Clinical Trials at University of Chicago

As of June 2026, 199 paid clinical trials are recruiting at University of Chicago, located at 5841 S MARYLAND AVE # 2115, CHICAGO, IL 60637-1447, phone (773) 702-4601 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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199 clinical trials at University of Chicago

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Nutrition for Precision Health, Powered by the All of Us

for Nutrition

14 locations incl. Birmingham

Sponsor: RTI International

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05701657·Recruiting

Apply to this trial

Tocilizumab for Acute Chest Syndrome

for Sickle Cell Disease

Drug: Tocilizumab

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 12+

Code: NCT05640271·Phase 2·Recruiting

Apply to this trial

TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

for Type 1 Diabetes

7 locations incl. Aurora

Sponsor: Emily K. Sims

Sex: All·Age: 4 - 40

Code: NCT05594563·Phase 2·Recruiting

Apply to this trial

Predict Severe Traumatic Brain Injury

for Traumatic Brain Injury

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06966713·Recruiting

Apply to this trial

BEETroot Juice to Reverse Functional Impairment in PAD

for Peripheral Artery Disease

4 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT05624125·Recruiting

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Evaluation of a Smartphone-based Screening Tool (Picterus JP) for Neonatal Jaundice (Chicago)

for Neonatal Jaundice

1 location in Chicago

Sponsor: Picterus AS

Sex: All·Age: 1 Day - 14 Days·Accepts healthy volunteers

Code: NCT05521607·Recruiting

Apply to this trial

His-Bundle Corrective Pacing in Heart Failure

for Right Bundle-Branch Block

14 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05265520·Recruiting

Apply to this trial

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

for Advanced NSCLC

Drug: Adagrasib

84 locations incl. Anchorage

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05609578·Phase 2·Recruiting

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GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

for SCLC

8 locations incl. Scottsdale

Sponsor: Y-mAbs Therapeutics

Sex: All·Age: 16+

Code: NCT05130255·Phase 1·Recruiting

Apply to this trial

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

for Diabetes

27 locations incl. Phoenix

Sponsor: Marinella Temprosa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05704309·Enrolling By Invitation

A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

for Advanced Cancer

15 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05557045·Phase 1·Recruiting

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I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy

for Non Small Cell Lung Cancer

1 location in Chicago

Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Sex: All·Age: 18+

Code: NCT05537922·Recruiting

Apply to this trial

Case Management Dyad

for HIV

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06162897·Recruiting

Apply to this trial

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

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Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

for Elevated Serum PSA

3 locations incl. Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18 - 80

Code: NCT05512754·Phase 4·Recruiting

Apply to this trial

Abatacept in Immune Checkpoint Inhibitor Myocarditis

for Myocarditis Acute

29 locations incl. Los Angeles

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05335928·Phase 3·Recruiting

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Electrophysiological Signatures of Distinct Working Memory Subprocesses That Predict Long-term Memory Success

for Memory

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 35

Code: NCT05892419·Enrolling By Invitation

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

35 locations incl. Birmingham

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting

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A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

for FSGS

54 locations incl. Birmingham

Sponsor: Dimerix Bioscience Pty Ltd

Sex: All·Age: 12 - 80

Code: NCT05183646·Phase 3·Recruiting

Apply to this trial

REMASTer: REcurrent Brain Metastases After SRS Trial

for Brain Metastases

9 locations incl. Los Angeles

Sponsor: Monteris Medical

Sex: All·Age: 18+

Code: NCT05124912·Recruiting

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Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for Non Hodgkin Lymphoma

8 locations incl. Chicago

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 13+

Code: NCT04771572·Phase 1·Recruiting

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Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

for Graft Vs Host Disease

15 locations incl. Duarte

Sponsor: Boston Children's Hospital

Sex: All·Age: 2+

Code: NCT04380740·Phase 2·Recruiting

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A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

for Multiple Myeloma

28 locations incl. Phoenix

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05201781·Phase 4·Recruiting

Apply to this trial

MRI Screening in Men at High Risk of Developing Prostate Cancer

for Prostate Cancer Screening

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT05608694·Recruiting

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CLOZAPINE Response in Biotype-1

for Schizophrenia

5 locations incl. Hartford

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT04580134·Phase 4·Recruiting

Apply to this trial

The Reducing REVISITS Study: A Cluster RCT

for COPD

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT05568043·Recruiting

Apply to this trial

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

for Heart Failure

37 locations incl. Fairhope

Sponsor: Cordio Medical

Sex: All·Age: 22+

Code: NCT06378632·Recruiting

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myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

for COPD

25 locations incl. Birmingham

Sponsor: Temple University

Sex: All·Age: 30+

Code: NCT05204888·Recruiting

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A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

for HER2-positive Advanced Solid Tumor

Drug: DB-1303/BNT323

35 locations incl. Cerritos

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05150691·Phase 1, Phase 2·Recruiting

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

20 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting

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Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

for Adenoid Cystic Carcinoma

5 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04883671·Recruiting

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The COCOA-PAD II Trial

for Peripheral Artery Disease

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT04794530·Phase 3·Recruiting

Apply to this trial

American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

37 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting

Apply to this trial

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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STRIVE Post-Market Registry Study

for Emphysema

14 locations incl. Phoenix

Sponsor: Olympus Corporation of the Americas

Sex: All·Age: 18+

Code: NCT04302272·Recruiting

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A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

10 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting

Apply to this trial

Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

10 locations incl. Aurora

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting

Apply to this trial

IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

for Endometrial Cancer

24 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05051722·Recruiting

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Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

for Breast Cancer

7 locations incl. Washington D.C.

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04841148·Phase 2·Recruiting

Apply to this trial