna Hills

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting

Apply to this trial

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

Apply to this trial

Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

13 locations incl. Phoenix

Sponsor: Michael Pulsipher

Sex: All·Age: 0 - 25

Code: NCT04836390·Phase 2·Enrolling By Invitation

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

15 locations incl. Huntington Beach

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting

Apply to this trial

IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

for Endometrial Cancer

24 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05051722·Recruiting

Apply to this trial

EFS of the CardioMech MVRS

for Mitral Regurgitation

12 locations incl. Thousand Oaks

Sponsor: CardioMech AS

Sex: All·Age: 18+

Code: NCT04820764·Recruiting

Apply to this trial

The GUARDIAN Trial

for Blood Pressure

6 locations incl. Omaha

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 45+

Code: NCT04884802·Recruiting

Apply to this trial

The GUARDIAN Trial - Induction Agent Sub-Study

for Major Surgery

4 locations incl. Omaha

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 45+

Code: NCT04934683·Phase 4·Enrolling By Invitation

The GUARDIAN Trial - Vasopressor Sub-Study

for Blood Pressure

4 locations incl. Omaha

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 45+

Code: NCT04934748·Phase 4·Enrolling By Invitation

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

for Renal Allograft Recipients

15 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 12 - 17

Code: NCT04877288·Phase 3·Recruiting

Apply to this trial

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

24 locations incl. Paradise Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

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Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

for Liver Diseases

18 locations incl. Los Angeles

Sponsor: European Foundation for Study of Chronic Liver Failure

Sex: All·Age: 18 - 80

Code: NCT04613921·Recruiting

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Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

20 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting

Apply to this trial

Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for Cardiac Valve Disease

9 locations incl. Indianapolis

Sponsor: Corcym S.r.l

Sex: All·Age: All ages

Code: NCT05002543·Recruiting

Apply to this trial

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

for Hemophilia A With Inhibitor

21 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: 12 - 100

Code: NCT04647227·Phase 4·Recruiting

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

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Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

for Coronary Artery Disease

40 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT04451044·Enrolling By Invitation

Persona Revision Knee System Outcomes

for Arthroplasty Complications

16 locations incl. Fayetteville

Sponsor: Zimmer Biomet

Sex: All·Age: 18+

Code: NCT04821154·Recruiting

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Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

223 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting

Apply to this trial

Corneal Biomechanical Analysis Using Brillouin Microscopy

for Keratoconus

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18 - 60

Code: NCT04598932·Enrolling By Invitation

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

for HNSCC

4 locations incl. Baltimore

Sponsor: University Hospital Freiburg

Sex: All·Age: 65+

Code: NCT05337631·Recruiting

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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

for Tibial Fractures

13 locations incl. Indianapolis

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 80

Code: NCT07006675·Phase 3·Recruiting

Apply to this trial

Uterine Manipulation During Minimally Invasive Surgery for Early Stage Endometrial Cancer

for ENDOMETRIAL CANCER

5 locations incl. Cleveland

Sponsor: Anthony Costales, MD

Sex: Female·Age: 18 - 90

Code: NCT04586959·Recruiting

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Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

for Eosinophilic Esophagitis

25 locations incl. Scottsdale

Sponsor: Dr. Falk Pharma GmbH

Sex: All·Age: 18 - 75

Code: NCT06596252·Phase 3·Recruiting

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A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

for Solid Tumors

5 locations incl. Valhalla

Sponsor: Spectrum Pharmaceuticals, Inc

Sex: All·Age: 1 Month - 17

Code: NCT04570423·Phase 2·Recruiting

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

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Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

for Symptomatic Hypertrophic Cardiomyopathy (HCM)

Drug: Aficamten

52 locations incl. Birmingham

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation

A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

for Ventilator Associated Pneumonia

8 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: All ages

Code: NCT04987840·Enrolling By Invitation

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

116 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04743141·Phase 3·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

for Depression

Drug: Cariprazine

69 locations incl. Bentonville

Sponsor: AbbVie

Sex: All·Age: 10 - 17

Code: NCT04777357·Phase 3·Recruiting

Apply to this trial